Výsledky vyhledávání - "Everett M. Schultz"

2-(Aminomethyl)phenols, a new class of saluretic agents. 4. Effects of oxygen and/or nitrogen substitution

Autor: H. F. Russo, A. A. Deana, Smith Robert L, Cragoe Edward J, Gerald E. Stokker, Everett M. Schultz, L. S. Watson, S J deSolms, J. E. Baer

Publikováno v: Journal of Medicinal Chemistry. 25:735-742

A series of oxygen and/or nitrogen substituted 2-(aminomethyl)phenols was synthesized and tested orally in rats for saluretic and diuretic effects. Intravenous dog data are included as supplementary material to demonstrate diuretic responses, or lack

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::662dd11ab28bfde25e2857bd992846f0
https://doi.org/10.1021/jm00348a024

Zobrazit plný text záznamu

(Vinylaryloxy)acetic acids. A new class of diuretic agents. 3. [(2-Nitro-1-alkenyl)aryloxy]acetic acids

Autor: Strobauge Tp, Cragoe Edward J, N. P. Gould, Everett M. Schultz, L. S. Watson, John B. Bicking, A. A. Deana

Publikováno v: Journal of Medicinal Chemistry. 19:783-787

A series of [(2-nitro-1-alkenyl)aryloxy]acetic acids was synthesized and tested in dogs for saluretic and diuretic activity. A number of these compounds exhibit a high order of activity on iv or po administration; representative of these is (E)-[2,3-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edfcfd24e8a149d1806971c146e6e636
https://doi.org/10.1021/jm00228a009

Zobrazit plný text záznamu

2-(Aminomethyl)phenols, a new class of saluretic agents. 6. Effects of N,O-spiroannulation and subsequent quarternization

Autor: Cragoe Edward J, Gerald E. Stokker, Charles S. Sweet, H. F. Russo, L. S. Watson, Smith Robert L, Ludden Ct, Everett M. Schultz

Publikováno v: Journal of Medicinal Chemistry. 26:585-590

The synthesis of a number of 3,4-dihydrospiro-2H-1,3-benzoxazines and their corresponding benzoxazinium salts are reported. The saluretic effects displayed by these N,O-spiroannulated 2-(aminomethyl)phenols appear to be, in part, inversely related to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::135f17320f0e2a9b2c35b2e69b19b9bb
https://doi.org/10.1021/jm00358a024

Zobrazit plný text záznamu

2-(Aminomethyl)phenols, a new class of saluretic agents. 5. Fused-ring analogs

Autor: L. S. Watson, A. A. Deana, H. F. Russo, Smith Robert L, Gerald E. Stokker, Cragoe Edward J, Everett M. Schultz

Publikováno v: Journal of Medicinal Chemistry. 26:580-585

A number of bicyclic ring-fused analogues of 2-(aminomethyl)phenol were synthesized and tested orally in rats and intravenously in dogs for saluretic and diuretic effects. Of the 15 alicylic, aromatic, and heterocyclic ring-fused compounds tested, on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce3c440c9041751946d4642c7c09a0e6
https://doi.org/10.1021/jm00358a023

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání