Zobrazeno 1 - 10
of 4 297
pro vyhledávání: '"Everett E"'
Publikováno v:
Journal of International Economics and Management, Vol 22, Iss 3, Pp 46-61 (2022)
The effects of climate change are being recognized in all regions of the world and they are predicted to increase in the coming decades. This paper aims to study the impacts of economic growth, energy use, and trade liberalization on CO2 emissions in
Externí odkaz:
https://doaj.org/article/4ad9d0eaec2944dcbf2593d0c0dda3bc
Autor:
James M. Dolezal, Andrew Srisuwananukorn, Dmitry Karpeyev, Siddhi Ramesh, Sara Kochanny, Brittany Cody, Aaron S. Mansfield, Sagar Rakshit, Radhika Bansal, Melanie C. Bois, Aaron O. Bungum, Jefree J. Schulte, Everett E. Vokes, Marina Chiara Garassino, Aliya N. Husain, Alexander T. Pearson
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Safe clinical deployment of deep learning models for digital pathology requires reliable estimates of predictive uncertainty. Here the authors describe an algorithm for quantifying whole-slide image uncertainty, demonstrating their approach with mode
Externí odkaz:
https://doaj.org/article/3782f0100a0e42dd916744ca0dcd64bc
Autor:
Ari J. Rosenberg, Evgeny Izumchenko, Alexander Pearson, Zhen Gooi, Elizabeth Blair, Theodore Karrison, Aditya Juloori, Daniel Ginat, Nicole Cipriani, Mark Lingen, Hillary Sloane, Daniel L. Edelstein, Kirsten Keyser, Johannes Fredebohm, Frank Holtrup, Frederick S. Jones, Daniel Haraf, Nishant Agrawal, Everett E. Vokes
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-8 (2022)
Abstract Background Human papillomavirus (HPV)-associated oropharyngeal cancer (OPC) has a favorable prognosis which has led to efforts to de-intensify treatment. Response-adaptive de-escalated treatment is promising, however improved biomarkers are
Externí odkaz:
https://doaj.org/article/9a900a0e9acd46aa9f1e55c493688248
Autor:
Stanley I. Gutiontov, William Tyler Turchan, Liam F. Spurr, Sherin J. Rouhani, Carolina Soto Chervin, George Steinhardt, Angela M. Lager, Pankhuri Wanjari, Renuka Malik, Philip P. Connell, Steven J. Chmura, Aditya Juloori, Philip C. Hoffman, Mark K. Ferguson, Jessica S. Donington, Jyoti D. Patel, Everett E. Vokes, Ralph R. Weichselbaum, Christine M. Bestvina, Jeremy P. Segal, Sean P. Pitroda
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Immune checkpoint blockade (ICB) improves outcomes in non-small cell lung cancer (NSCLC) though most patients progress. There are limited data regarding molecular predictors of progression. In particular, there is controversy regarding the r
Externí odkaz:
https://doaj.org/article/82195ffa5c7b45b097938796d4698839
Autor:
Thomas A. Hensing, MD, MS, Xiaofei Wang, PhD, Thomas E. Stinchcombe, MD, Junheng Gao, MS, Michael V. Knopp, MD, PhD, Mark Watson, MD, PhD, Arkadiusz Z. Dudek, MD, PhD, Stephen L. Graziano, MD, Jyoti D. Patel, MD, Bryan A. Faller, MD, Konstantin H. Dragnev, MD, David Kozono, MD, PhD, Everett E. Vokes, MD
Publikováno v:
JTO Clinical and Research Reports, Vol 2, Iss 8, Pp 100208- (2021)
Introduction: The sequence of chemotherapy and pembrolizumab may affect antitumor immune response and efficacy of immunotherapy. Methods: This multicenter, randomized, phase 2 trial was designed to evaluate the efficacy of two sequences of chemothera
Externí odkaz:
https://doaj.org/article/df3a2223967b484e8c1430c2888b54cb
Autor:
Natalie Reizine, Everett E. Vokes, Ping Liu, Tien M. Truong, Rita Nanda, Gini F. Fleming, Daniel V.T. Catenacci, Alexander T. Pearson, Sandeep Parsad, Keith Danahey, Xander M. R. van Wijk, Kiang-Teck J. Yeo, Mark J. Ratain, Peter H. O’Donnell
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 12 (2020)
Background: Many cancer patients who receive chemotherapy experience adverse drug effects. Pharmacogenomics (PGx) has promise to personalize chemotherapy drug dosing to maximize efficacy and safety. Fluoropyrimidines and irinotecan have well-known ge
Externí odkaz:
https://doaj.org/article/a4fbb785a980432cbc1cd3da35a7b36b
Autor:
Yi-Hung Carol Tan, Tamara Mirzapoiazova, Brian M. Won, Li Zhu, Minu K. Srivastava, Everett E. Vokes, Aliya N. Husain, Surinder K. Batra, Sherven Sharma, Ravi Salgia
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Casitas B-lineage lymphoma (CBL) is an E3 ubiquitin ligase and a molecule of adaptor that we have shown is important for non-small-cell lung cancer (NSCLC). We investigated if MET is a target of CBL and if enhanced in CBL-altered NSCLC. We s
Externí odkaz:
https://doaj.org/article/16f501031f654eb7b913e9777d40b719
Autor:
Tanguy Y Seiwert, XiaoZhe Wang, Jana Heitmann, Vivian Villegas-Bergazzi, Kam Sprott, Stephen Finn, Esther O'Regan, Allan D Farrow, Ralph R Weichselbaum, Mark W Lingen, Ezra E W Cohen, Kerstin Stenson, David T Weaver, Everett E Vokes
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e102112 (2014)
BackgroundInduction chemotherapy is a common therapeutic option for patients with locoregionally-advanced head and neck cancer (HNC), but it remains unclear which patients will benefit. In this study, we searched for biomarkers predicting the respons
Externí odkaz:
https://doaj.org/article/8c508f0d8e494bdca4110695a9b7a55c
Autor:
Dolezal, James M, Srisuwananukorn, Andrew, Karpeyev, Dmitry, Ramesh, Siddhi, Kochanny, Sara, Cody, Brittany, Mansfield, Aaron, Rakshit, Sagar, Bansa, Radhika, Bois, Melanie, Bungum, Aaron O, Schulte, Jefree J, Vokes, Everett E, Garassino, Marina Chiara, Husain, Aliya N, Pearson, Alexander T
A model's ability to express its own predictive uncertainty is an essential attribute for maintaining clinical user confidence as computational biomarkers are deployed into real-world medical settings. In the domain of cancer digital histopathology,
Externí odkaz:
http://arxiv.org/abs/2204.04516
Autor:
Benjamin D Ferguson, Ren Liu, Cleo E Rolle, Yi-Hung Carol Tan, Valery Krasnoperov, Rajani Kanteti, Maria S Tretiakova, Gustavo M Cervantes, Rifat Hasina, Robyn D Hseu, A John Iafrate, Theodore Karrison, Mark K Ferguson, Aliya N Husain, Leonardo Faoro, Everett E Vokes, Parkash S Gill, Ravi Salgia
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e67668 (2013)
Despite progress in locoregional and systemic therapies, patient survival from lung cancer remains a challenge. Receptor tyrosine kinases are frequently implicated in lung cancer pathogenesis, and some tyrosine kinase inhibition strategies have been
Externí odkaz:
https://doaj.org/article/49dc221d374e40ea970d698d828f4a91