Výsledky vyhledávání - "Evelyne Silva Brum"

Akademický článek

Kinin B2 Receptor Mediates Cisplatin-Induced Painful Peripheral Neuropathy by Intracellular Kinase Pathways and TRPA1 Channel Sensitisation

Autor: Gabriela Becker, Maria Fernanda Pessano Fialho, Evelyne Silva Brum, Sara Marchesan Oliveira

Publikováno v: Pharmaceuticals, Vol 16, Iss 7, p 959 (2023)

Chemotherapy-induced peripheral neuropathy is a severe clinical problem frequently associated with cisplatin use. Although its pathophysiology is poorly understood, it is known that kinin receptors and the transient receptor potential ankyrin 1 (TRPA

Externí odkaz: https://doaj.org/article/82117848fa6e4c6b89af85b9a5df23cd

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Akademický článek

Kinin B2 and B1 Receptors Activation Sensitize the TRPA1 Channel Contributing to Anastrozole-Induced Pain Symptoms

Autor: Maria Fernanda Pessano Fialho, Evelyne Silva Brum, Gabriela Becker, Indiara Brusco, Sara Marchesan Oliveira

Publikováno v: Pharmaceutics, Vol 15, Iss 4, p 1136 (2023)

Aromatase inhibitors (AIs) cause symptoms of musculoskeletal pain, and some mechanisms have been proposed to explain them. However, signaling pathways downstream from kinin B2 (B2R) and B1 (B1R) receptor activation and their possible sensitizing of t

Externí odkaz: https://doaj.org/article/c38cd412f8b14276980af566e7295591

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