Predicting remission after internet-delivered psychotherapy in patients with depression using machine learning and multi-modal data

Autor: John Wallert, Julia Boberg, Viktor Kaldo, David Mataix-Cols, Oskar Flygare, James J. Crowley, Matthew Halvorsen, Fehmi Ben Abdesslem, Magnus Boman, Evelyn Andersson, Nils Hentati Isacsson, Ekaterina Ivanova, Christian Rück

Publikováno v: Translational Psychiatry, Vol 12, Iss 1, Pp 1-10 (2022)

Abstract This study applied supervised machine learning with multi-modal data to predict remission of major depressive disorder (MDD) after psychotherapy. Genotyped adult patients (n = 894, 65.5% women, age 18–75 years) diagnosed with mild-to-moder

Externí odkaz: https://doaj.org/article/cb4aae8082df48b195f13d7e60706da2

Genome-wide association study of patients with a severe major depressive episode treated with electroconvulsive therapy

Autor: Cynthia M. Bulik, Robert Karlsson, Axel Nordenskjöld, Evelyn Andersson, Erik Pålsson, Yi Lu, Julia Boberg, Anders Juréus, Patrick F. Sullivan, Christian Rück, Caitlin C. Clements, Nancy L. Pedersen, Mikael Landén

Publikováno v: Molecular Psychiatry. 26:2429-2439

Although large genome-wide association studies (GWAS) of major depressive disorder (MDD) have identified many significant loci, the SNP-based heritability remains notably low, which might be due to etiological heterogeneity in existing samples. Here,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::690441d7583affe58166066ba4f720b7
https://doi.org/10.1038/s41380-020-00984-0

Predictors of Symptomatic Change and Adherence in Internet-Based Cognitive Behaviour Therapy for Social Anxiety Disorder in Routine Psychiatric Care.

Autor: Samir El Alaoui, Brjánn Ljótsson, Erik Hedman, Viktor Kaldo, Evelyn Andersson, Christian Rück, Gerhard Andersson, Nils Lindefors

Publikováno v: PLoS ONE, Vol 10, Iss 4, p e0124258 (2015)

ObjectiveA central goal of health care is to improve patient outcomes. Although several studies have demonstrated the effectiveness of therapist guided internet-based cognitive behaviour therapy (ICBT) for social anxiety disorder (SAD), a significant

Externí odkaz: https://doaj.org/article/e147a0c99c304640aaa89b8cacb2be88

Predicting remission after internet-delivered psychotherapy in patients with depression using machine learning and multi-modal data

Autor: John Wallert, Julia Boberg, Viktor Kaldo, David Mataix-Cols, Oskar Flygare, James J. Crowley, Matthew Halvorsen, Fehmi Ben Abdesslem, Magnus Boman, Evelyn Andersson, Nils Hentati Isacsson, Ekaterina Ivanova, Christian Rück

Publikováno v: Translational psychiatry. 12(1)

This study applied supervised machine learning with multi-modal data to predict remission of major depressive disorder (MDD) after psychotherapy. Genotyped adult patients (n = 894, 65.5% women, age 18–75 years) diagnosed with mild-to-moderate MDD a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::257166c901ad10dc858886e2cef0c5cb
https://pubmed.ncbi.nlm.nih.gov/36050305

Therapygenetic effects of 5-HTTLPR on cognitive-behavioral therapy in anxiety disorders: A meta-analysis

Autor: Sylvia Helbig-Lang, Jiaxi Lin, Gerhard Andersson, Thalia C. Eley, Katharina Domschke, Susanna Roberts, Paul Pauli, Jennifer L. Hudson, Jan Bergström, Jan Richter, Kathryn J. Lester, Alexander L. Gerlach, Alfons O. Hamm, Ulrike Lueken, Winfried Rief, Christiane Thiel, Volker Arolt, Andreas Reif, Tina B. Lonsdorf, Heike Weber, Koen Schruers, Miriam A. Schiele, Hans-Ulrich Wittchen, Evelyn Andersson, T. Lang, Christian Rück, Nils Lindefors, Per Carlbring, Georg W. Alpers, Gabriel Esquivel, Tomas Furmark

Publikováno v: European Neuropsychopharmacology, 44, 105-120. Elsevier
Schiele, M A, Reif, A, Lin, J, Alpers, G W, Andersson, E, Andersson, G, Arolt, V, Bergström, J, Carlbring, P, Eley, T C, Esquivel, G, Furmark, T, Gerlach, A L, Hamm, A, Helbig-Lang, S, Hudson, J L, Lang, T, Lester, K J, Lindefors, N, Lonsdorf, T B, Pauli, P, Richter, J, Rief, W, Roberts, S, Rück, C, Schruers, K R J, Thiel, C, Wittchen, H U, Domschke, K, Weber, H & Lueken, U 2021, ' Therapygenetic effects of 5-HTTLPR on cognitive-behavioral therapy in anxiety disorders : A meta-analysis ', European Neuropsychopharmacology, vol. 44, pp. 105-120 . https://doi.org/10.1016/j.euroneuro.2021.01.004

There is a recurring debate on the role of the serotonin transporter gene linked polymorphic region (5-HTTLPR) in the moderation of response to cognitive behavioral therapy (CBT) in anxiety disorders. Results, however, are still inconclusive. We here

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::355ccf57f07705001f3910e50967192e
https://cris.maastrichtuniversity.nl/en/publications/fedd3c57-3ac1-4796-9697-84222d108383