Zobrazeno 1 - 10 of 15 pro vyhledávání: '"Evert Van Dijk"'
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Akademický článek
PK1 from Drosophila obscurin is an inactive pseudokinase with scaffolding properties
Autor: Thomas Zacharchenko, Till Dorendorf, Nicolas Locker, Evert Van Dijk, Anja Katzemich, Kay Diederichs, Belinda Bullard, Olga Mayans
Publikováno v: Open Biology, Vol 13, Iss 4 (2023)
Obscurins are large filamentous proteins with crucial roles in the assembly, stability and regulation of muscle. Characteristic of these proteins is a tandem of two C-terminal kinase domains, PK1 and PK2, that are separated by a long intrinsically di
Externí odkaz: https://doaj.org/article/7c1bd945c36547c1af49473a13231fe1
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3
Pre-screening of crude peptides in a serological bead-based suspension array
Autor: Nicolas Dailly, H.P.D. Fijten, Willie Loeffen, Tinka Jelsma, Fimme J. van der Wal, Evert van Dijk
Publikováno v: Journal of Virological Methods, 247, 114-118
Journal of Virological Methods 247 (2017)
Most serological assays detect antibody responses in biological samples through affinity of serum antibodies for antigens provided in the assay. Certain antigens, however, may be difficult to produce and/or may contain unwanted epitopes. In these cas
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e8401e1bcf108157581d34043d23367
https://doi.org/10.1016/j.jviromet.2017.05.008
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4
A new quantification method for assessing plasma concentrations of pemetrexed and its polyglutamate metabolites
Autor: Theo M. Luider, Sabine Visser, Marcel P. Stoop, Bruno H. Stricker, Evert van Dijk, Joachim G.J.V. Aerts
Publikováno v: Journal of Pharmaceutical and Biomedical Analysis, 128, 1-8. Elsevier
Currently no quantification method exists for potentially therapeutically relevant polyglutamate metabolites of the drug pemetrexed which is used for the treatment of lung carcinoma patients. We developed and tested an LC-MS/MS-based analytical assay
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::266d603c0ea53f4e284aa2fff04aa1de
https://doi.org/10.1016/j.jpba.2016.04.036
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5
High and individually variable enzymatic activity precludes accurate determination of pemetrexed, methotrexate and their polyglutamate metabolite concentrations in plasma
Autor: Joachim G.J.V. Aerts, Sabine Visser, Marcel P. Stoop, Theo M. Luider, Evert van Dijk, Bruno H. Stricker
Publikováno v: Journal of pharmaceutical and biomedical analysis. 148
Most drugs are metabolized in the human body. Therefore, it is essential for therapeutic drug monitoring studies to also take into account the concentrations of drug metabolites. One of the possible metabolic activities on drugs such as pemetrexed or
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a0b5adec5854813fbba0fcab6ce18d7
https://pubmed.ncbi.nlm.nih.gov/28965049
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6
Peptide library-based evaluation of T-cell receptor breadth detects defects in global and regulatory activation in human immunologic diseases
Autor: Nan-ping Weng, Elizabeth Garabedian, Irini Sereti, Evert van Dijk, Lauren K. Yokomizo, Fabio Candotti, Virginia Sheikh, John S. Barber, Robert A. Sokolic, Joshua D. Milner, Alexandra F. Freeman
Publikováno v: Proceedings of the National Academy of Sciences. 110:8164-8169
The ability of T-cells to respond to foreign antigens and to appropriately regulate this response is crucial for maintaining immune homeostasis. Using combinatorial peptide libraries, we functionally measured broad T-cell reactivity and observed impa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a3579d41478a8de3be6c6bc59343940
https://doi.org/10.1073/pnas.1302103110
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7
A viral kinase mimics S6 kinase to enhance cell proliferation
Autor: Kurtis M. Host, Brenda Temple, Joshua Buijnink, Hsing Jien Kung, Blossom Damania, Marc S. Weinberg, Jason P. Wong, Louise Giffin, Yoshihiro Izumiya, Evert van Dijk, Aadra P. Bhatt
Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, vol 113, iss 28
Significance Viruses usurp the host cell machinery to replicate, disseminate, and propagate themselves. Kaposi’s sarcoma-associated herpesvirus (KSHV) encodes a viral protein kinase (vPK) also known as ORF36. Using in silico modeling and biochemist
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a0519178d04151afc0bd15366092699
https://pubmed.ncbi.nlm.nih.gov/27342859
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8
Kinome profiling of non-canonical TRAIL signaling reveals RIP1-Src-STAT3-dependent invasion in resistant non-small cell lung cancer cells
Autor: Frank A.E. Kruyt, Maikel P. Peppelenbosch, Evert van Dijk, Godefridus J. Peters, Saravanan Yuvaraj, Steven de Jong, Thomas Wurdinger, Henk L. Dekker, Jos Joore, Wim J. Quax, Kaamar Azijli
Publikováno v: Journal of Cell Science, 125(19), 4651-4661. Company of Biologists Ltd
Journal of Cell Science, 125(19), 4651-4661. COMPANY OF BIOLOGISTS LTD
Azijli, K, Yuvaraj, S, Peppelenbosch, M P, Würdinger, T, Dekker, H, Joore, J, van Dijk, E, Quax, W J, Peters, G J, de Jong, S & Kruyt, F A 2012, ' Kinome profiling of non-canonical TRAIL signaling reveals RIP1-Src-STAT3-dependent invasion in resistant non-small cell lung cancer cells ', Journal of Cell Science, vol. 125, no. 19, pp. 4651-4661 . https://doi.org/10.1242/jcs.109587
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) triggers apoptosis selectively in tumor cells through interaction with TRAIL-R1/DR4 or TRAIL-R2/DR5 and is considered a promising avenue in cancer treatment. TRAIL resistance, howe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::357784607db910fdc772a7df93ae73c1
https://research.rug.nl/en/publications/2bc4c73e-0b9b-4cb6-9444-de0c63b8147d
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9
SUMO Assay with Peptide Arrays on Solid Support: Insights into SUMO Target Sites
Autor: Titia K. Sixma, Johannes P. M. Langedijk, Evert Van Dijk, Puck Knipscheer, Willem J. van Dijk, Rob H. Meloen, Klaus Schwamborn
Publikováno v: The Journal of Biochemistry. 144:39-49
The modification of proteins by SUMO (small ubiquitin-like modifier) regulates various cellular processes. Sumoylation often occurs on a specific lysine residue within the consensus motif psiKxE/D. However, little is known about the specificity and s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c700ca75fcbc9677a396e55479a470a2
https://doi.org/10.1093/jb/mvn039
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10
Plasma hemopexin as a potential regulator of vascular responsiveness to angiotensin II
Autor: Winston W. Bakker, Floor Spaans, Theo Borghuis, Harry van Goor, Marijke M. Faas, Evert van Dijk, Joshua Buijnink, Loubna el Bakkali
Publikováno v: Bakker, W W, Spaans, F, el Bakkali, L, Borghuis, T, van Goor, H, van Dijk, E, Buijnink, J & Faas, M M 2013, ' Plasma Hemopexin as a Potential Regulator of Vascular Responsiveness to Angiotensin II ', Reproductive Sciences, vol. 20, no. 3, pp. 234-237 . https://doi.org/10.1177/1933719112446081
Reproductive Sciences, 20(3), 234-237. SAGE Publications Inc.
This brief review focuses on the functional activities of plasma hemopexin recently recognized by several authors. In particular, the protease-like activity of hemopexin in vitro is linked with downregulation of the vascular angiotensin II receptor i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3dd1e97cd5d698beca2ff494847384c
https://pubmed.ncbi.nlm.nih.gov/22598486
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