Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Evelyne Marion"'
Autor:
André Bodson, Jens Behrends, G. Servais, Dominique Gauguier, Evelyne Marion, Pamela J. Kaisaki, Daubresse Jc, Claude Szpirer, J. Mockel, Cyril Gueydan, Jonathan C. Levy, Georges Krzentowski, Valérie Pouillon, Stéphane Schurmans, Véronique Kruys
Publikováno v:
Scopus-Elsevier
Diabetes, 51
Diabetes, 51
Genetic susceptibility to type 2 diabetes involves many genes, most of which are still unknown. The lipid phosphatase SHIP2 is a potent negative regulator of insulin signaling and sensitivity in vivo and is thus a good candidate gene. Here we report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3155af37c1761a84281f3d6f79ec25e8
https://ora.ox.ac.uk/objects/uuid:92c3a867-8afa-473e-9daf-ff356eff3896
https://ora.ox.ac.uk/objects/uuid:92c3a867-8afa-473e-9daf-ff356eff3896
Autor:
Jean-Pierre Riveline, Peng Y. Woon, Pamela J. Kaisaki, Dominique Gauguier, Martin Farrall, Marc Delepine, Mark Lathrop, Jonathan C. Levy, Liam Sebag-Montefiore, Guillaume Charpentier, Nathalie Vionnet, Stephan Menzel, Stéphane Schurmans, Evelyne Marion, Steven P. Wilder
Publikováno v:
Diabetes (New York, N.Y.), 53 (7
Europe PubMed Central
Europe PubMed Central
Type II SH2 domain-containing inositol 5-phosphatase (INPPL1, or SHIP2) plays an important role in the control of insulin sensitivity. INPPL1 mutations affecting gene function have been found in rat models of type 2 diabetes and hypertension and in t
Autor:
Christophe Erneux, Sylvie Giuriato, Xavier Pesesse, Evelyne Marion, Cécile Viala, Bernard Payrastre, Stéphane Bodin, Stéphane Schurmans, Takehiko Sasaki, Joseph M. Penninger
Publikováno v:
The Biochemical journal. 376(Pt 1)
Src homology domain 2-containing inositol 5-phosphatases 1 and 2 (SHIP1 and SHIP2) are capable of dephosphorylating the second messenger PtdIns(3,4,5)P3 (phosphatidylinositol 3,4,5-trisphosphate) and interacting with several signalling proteins. SHIP