Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Evelyne Fontaine"'
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Despite reinvigorated efforts in Tuberculosis (TB) drug discovery over the past 20 years, relatively few new drugs and candidates have emerged with clear utility against drug resistant TB. Over the same period, significant technological advances and
Externí odkaz:
https://doaj.org/article/114794c09691476e8321f3938850da66
Autor:
Martin Gengenbacher, Matthew D. Zimmerman, Christine Roubert, Véronique Dartois, Wassihun Wedajo Aragaw, Thomas Dick, Sophie Lagrange, Evelyne Fontaine
Publikováno v:
Antimicrobial Agents and Chemotherapy
Cyclohexyl-griselimycin is a preclinical candidate for use against tuberculosis (TB). Here, we show that this oral cyclodepsipeptide is also active against the intrinsically drug-resistant nontuberculous mycobacterium Mycobacterium abscessus in vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::385e951f959363242e3d43c927e3c651
https://doi.org/10.1128/aac.01400-21
https://doi.org/10.1128/aac.01400-21
Autor:
Eric L. Nuermberger, Michel Geslin, Nicole C. Ammerman, Evelyne Fontaine, Florence Bordon-Pallier, Holger Hoffmann, Peer Lukat, Nestor Zaburannyi, Mark Brönstrup, Rolf Müller, Hans Matter, Dirk W. Heinz, Sandeep Tyagi, Sylvie Sordello, Armin Bauer, Michael Kurz, Kai Borchers, Sylvie Klieber, Courtemanche Gilles, Jacques H. Grosset, Silke C. Wenzel, Markus Kohlmann, Angela Kling, Christine Lair, María Belén Barrio, Jennifer Herrmann, Sophie Lagrange, Deepak V. Almeida, Laurent Fraisse, Claudia König, Martin Gerlitz, Peter Hammann
Publikováno v:
Science. 348:1106-1112
New for old—TB drug development Tuberculosis (TB) is a global health threat for which there is only lengthy drug treatment. Patients need to consume multiple tablets over several months and frequently fail to complete their treatment. Consequently,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9258e74de54eb4c0ff301e18e90e713
https://doi.org/10.1126/science.aaa4690
https://doi.org/10.1126/science.aaa4690
Autor:
Angela, Kling, Peer, Lukat, Deepak V, Almeida, Armin, Bauer, Evelyne, Fontaine, Sylvie, Sordello, Nestor, Zaburannyi, Jennifer, Herrmann, Silke C, Wenzel, Claudia, König, Nicole C, Ammerman, María Belén, Barrio, Kai, Borchers, Florence, Bordon-Pallier, Mark, Brönstrup, Gilles, Courtemanche, Martin, Gerlitz, Michel, Geslin, Peter, Hammann, Dirk W, Heinz, Holger, Hoffmann, Sylvie, Klieber, Markus, Kohlmann, Michael, Kurz, Christine, Lair, Hans, Matter, Eric, Nuermberger, Sandeep, Tyagi, Laurent, Fraisse, Jacques H, Grosset, Sophie, Lagrange, Rolf, Müller
Publikováno v:
Science (New York, N.Y.). 348(6239)
The discovery of Streptomyces-produced streptomycin founded the age of tuberculosis therapy. Despite the subsequent development of a curative regimen for this disease, tuberculosis remains a worldwide problem, and the emergence of multidrug-resistant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::353ea30df51bdd49e271b0d93e8fabac
https://pubmed.ncbi.nlm.nih.gov/26295835
https://pubmed.ncbi.nlm.nih.gov/26295835
Autor:
Régis Steinberg, Jean-Pierre Maffrand, Pierre Roger, Georgette Gout, Philippe Soubrie, Evelyne Fontaine, Christine Lair, Danielle Gully, Marc Pascal, Valerie Darre, Michel Geslin, Jacques Simiand, Gérard Le Fur, Rebecca M. Pruss, Pierre-Eric Rouby, Bernard Scatton, Laurence Serva, Josette Guitard, Claudine Marcy, D. Rodier, Guy Griebel
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 301:322-332
4-(2-Chloro-4-methoxy-5-methylphenyl)- N -[(1 S )-2-cyclopropyl-1- (3-fluoro-4-methylphenyl)ethyl]5-methyl- N -(2-propynyl)-1,3-thiazol-2-amine hydrochloride (SSR125543A), a new 2-aminothiazole derivative, shows nanomolar affinity for human cloned or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::118abb2bf823c936be899607cd7ac2de
https://doi.org/10.1124/jpet.301.1.322
https://doi.org/10.1124/jpet.301.1.322
Autor:
Mohamed Maftouh, Stéphanie Tissandié, Evelyne Fontaine, Michel Geslin, Laurence Serva, Pierre Roger, Eliane Roussey, Claudie Namane, Jerome Meneyrol
Publikováno v:
ChemInform. 33
The preparation of novel optically active benzylic amines by the enantioselective reduction of phenone oximes using chiral oxazaborolidine is described. The choice of the chiral 1,2-amino alcohol (S)-diphenylvalinol as chiral inducer and that of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cab9b79650a4dd1003c038297412560
https://doi.org/10.1002/chin.200207078
https://doi.org/10.1002/chin.200207078
Autor:
Danielle, Gully, Michel, Geslin, Laurence, Serva, Evelyne, Fontaine, Pierre, Roger, Christine, Lair, Valerie, Darre, Claudine, Marcy, Pierre-Eric, Rouby, Jacques, Simiand, Josette, Guitard, Georgette, Gout, Regis, Steinberg, Daniel, Rodier, Guy, Griebel, Philippe, Soubrie, Marc, Pascal, Rebecca, Pruss, Bernard, Scatton, Jean-Pierre, Maffrand, Gerard, Le Fur
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 301(1)
4-(2-Chloro-4-methoxy-5-methylphenyl)-N-[(1S)-2-cyclopropyl-1- (3-fluoro-4-methylphenyl)ethyl]5-methyl-N-(2-propynyl)-1,3-thiazol-2-amine hydrochloride (SSR125543A), a new 2-aminothiazole derivative, shows nanomolar affinity for human cloned or nativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::44a7f2de82503cc7b8cae6658b43c235
https://pubmed.ncbi.nlm.nih.gov/11907190
https://pubmed.ncbi.nlm.nih.gov/11907190
Publikováno v:
Crop Science
Crop Science, Crop Science Society of America, 1993, 33 (2), pp.267-270
Crop Science, Crop Science Society of America, 1993, 33 (2), pp.267-270
Pod number is the most explicative component of the yield variability of pea (Pisum sativum L.). To understand the processes that determine pod number, the timing of reproductive abortion, seed development, and growth were studied. Cultivar Solara wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21bc21cdab2b94c028377ffb3aa0252b
https://hal.inrae.fr/hal-02701474
https://hal.inrae.fr/hal-02701474
