Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Evelyn M. Molloy"'
Autor:
Ingrid Richter, Zerrin Uzum, Philipp Wein, Evelyn M. Molloy, Nadine Moebius, Timothy P. Stinear, Sacha J. Pidot, Christian Hertweck
Publikováno v:
mBio, Vol 14, Iss 6 (2023)
ABSTRACTThe phytopathogenic fungus Rhizopus microsporus harbors a bacterial endosymbiont (Mycetohabitans rhizoxinica) that produces a crucial virulence factor responsible for the characteristic symptoms of rice seedling blight. The persistence of thi
Externí odkaz:
https://doaj.org/article/0ac9d9780247406692793552e79084ad
Autor:
Philipp Wein, Katharina Dornblut, Sebastian Herkersdorf, Thomas Krüger, Evelyn M. Molloy, Axel A. Brakhage, Dirk Hoffmeister, Christian Hertweck
Publikováno v:
mBio, Vol 14, Iss 4 (2023)
ABSTRACT The soft rot pathogen Janthinobacterium agaricidamnosum causes devastating damage to button mushrooms (Agaricus bisporus), one of the most cultivated and commercially relevant mushrooms. We previously discovered that this pathogen releases t
Externí odkaz:
https://doaj.org/article/a43d816f69614a7983d9c4fbbdca3ee2
Publikováno v:
Chem. 8:2894-2897
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::858d4d3c16ff1eb4f3d7b261915b2946
https://doi.org/10.1016/j.chempr.2022.10.012
https://doi.org/10.1016/j.chempr.2022.10.012
Autor:
Lydia Seyfarth, Maria Dell, Therese Horch, Ansgar Oberheide, Kyle L. Dunbar, Jana Kumpfmüller, Romy Feldmann, Veit G Hänsch, Christian Hertweck, Evelyn M. Molloy, Hans-Dieter Arndt
Publikováno v:
Angewandte Chemie (International Ed. in English)
Clostridia coordinate many important processes such as toxin production, infection, and survival by density‐dependent communication (quorum sensing) using autoinducing peptides (AIPs). Although clostridial AIPs have been proposed to be (thio)lacton
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1da5a96dff5eb06f451d786d50cbdbfd
https://doi.org/10.1002/anie.202016378
https://doi.org/10.1002/anie.202016378
Autor:
Evelyn M. Molloy, Maria Dell, Veit G. Hänsch, Kyle L. Dunbar, Romy Feldmann, Ansgar Oberheide, Lydia Seyfarth, Jana Kumpfmüller, Therese Horch, Hans‐Dieter Arndt, Christian Hertweck
Publikováno v:
Angewandte Chemie. 133:10765-10774
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::672523387ab701f1200efb6e8035fa26
https://doi.org/10.1002/ange.202016378
https://doi.org/10.1002/ange.202016378
Autor:
Evelyn M. Molloy, Hannah Büttner, Christian Hertweck, Maria Dell, Jana Kumpfmüller, Kyle L. Dunbar
Publikováno v:
Angewandte Chemie (International Ed. in English)
Closthioamide (CTA) is a symmetric nonribosomal peptide (NRP) comprised of two diaminopropane‐linked polythioamidated monomers. CTA is biosynthesized by Ruminiclostridium cellulolyticum via an atypical NRP synthetase (NRPS)‐independent biosynthet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2564e1fbcb4ed3bbc2cb59b5bd38aa95
https://doi.org/10.1002/ange.202011741
https://doi.org/10.1002/ange.202011741
Autor:
Therese Horch, Evelyn M. Molloy, Florian Bredy, Veit G. Haensch, Kirstin Scherlach, Kyle L. Dunbar, Jonathan Franke, Christian Hertweck
Publikováno v:
Angewandte Chemie (International ed. in English). 61(32)
Benzoxazole scaffolds feature prominently in diverse synthetic and natural product-derived pharmaceuticals. Our understanding of their bacterial biosynthesis is, however, limited to ortho-substituted heterocycles from actinomycetes. We report an over
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::282ceffa54a0bee2350599f945ed68ee
https://pubmed.ncbi.nlm.nih.gov/35656913
https://pubmed.ncbi.nlm.nih.gov/35656913
A Specialized Polythioamide-Binding Protein Confers Antibiotic Self-Resistance in Anaerobic Bacteria
Autor:
Finn Gude, Evelyn M. Molloy, Therese Horch, Maria Dell, Kyle L. Dunbar, Jana Krabbe, Michael Groll, Christian Hertweck
Understanding antibiotic resistance mechanisms is central to the development of anti-infective therapies and genomics-based drug discovery. Yet, many knowledge gaps remain regarding the resistance strategies employed against novel types of antibiotic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cd536faa8963f11d24fb74e1f9e691b
https://mediatum.ub.tum.de/1693448
https://mediatum.ub.tum.de/1693448
Publikováno v:
Angewandte Chemie (International Ed. in English)
Thioamide‐containing nonribosomal peptides (NRPs) are exceedingly rare. Recently the biosynthetic gene cluster for the thioamidated NRP antibiotic closthioamide (CTA) was reported, however, the enzyme responsible for and the timing of thioamide for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ced3e8b9b9480534b2d5e61b4b04ed8e
http://europepmc.org/articles/PMC6772006
http://europepmc.org/articles/PMC6772006
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58530 (2013)
It is becoming increasingly apparent that innovations from the "golden age" of antibiotics are becoming ineffective, resulting in a pressing need for novel therapeutics. The bacteriocin family of antimicrobial peptides has attracted much attention in
Externí odkaz:
https://doaj.org/article/8a176b389f4349b0adac4de721f442ed