Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Evelyn N. Kouwenhoven"'
Autor:
Jieqiong Qu, Sabine E.J. Tanis, Jos P.H. Smits, Evelyn N. Kouwenhoven, Martin Oti, Ellen H. van den Bogaard, Colin Logie, Hendrik G. Stunnenberg, Hans van Bokhoven, Klaas W. Mulder, Huiqing Zhou
Publikováno v:
Cell Reports, Vol 25, Iss 12, Pp 3490-3503.e4 (2018)
Summary: Transcription factor p63 is a key regulator of epidermal keratinocyte proliferation and differentiation. Mutations in the p63 DNA-binding domain are associated with ectrodactyly, ectodermal dysplasia, and cleft lip/palate (EEC) syndrome. How
Externí odkaz:
https://doaj.org/article/6919d3e388824bdd9a978149c19f51f2
Publikováno v:
Genomics Data, Vol 5, Iss C, Pp 159-163 (2015)
The transcription factor p63 is a key regulator in epidermal keratinocyte proliferation and differentiation. However, the role of p63 in gene regulation during these processes is not well understood. To investigate this, we recently generated genome-
Externí odkaz:
https://doaj.org/article/93f46654cd4c48a193f3f3185f6c18d8
Autor:
Colin Logie, Klaas W. Mulder, Hans van Bokhoven, Evelyn N. Kouwenhoven, Jieqiong Qu, Martin Oti, Hendrik G. Stunnenberg, Sabine E.J. Tanis, Jos P.H. Smits, E. van den Bogaard, Huiqing Zhou
Publikováno v:
Cell Reports, Vol 25, Iss 12, Pp 3490-3503.e4 (2018)
Cell Reports, 25, 3490-3503.e4
Cell Reports, 25, 12, pp. 3490-3503.e4
Cell Reports, 25, 3490-3503.e4
Cell Reports, 25, 12, pp. 3490-3503.e4
Summary: Transcription factor p63 is a key regulator of epidermal keratinocyte proliferation and differentiation. Mutations in the p63 DNA-binding domain are associated with ectrodactyly, ectodermal dysplasia, and cleft lip/palate (EEC) syndrome. How
Autor:
Arjan P.M. de Brouwer, Michael Schweizer, Eziuche Amadike Ugbogu, Lilian Mary Schweizer, Sonja Ursula Wippler, Evelyn N. Kouwenhoven, Matthew Euston
Publikováno v:
FEMS Yeast Research, 13, 3, pp. 291-301
FEMS Yeast Research, 13, 291-301
FEMS Yeast Research, 13, 291-301
Item does not contain fulltext The gene products of the five-membered PRS gene family in Saccharomyces cerevisiae have been shown to exist as three minimal functional entities, Prs1/Prs3, Prs2/Prs5, and Prs4/Prs5, each capable of supporting cell viab
Autor:
Christiane Zweier, Arif B. Ekici, Hendrik G. Stunnenberg, Evelyn N. Kouwenhoven, Huiqing Zhou, Martin Oti, Susanne Kjaergaard, Georgia Vasileiou, Anne Gregor, Juliane Hoyer, André Reis, Steffen Uebe, Heinrich Sticht, Anita Rauch
Publikováno v:
American Journal of Human Genetics, 93, 124-31
American Journal of Human Genetics, 93, 1, pp. 124-31
American Journal of Human Genetics, 93, 1, pp. 124-31
Contains fulltext : 117375.pdf (Publisher’s version ) (Open Access) An increasing number of genes involved in chromatin structure and epigenetic regulation has been implicated in a variety of developmental disorders, often including intellectual di
Autor:
Marcel A.G. van der Heyden, Bart Kok, Vadim G. Fedorov, Evelyn N. Kouwenhoven, Igor R. Efimov, Øivind Tøien, Brian M. Barnes, Tobias Opthof
Publikováno v:
DNA Sequence. 18:380-384
Conduction in the heart requires gap junctions. In mammalian ventricular myocytes these consist of connexin43 (Cx43). Hearts of non-hibernating species display conduction disturbances at reduced temperatures. These may exacerbate into lethal arrhythm
Autor:
Martin Oti, Hanna Niehues, Evelyn N. Kouwenhoven, Hendrik G. Stunnenberg, Simon J. van Heeringen, Hans van Bokhoven, Huiqing Zhou, Joost Schalkwijk
Publikováno v:
EMBO Reports, 16, 863-78
EMBO Reports
EMBO Reports, 16, 7, pp. 863-78
EMBO Reports
EMBO Reports, 16, 7, pp. 863-78
Contains fulltext : 144891.pdf (Publisher’s version ) (Open Access) The transcription factor p63 plays a pivotal role in keratinocyte proliferation and differentiation in the epidermis. However, how p63 regulates epidermal genes during differentiat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::425b8e906c14191f33906b6d3cd833c8
http://hdl.handle.net/2066/144891
http://hdl.handle.net/2066/144891
Publikováno v:
Biochimica et Biophysica Acta, Gene Regulatory Mechanisms, 1849, 6, pp. 590-600
Biochimica et Biophysica Acta, Gene Regulatory Mechanisms, 1849, 590-600
Biochimica et Biophysica Acta, Gene Regulatory Mechanisms, 1849, 590-600
Contains fulltext : 149252.pdf (Publisher’s version ) (Open Access) The transcription factor p63 belongs to the p53 family and is a key regulator in epithelial commitment and development. Mutations in p63 give rise to several epithelial related dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb2ed8af3e4dbcc57403de3c32589f24
https://hdl.handle.net/2066/149252
https://hdl.handle.net/2066/149252
Autor:
Axel Visel, Elizabeth J. Leslie, Catia Attanasio, Hans van Bokhoven, Walid D. Fakhouri, Brian C. Schutte, David Huver, Julie Barrons, Len A. Pennacchio, Evelyn N. Kouwenhoven, Huiqing Zhou, Têmis Maria Félix, Fedik Rahimov, Youssef A. Kousa, Larissa Nitschke, Jeffrey C. Murray, Renata Lúcia Leite Ferreira de Lima
Publikováno v:
Human molecular genetics
Human Molecular Genetics, 23, 10, pp. 2711-20
Human Molecular Genetics, 23, 2711-20
Human Molecular Genetics, 23, 10, pp. 2711-20
Human Molecular Genetics, 23, 2711-20
Contains fulltext : 137552.pdf (Publisher’s version ) (Open Access) DNA variation in Interferon Regulatory Factor 6 (IRF6) causes Van der Woude syndrome (VWS), the most common syndromic form of cleft lip and palate (CLP). However, an etiologic vari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b363bff6b0a9b63790d0b9dc8ea48d5
https://europepmc.org/articles/PMC3990169/
https://europepmc.org/articles/PMC3990169/
Autor:
Daniel Aberdam, Matthieu Rouleau, Huiqing Zhou, Shoham Shivtiel, Daria Putin, Evelyn N. Kouwenhoven, Zohar Wolchinsky, Eli Sprecher
Publikováno v:
Stem Cell Research, 12, 1, pp. 49-59
Stem Cell Research, 12, 49-59
Stem Cell Research, Vol 12, Iss 1, Pp 49-59 (2014)
Stem Cell Research, 12, 49-59
Stem Cell Research, Vol 12, Iss 1, Pp 49-59 (2014)
The transcription factor p63, member of the p53 gene family, encodes for two main isoforms, TAp63 and ΔNp63 with distinct functions on epithelial homeostasis and cancer. Recently, we discovered that TAp63 is essential for in vitro cardiogenesis and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d21fd32e86daabc67225c8dbddfec405