Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Evelyne Joseph"'
Publikováno v:
Journal of Biological Chemistry. 272:28102-28106
The peripheral type benzodiazepine receptor (PBR) binds benzodiazepines such as RO5-4864 and isoquinoline carboxamide derivatives such as PK11195. This receptor includes an Mr 18,000 isoquinoline-binding subunit predominantly located in mitochondrial
Publikováno v:
Gene. 155:195-199
The human peripheral-type benzodiazepine receptor (PBR) has been produced in Saccharomyces cerevisiae where it retains its pharmacological properties [Riond et al., Eur. J. Pharmacol. 208 (1991) 307–312]. As the rate of production was low, we analy
Autor:
Roseli C. Farges, Pascual Ferrara, Gérard Le Fur, Evelyne Joseph-Liauzun, David Shire, Daniel Caput, Gérard Loison
Publikováno v:
FEBS Letters. 335:305-308
The 18 kDa peripheral benzodiazepine receptor (PBR) can be labelled by benzodiazepines, such as Ro5-4864, and isoquinoline carboxamides such as PK11195. These two compounds are reversible competitive inhibitors of each other. However, while the bindi
Autor:
R. Legoux, E. Marchese, Evelyne Joseph-Liauzun, Pascal Leplatois, Pascual Ferrara, V. Guerveno
Publikováno v:
Gene. 86:291-295
A synthetic gene coding for the C-terminal 153 amino acids of the human interleukin-1 beta (IL-1 beta) was used to produce large quantities of recombinant IL-1 beta in Escherichia coli. The expression of the synthetic gene was under the control of an
Publikováno v:
The Journal of biological chemistry. 273(4)
The peripheral benzodiazepine receptor, implicated in the transport of cholesterol from the outer to the inner mitochondrial membrane, is predicted by hydropathy analysis to feature five membrane-spanning domains, with the amino terminus within the m
Autor:
Willem Roskam, Claude Lazdunski, Roland Lloubès, Jamila Anba, Jean-Marie Pagès, Evelyne Joseph-Liauzun, Daniel Baty, David Shire
Publikováno v:
Gene. 53:219-226
We have studied the synthesis, processing and export of human growth-hormone-releasing factor (hGRF) in Escherichia coli transformed with a plasmid constructed for the expression of hGRF as a hybrid protein. A DNA fragment containing the entire seque
Publikováno v:
Biochimie. 63:419-424
Resume Deux mutants particuliers ayant un taux de synthese des proteines altere nous ont servi a mettre en evidence un defaut d'expression des genes promoteur-distaux par rapport aux genes promoteurproximaux dans les operons lactose et galactose. Cet
Publikováno v:
FEMS Microbiology Letters. 10:389-393
Publikováno v:
Molecular and General Genetics MGG. 187:291-296
We attempted to correlate structural modifications of the adenosine 3',5' cyclic monophosphate (cAMP) receptor protein (CAP), to changes in some of its in vivo regulatory functions such as (i) stimulation of the lactose operon expression and (ii) con
Autor:
Evelyne Joseph, Jean-Luc Guesdon
Publikováno v:
Analytical Biochemistry. 119:335-340
A specific and sensitive β-galactosidase immunoassay is described. A cyclic AMP-β-galactosidase conjugate is used as the labeled cyclic AMP derivative in a competitive binding assay. By determining the β-galactosidase activity, the concentration o