Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Evelyn Stinckens"'
Autor:
Ondrej Adamovsky, Ksenia J. Groh, Anna Białk-Bielińska, Beate I. Escher, R. Beaudouin, Liadys Mora Lagares, Knut Erik Tollefsen, Martina Fenske, Ewa Mulkiewicz, Nicolas Creusot, Anita Sosnowska, Susana Loureiro, Jonny Beyer, Guillermo Repetto, Alja Štern, Isabel Lopes, Marta Monteiro, Andrea Zikova-Kloas, Tina Eleršek, Marjan Vračko, Szymon Zdybel, Tomasz Puzyn, Weronika Koczur, Jane Ebsen Morthorst, Henrik Holbech, Gunnar Carlsson, Stefan Örn, Óscar Herrero, Ayesha Siddique, Matthias Liess, Georg Braun, Vanessa Srebny, Bojana Žegura, Nathalie Hinfray, François Brion, Dries Knapen, Ellen Vandeputte, Evelyn Stinckens, Lucia Vergauwen, Lars Behrendt, Maria João Silva, Ludek Blaha, Katerina Kyriakopoulou
Publikováno v:
Environment International, Vol 189, Iss , Pp 108728- (2024)
Bisphenol A alternatives are manufactured as potentially less harmful substitutes of bisphenol A (BPA) that offer similar functionality. These alternatives are already in the market, entering the environment and thus raising ecological concerns. Howe
Externí odkaz:
https://doaj.org/article/fe4cf4bb15944b03afce9b482e0df265
Autor:
Albert Braeuning, Patrick Balaguer, William Bourguet, Jordi Carreras-Puigvert, Katreece Feiertag, Jorke H. Kamstra, Dries Knapen, Dajana Lichtenstein, Philip Marx-Stoelting, Jonne Rietdijk, Kristin Schubert, Ola Spjuth, Evelyn Stinckens, Kathrin Thedieck, Rik van den Boom, Lucia Vergauwen, Martin von Bergen, Neele Wewer, Daniel Zalko
Publikováno v:
Frontiers in Toxicology, Vol 6 (2024)
Externí odkaz:
https://doaj.org/article/c83d238d04114c37b33e13818a71f8db
Autor:
Albert Braeuning, Patrick Balaguer, William Bourguet, Jordi Carreras-Puigvert, Katreece Feiertag, Jorke H. Kamstra, Dries Knapen, Dajana Lichtenstein, Philip Marx-Stoelting, Jonne Rietdijk, Kristin Schubert, Ola Spjuth, Evelyn Stinckens, Kathrin Thedieck, Rik van den Boom, Lucia Vergauwen, Martin von Bergen, Neele Wewer, Daniel Zalko
Publikováno v:
Frontiers in Toxicology, Vol 5 (2023)
In past times, the analysis of endocrine disrupting properties of chemicals has mainly been focused on (anti-)estrogenic or (anti-)androgenic properties, as well as on aspects of steroidogenesis and the modulation of thyroid signaling. More recently,
Externí odkaz:
https://doaj.org/article/7ee7a592f1ad4eba98f91899309c0cf9
Autor:
Louise Ramhøj, Marta Axelstad, Yoni Baert, Ana I. Cañas-Portilla, Frédéric Chalmel, Lars Dahmen, Antonio De La Vieja, Bertrand Evrard, Ann-Cathrin Haigis, Timo Hamers, Kim Heikamp, Henrik Holbech, Patricia Iglesias-Hernandez, Dries Knapen, Lorna Marchandise, Jane E. Morthorst, Nikolai Georgiev Nikolov, Ana C. V. E. Nissen, Michael Oelgeschlaeger, Kostja Renko, Vera Rogiers, Gerrit Schüürmann, Evelyn Stinckens, Mette H. Stub, Monica Torres-Ruiz, Majorie Van Duursen, Tamara Vanhaecke, Lucia Vergauwen, Eva Bay Wedebye, Terje Svingen
Publikováno v:
Frontiers in Toxicology, Vol 5 (2023)
Current test strategies to identify thyroid hormone (TH) system disruptors are inadequate for conducting robust chemical risk assessment required for regulation. The tests rely heavily on histopathological changes in rodent thyroid glands or measurin
Externí odkaz:
https://doaj.org/article/11318ef2537f459fb447b21949bc2674
Autor:
Anne E. Thessen, Skylar Marvel, J. C. Achenbach, Stephan Fischer, Melissa A. Haendel, Kimberly Hayward, Nils Klüver, Sarah Könemann, Jessica Legradi, Pamela Lein, Connor Leong, J. Erik Mylroie, Stephanie Padilla, Dante Perone, Antonio Planchart, Rafael Miñana Prieto, Arantza Muriana, Celia Quevedo, David Reif, Kristen Ryan, Evelyn Stinckens, Lisa Truong, Lucia Vergauwen, Colette Vom Berg, Mitch Wilbanks, Bianca Yaghoobi, Jon Hamm
Publikováno v:
Frontiers in Toxicology, Vol 4 (2022)
Toxicological evaluation of chemicals using early-life stage zebrafish (Danio rerio) involves the observation and recording of altered phenotypes. Substantial variability has been observed among researchers in phenotypes reported from similar studies
Externí odkaz:
https://doaj.org/article/aa31689544a84557af841ca42ae42ad4
Toward an AOP Network-Based Tiered Testing Strategy for the Assessment of Thyroid Hormone Disruption
Autor:
Dries Knapen, Henrik Holbech, Gerald T. Ankley, Evelyn Stinckens, Daniel L. Villeneuve, Lucia Vergauwen, Jenna E. Cavallin
Publikováno v:
Environ Sci Technol
Environmental science and technology
Environmental Science & Technology
Knapen, D, Stinckens, E, Cavallin, J E, Ankley, G T, Holbech, H, Villeneuve, D L & Vergauwen, L 2020, ' Toward an AOP network-based tiered testing strategy for the assessment of thyroid hormone disruption ', Environmental Science & Technology, vol. 54, no. 14, pp. 8491-8499 . https://doi.org/10.1021/acs.est.9b07205
Environmental science and technology
Environmental Science & Technology
Knapen, D, Stinckens, E, Cavallin, J E, Ankley, G T, Holbech, H, Villeneuve, D L & Vergauwen, L 2020, ' Toward an AOP network-based tiered testing strategy for the assessment of thyroid hormone disruption ', Environmental Science & Technology, vol. 54, no. 14, pp. 8491-8499 . https://doi.org/10.1021/acs.est.9b07205
A growing number of environmental pollutants are known to adversely affect the thyroid hormone system, and major gaps have been identified in the tools available for the identification, and the hazard and risk assessment of these thyroid hormone disr
Autor:
Daniel L. Villeneuve, Evelyn Stinckens, Brett R. Blackwell, Dries Knapen, Lucia Vergauwen, Gerald T. Ankley
Publikováno v:
Environmental Science & Technology
Environmental science and technology
Environ Sci Technol
Environmental science and technology
Environ Sci Technol
A set of adverse outcome pathways (AOPs) linking inhibition of thyroperoxidase and deiodinase to impaired swim bladder inflation in fish has recently been developed. These AOPs help to establish links between these thyroid hormone (TH) disrupting mol
Autor:
Joe Swintek, Eric C. Randolph, Evy Verbueken, Ellen D. G. Michiels, Dries Knapen, Chloé Bars, Gerald T. Ankley, Isabelle J. Gabriëls, Anthony L. Schroeder, Daniel L. Villeneuve, Lucia Vergauwen, Jenna E. Cavallin, Krysta R. Fitzpatrick, Travis W. Saari, Jelena Periz-Stanacev, Evelyn Stinckens, Serina L. Robinson, Steven Van Cruchten
Publikováno v:
General and comparative endocrinology
The hypothalamic-pituitary-thyroid (HPT) axis is known to play a crucial role in the development of teleost fish. However, knowledge of endogenous transcription profiles of thyroid-related genes in developing teleosts remains fragmented. We selected
Autor:
Lucia Vergauwen, Waleed F.A. Marei, Jonathan S. Ball, Dries Knapen, Isabelle J. Gabriëls, Ellen D. G. Michiels, Evelyn Stinckens, Chris Van Ginneken, Anna Tochwin, Evy Verbueken, Steven Van Cruchten, Chloé Bars, Jelena Periz-Stanacev
Publikováno v:
International Journal of Molecular Sciences
Volume 19
Issue 12
International Journal of Molecular Sciences, Vol 19, Iss 12, p 3976 (2018)
International journal of molecular sciences
Volume 19
Issue 12
International Journal of Molecular Sciences, Vol 19, Iss 12, p 3976 (2018)
International journal of molecular sciences
The zebrafish (Danio rerio) embryo is currently explored as an alternative for developmental toxicity testing. As maternal metabolism is lacking in this model, knowledge of the disposition of xenobiotics during zebrafish organogenesis is pivotal in o
Autor:
Adrian Covaci, Dries Knapen, Walid Maho, Lucia Vergauwen, Hilda Witters, Anthony L. Schroeder, Evelyn Stinckens, Gerald T. Ankley, Brett R. Blackwell, Ronny Blust, Daniel L. Villeneuve
Publikováno v:
Aquatic Toxicology. 173:204-217
Disruption of the thyroid hormone (TH) system, an important mode of action, can lead to ecologically relevant adverse outcomes, especially during embryonic development. The present study characterizes the effects of disruption of TH synthesis on swim