Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Evelyne M. Quinton"'
Autor:
Sebastien Dropsit, Pieter F. W. Stouten, Linda Tomaskovic, Thierry Christophe, Ellen van der Aar, Maarten Gees, Luc Nelles, Mia Jans, Monica Borgonovi, Evelyne M. Quinton, Katja Conrath, Jan Van Der Schueren, Caroline Joannesse, Hans Kelgtermans, Martin James Inglis Andrews, Sebastien Laurent Xavier Martina, Oscar Mammoliti, Ann De Blieck, Steven Emiel Van Der Plas, Tom De Munck
Publikováno v:
Journal of Medicinal Chemistry. 61:1425-1435
Cystic fibrosis (CF) is caused by mutations in the gene for the cystic fibrosis transmembrane conductance regulator (CFTR). With the discovery of Ivacaftor and Orkambi, it has been shown that CFTR function can be partially restored by administering o
Autor:
Kristof T. J. Loones, Anh Tho Nguyen, Johan Wouters, Evelyne M. Quinton, Oscar Mammoliti, Guy Van Lommen
Publikováno v:
Tetrahedron. 69(5):1669-1680
Two new single-step reactions allowing the construction of two heterocyclic motifs are reported. Both processes involve 5-substituted 1,3,4-thiadiazol-2- amines as starting materials. Reaction with 1-fluoro-2-nitrobenzenes in presence of Hünig's bas
Autor:
Oscar Mammoliti, Johan Wouters, Kristof T. J. Loones, Guy Van Lommen, Anh Tho Nguyen, Evelyne M. Quinton
Publikováno v:
ChemInform. 44
Two new single-step reactions allowing the construction of two heterocyclic motifs are reported. Both processes involve 5-substituted 1,3,4-thiadiazol-2-amines as starting materials. Reaction with 1-fluoro-2-nitrobenzenes in presence of Hunig's base