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pro vyhledávání: '"Evelyne Tack"'
Autor:
Jan D'hooge, Peter Carmeliet, Myriam Baes, Andrey Anisimov, Massimiliano Mazzone, Carmen Roncal, Lorenzo Veschini, Yannick Jönsson, Daniela Dettori, Veronica Finisguerra, Rodrigo Leite de Oliveira, Evelyne Tack, Sofie Deschoemaeker, Matthias Hofmann, Annelies Peeters, Yukiji Takeda, Koen Debackere, Anne-Theres Henze, Kari Alitalo
Publikováno v:
Cancer Cell
SummaryThe success of chemotherapy in cancer treatment is limited by scarce drug delivery to the tumor and severe side-toxicity. Prolyl hydroxylase domain protein 2 (PHD2) is an oxygen/redox-sensitive enzyme that induces cellular adaptations to stres