Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Evelyne Ségal‐Bendirdjian"'
Autor:
Delphine Garsuault, Claire Bouyer, Eric Nguyen, Rohan Kandhari, Martina Prochazkova‐Carlotti, Edith Chevret, Patricia Forgez, Evelyne Ségal‐Bendirdjian
Publikováno v:
Molecular Oncology, Vol 14, Iss 6, Pp 1310-1326 (2020)
Telomerase (hTERT) reactivation and sustained expression is a key event in the process of cellular transformation. Therefore, the identification of the mechanisms regulating hTERT expression is of great interest for the development of new anticancer
Externí odkaz:
https://doaj.org/article/34bfe5361471494785eee5ce43e43e06
Autor:
Alain Chebly, Jean-Marie Peloponese, Evelyne Ségal-Bendirdjian, Jean-Philippe Merlio, Roland Tomb, Edith Chevret
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/11f49aa4fcfa404cadd0a4d36d9c1c77
Autor:
Audrey Astori, Gabriel Matherat, Isabelle Munoz, Emilie-Fleur Gautier, Didier Surdez, Yaël Zermati, Frédérique Verdier, Sakina Zaidi, Vincent Feuillet, Amir Kadi, Evelyne Lauret, Olivier Delattre, Carine Lefèvre, Michaela Fontenay, Evelyne Ségal-Bendirdjian, Isabelle Dusanter-Fourt, Didier Bouscary, Olivier Hermine, Patrick Mayeux, Frédéric Pendino
Publikováno v:
Haematologica, Vol 107, Iss 1 (2020)
The gene CXXC5, encoding a retinoid-inducible nuclear factor (RINF), is located within a region at 5q31.2 commonly deleted in myelodysplastic syndrome and adult acute myeloid leukemia. RINF may act as an epigenetic regulator and has been proposed as
Externí odkaz:
https://doaj.org/article/2dd159ffad414e7599e33471931871d4
Autor:
Eric Nguyen, Andréa Richerolle, Júlia Sánchez-Bellver, Jacqueline Varennes, Evelyne Ségal-Bendirdjian
Publikováno v:
Biomedicines, Vol 10, Iss 3, p 695 (2022)
Telomerase reactivation is responsible for telomere preservation in about 90% of cancers, providing cancer cells an indefinite proliferating potential. Telomerase consists of at least two main subunits: a catalytic reverse transcriptase protein (hTER
Externí odkaz:
https://doaj.org/article/4487681233fb4afaaccb1dd2013b1f72
Autor:
Joëlle El Hajj, Eric Nguyen, Qingyuan Liu, Claire Bouyer, Eric Adriaenssens, George Hilal, Evelyne Ségal-Bendirdjian
Publikováno v:
Molecular Cancer, Vol 17, Iss 1, Pp 1-13 (2018)
Abstract Background Since tumor growth requires reactivation of telomerase (hTERT), this enzyme is a challenging target for drug development. Therefore, it is of great interest to identify telomerase expression and activity regulators. Retinoids are
Externí odkaz:
https://doaj.org/article/99fec643e2634a0596c2097bc839caa0
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
Telomerase plays a critical role in stem cell function and tissue regeneration that depends on its ability to elongate telomeres. For nearly two decades, it turned out that TERT regulates a broad spectrum of functions including signal transduction, g
Externí odkaz:
https://doaj.org/article/e4cee2c7024c431ba39162868fd15d08
Autor:
Jean-Luc Carrier, Pasha Javadi, Emilie Bourrier, Céline Camus, Evelyne Ségal-Bendirdjian, Aïda Karniguian
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50408 (2012)
A determining role has been assigned to cAMP in the signaling pathways that relieve resistance to anti-leukemia differentiation therapy. However, the underlying mechanisms have not been elucidated yet. Here, we identify cFos as a critical cAMP effect
Externí odkaz:
https://doaj.org/article/8e6924c477d44a5caee9134a8aa122fc
Autor:
Evelyne Ségal-Bendirdjian, Eric Nguyen, Mona Samy, Frédéric Pendino, Josette Hillion, Laure Deville
Imatinib mesylate has shown remarkable efficacy in the treatment of patients in the chronic phase of chronic myeloid leukemia. However, despite an overall significant hematological and cytogenetic response, imatinib therapy may favor the emergence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a90fc164c89b12fb8070f3bf3b73dd12
https://doi.org/10.1158/1535-7163.c.6535344
https://doi.org/10.1158/1535-7163.c.6535344
Autor:
Evelyne Ségal-Bendirdjian, Jean Bénard, Sétha Douc-Rasy, Sophie Bombard, Eric Nguyen, Josette Hillion, Frédéric Pendino, Charles-Henry Gattolliat, Mona Samy
PDF file, 84K, Loss of the mutant P53 alleles during the culture expansion of the DN-hTERT transduced IGR-N-91 cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03b92ef3498cb10691b3b6d8e27e0cbd
https://doi.org/10.1158/1535-7163.22496220
https://doi.org/10.1158/1535-7163.22496220
Autor:
Evelyne Ségal-Bendirdjian, Jean Bénard, Sétha Douc-Rasy, Sophie Bombard, Eric Nguyen, Josette Hillion, Frédéric Pendino, Charles-Henry Gattolliat, Mona Samy
PDF file, 81K.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83aeff53257f4fb944298ca1a298d8f4
https://doi.org/10.1158/1535-7163.22496214
https://doi.org/10.1158/1535-7163.22496214