Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Evelyn K. Lambe"'
Autor:
Jonas Rybnicek, Yuxiao Chen, Milos Milic, Earvin S. Tio, JoAnne McLaurin, Timothy J. Hohman, Philip L. De Jager, Julie A. Schneider, Yanling Wang, David A. Bennett, Shreejoy Tripathy, Daniel Felsky, Evelyn K. Lambe
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Changes in high-affinity nicotinic acetylcholine receptors are intricately connected to neuropathology in Alzheimer’s Disease (AD). Protective and cognitive-enhancing roles for the nicotinic α5 subunit have been identified, but this gene
Externí odkaz:
https://doaj.org/article/f374cbbc47054ea0a3ea6f1c0e8deae1
Publikováno v:
iScience, Vol 27, Iss 2, Pp 108824- (2024)
Summary: Associating contexts with rewards depends on hippocampal circuits, with local inhibitory interneurons positioned to play an important role in shaping activity. Here, we demonstrate that the encoding of context-reward memory requires a ventra
Externí odkaz:
https://doaj.org/article/8f75e94a077c4b24a22ca007debd6a98
Autor:
Sridevi Venkatesan, Tianhui Chen, Yupeng Liu, Eric E. Turner, Shreejoy J. Tripathy, Evelyn K. Lambe
Publikováno v:
iScience, Vol 26, Iss 2, Pp 105992- (2023)
Summary: Attention depends on cholinergic excitation of prefrontal neurons but is sensitive to perturbation of α5-containing nicotinic receptors encoded by Chrna5. However, Chrna5-expressing (Chrna5+) neurons remain enigmatic, despite their potentia
Externí odkaz:
https://doaj.org/article/938146cb44344155b648b41bc1833e9a
Autor:
Daniel W. Sparks, Michael K. Tian, Derya Sargin, Sridevi Venkatesan, Katheron Intson, Evelyn K. Lambe
Publikováno v:
Frontiers in Neural Circuits, Vol 11 (2018)
Prefrontal cortex is a hub for attention processing and receives abundant innervation from cholinergic and serotonergic afferents. A growing body of evidence suggests that acetylcholine (ACh) and serotonin (5-HT) have opposing influences on tasks req
Externí odkaz:
https://doaj.org/article/dc7ad6c3c9f640d7be4510dd297bfc8d
SUMMARYAssociating contexts with rewards depends on hippocampal circuits, with local inhibitory interneurons positioned to play an important role in shaping activity. Here, we hypothesize that the encoding of context-reward memory requires a ventral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8daa2a9d8f790e7351d1723432292c04
https://doi.org/10.1101/2023.04.27.538595
https://doi.org/10.1101/2023.04.27.538595
Autor:
Ashlea A. Morgan, Nuno D. Alves, Gregory S. Stevens, Tamanna T. Yeasmin, Alexandra Mackay, Saige Power, Derya Sargin, Carla Hanna, Arwa L. Adib, Annette Ziolkowski-Blake, Evelyn K. Lambe, Mark S. Ansorge
Publikováno v:
bioRxiv
The medial prefrontal cortex (mPFC) regulates cognitive flexibility and emotional behavior. Neurons that release serotonin project to the mPFC, and serotonergic drugs influence emotion and cognition. Yet, the specific roles of endogenous serotonin re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3a73827ec9515913085af7e13d7e84b
https://europepmc.org/articles/PMC10081203/
https://europepmc.org/articles/PMC10081203/
Autor:
Jonas Rybnicek, Yuxiao Chen, Milos Milic, JoAnne McLaurin, Phillip De Jager, Julie A Schneider, Yanling Wang, David A Bennett, Shreejoy Tripathy, Daniel Felsky, Evelyn K Lambe
Changes in high-affinity nicotinic acetylcholine receptors are intricately connected to neuropathology in Alzheimer's Disease (AD). Protective and cognitive-enhancing roles for the nicotinic α5 subunit have been identified, but this gene has not bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4662afbb7e13521f8b07b6c3fad07a63
https://doi.org/10.1101/2022.05.03.490491
https://doi.org/10.1101/2022.05.03.490491
Publikováno v:
eLife, Vol 5 (2016)
The activity of serotonin (5-HT) neurons is critical for mood regulation. In a mouse model of chronic social isolation, a known risk factor for depressive illness, we show that 5-HT neurons in the dorsal raphe nucleus are less responsive to stimulati
Externí odkaz:
https://doaj.org/article/d4f625d8ad2f4c76850be009c1bb38cd
Publikováno v:
Frontiers in Neural Circuits, Vol 9 (2015)
Externí odkaz:
https://doaj.org/article/90950194e9da48fa881fbf0e41253849
Autor:
Ibis M. Agosto-Marlin, Nailyam Nasirova, Lely A. Quina, Evelyn K. Lambe, Eric E. Turner, Jan-Marino Ramirez
Publikováno v:
J Comp Neurol
Cholinergic transmission shapes the maturation of glutamatergic circuits, yet the developmental sources of acetylcholine have not been systematically explored. Here we have used Cre-recombinase mediated genetic labeling to identify and map both matur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6465787106096442e9dedb3a80d5cabf
https://doi.org/10.1002/cne.24753
https://doi.org/10.1002/cne.24753