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Xanomeline restores endogenous nicotinic acetylcholine receptor signaling in mouse prefrontal cortex
Publikováno v:
Neuropsychopharmacology. 48:671-682
Cholinergic synapses in prefrontal cortex are vital for attention, but this modulatory system undergoes substantial pre- and post-synaptic alterations during adulthood. To examine the integrated impact of these changes, we optophysiologically probe c
Autor:
Jonas Rybnicek, Yuxiao Chen, Milos Millic, JoAnne McLaurin, Philip De Jager, Julie Schneider, Yanling Wang, David Bennett, Shreejoy Tripathy, Daniel Felsky, Evelyn Lambe
Changes in high-affinity nicotinic acetylcholine receptors are intricately connected to neuropathology in Alzheimer’s Disease (AD). Protective and cognitive-enhancing roles for the nicotinic α5 subunit have been identified, but this gene has not b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c3e76b37c00b3a8e2cc2821f634e2b9
https://doi.org/10.21203/rs.3.rs-2011761/v1
https://doi.org/10.21203/rs.3.rs-2011761/v1