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pro vyhledávání: '"Evelyn M. Witkin"'
Autor:
Evelyn M. Witkin
Publikováno v:
Perspectives in Biology and Medicine. 40:471-478
Autor:
Evelyn M. Witkin
Publikováno v:
BioEssays. 16:437-444
'Mutation frequency decline' (MFD) was discovered about forty years ago, and described as the disappearance of a particular class of ultraviolet light-induced mutations in Escherichia coli that occurred whenever protein synthesis was briefly inhibite
Autor:
Evelyn M. Witkin
Publikováno v:
Genetics. 157:461-463
GENETICS was at a turning point in the early 1940s. The classical period had matured and was ripe for the transition to the molecular era. Geneticists had established that a gene has a precise location on a particular chromosome. They had explained t
Publikováno v:
Molecular Microbiology. 6:2815-2824
In Escherichia coli, RecA protein regulates the DNA damage-inducible survival-enhancing SOS response. Mutant allele recA730, which causes constitutive SOS expression, is lethal at high temperatures in B/r, a derivative of wild-type B, but not in K-12
Publikováno v:
Proceedings of the National Academy of Sciences. 88:11574-11578
Mutation frequency decline (MFD) is the rapid decrease in the frequency of certain induced nonsense suppressor mutations occurring when protein synthesis is transiently inhibited immediately after irradiation. MFD is abolished by mutations in the uvr
Autor:
Evelyn M. Witkin
Publikováno v:
Biochimie. 73:133-141
The role of RecA protein in the SOS response of Escherichia coli is traced from the isolation of the first recA mutant to our current understanding of the scope and regulation of this DNA damage-inducible system. In addition, possible RecA protein ac
Publikováno v:
Ciba Foundation Symposium-Mutation as a Cellular Process
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29b616440b3e68b91cf3b38206acea55
https://doi.org/10.1002/9780470719718.ch4
https://doi.org/10.1002/9780470719718.ch4
Autor:
Evelyn M. Witkin
Publikováno v:
Genetics. 170(4)
ROLLIN HOTCHKISS, the distinguished biochemist and geneticist, died last December at the age of 93. I met Rollin in the summer of 1945 in Cold Spring Harbor. He had come to take the phage course, which was being offered for the first time that year.
Autor:
Evelyn M. Witkin
Publikováno v:
Annual review of microbiology. 56
The author describes the circumstances and events that led her to begin graduate work in genetics at Columbia University in 1941 and to spend the summer of 1944 and the years 1945–1955 at the Department of Genetics of the Carnegie Institution of Wa
Autor:
V Roegner-Maniscalco, Evelyn M. Witkin
Publikováno v:
Journal of Bacteriology. 174:4166-4168
A polA12 recA718 double mutant of Escherichia coli, in which DNA polymerase I is temperature sensitive, was unable to maintain normal DNA synthesis or to form colonies on rich media at 42 degrees C. Overproduction of DnaE protein, the polymerizing al