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When tumorigenic cultured cell populations are inoculated into nude mice, the tumorigenic process generally requires further progression and selection in vivo. This in vivo progression should be reflected in the altered properties of the tumor cells,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c8d4526e007010a6865305dad2cca66
https://doi.org/10.1159/000413316
https://doi.org/10.1159/000413316
Autor:
Robert S. Wells, Lawrence M. Holland, Evelyn W. Campbell, Paul M. Kraemer, Douglas E. Swartzendruber
Publikováno v:
JNCI: Journal of the National Cancer Institute.
Cultured mouse cells were tested for tumorigenicity in nude mice with both a conventional assay (injection of cell suspensions) and a new test involving implantation of cells grown on gelatin sponges. Sublines of Balb/3T3 cells, obtained from differe