Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Eveline S.J.M. de Bont"'
Autor:
Fieke W. Hoff, Anneke D. van Dijk, Yihua Qiu, Chenyue W. Hu, Rhonda E. Ries, Andrew Ligeralde, Gaye N. Jenkins, Robert B. Gerbing, Alan S. Gamis, Richard Aplenc, E. Anders Kolb, Todd A. Alonzo, Soheil Meshinchi, Amina A. Qutub, Eveline S.J.M. de Bont, Terzah M. Horton, Steven M. Kornblau
Publikováno v:
Haematologica, Vol 107, Iss 10 (2022)
Pediatric acute myeloid leukemia (AML) remains a fatal disease for at least 30% of patients, stressing the need for improved therapies and better risk stratification. As proteins are the unifying feature of (epi)genetic and environmental alterations,
Externí odkaz:
https://doaj.org/article/ec910a7b013b405a849aaa5ec9509aa0
Autor:
Walderik W. Zomerman, Sabine L.A. Plasschaert, Siobhan Conroy, Frank J. Scherpen, Tiny G.J. Meeuwsen-de Boer, Harm J. Lourens, Sergi Guerrero Llobet, Marlinde J. Smit, Lorian Slagter-Menkema, Annika Seitz, Corrie E.M. Gidding, Esther Hulleman, Pieter Wesseling, Lisethe Meijer, Leon C. van Kempen, Anke van den Berg, Daniël O. Warmerdam, Frank A.E. Kruyt, Floris Foijer, Marcel A.T.M. van Vugt, Wilfred F.A. den Dunnen, Eelco W. Hoving, Victor Guryev, Eveline S.J.M. de Bont, Sophia W.M. Bruggeman
Publikováno v:
Cell Reports, Vol 22, Iss 12, Pp 3206-3216 (2018)
Summary: The brain cancer medulloblastoma consists of different transcriptional subgroups. To characterize medulloblastoma at the phosphoprotein-signaling level, we performed high-throughput peptide phosphorylation profiling on a large cohort of SHH
Externí odkaz:
https://doaj.org/article/29d5a08e9ade4e27a193d73891378371
Autor:
Natasha K.A. van Eijkelenburg, Mareike Rasche, Essam Ghazaly, Michael N. Dworzak, Thomas Klingebiel, Claudia Rossig, Guy Leverger, Jan Stary, Eveline S.J.M. De Bont, Dana A. Chitu, Yves Bertrand, Benoit Brethon, Brigitte Strahm, Inge M. van der Sluis, Gertjan J.L. Kaspers, Dirk Reinhardt, C. Michel Zwaan
Publikováno v:
Haematologica, Vol 103, Iss 9 (2018)
Survival in children with relapsed/refractory acute myeloid leukemia is unsatisfactory. Treatment consists of one course of fludarabine, cytarabine and liposomal daunorubicin, followed by fludarabine and cytarabine and stem-cell transplantation. Stud
Externí odkaz:
https://doaj.org/article/e83b67ad53a44206b03414604c18aca2
Autor:
Hendrik J.M. de Jonge, Peter J.M. Valk, Eveline S.J.M. de Bont, Jan Jacob Schuringa, Gert Ossenkoppele, Edo Vellenga, Gerwin Huls
Publikováno v:
Haematologica, Vol 96, Iss 9 (2011)
Background High white blood cell count at presentation is an unfavorable prognostic factor for treatment outcome in intermediate cytogenetic risk acute myeloid leukemia. Since the impact of white blood cell count on outcome of subgroups defined by th
Externí odkaz:
https://doaj.org/article/6dc65a4239c04416a028e43ece5aa3f9
Autor:
Iris H.I.M. Hollink, Marry M. van den Heuvel-Eibrink, Susan T.C.J.M. Arentsen-Peters, Martin Zimmermann, Justine K. Peeters, Peter J.M. Valk, Brian V. Balgobind, Edwin Sonneveld, Gertjan J.L. Kaspers, Eveline S.J.M. de Bont, Jan Trka, Andre Baruchel, Ursula Creutzig, Rob Pieters, Dirk Reinhardt, C. Michel Zwaan
Publikováno v:
Haematologica, Vol 96, Iss 3 (2011)
Background Dysfunctioning of CCAAT/enhancer binding protein α (C/EBPα) in acute myeloid leukemia can be caused, amongst others, by mutations in the encoding gene (CEBPA) and by promoter hypermethylation. CEBPA-mutated acute myeloid leukemia is asso
Externí odkaz:
https://doaj.org/article/c6cc1fc259804a97b57491fef67a1b85
Autor:
Terzah M. Horton, Steven M. Kornblau, Amina A. Qutub, Eveline S.J.M. de Bont, Michael E. Scheurer, Suk-Young Yoo, Andrew Ligeralde, Yihua Qiu, Chenyue W. Hu, Fieke W. Hoff
Pediatric acute lymphoblastic leukemia (ALL) is the most common pediatric malignancy, and the second leading cause of pediatric cancer–related death in developed countries. While the cure rate for newly diagnosed ALL is excellent, the genetic heter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4acda497c54e04114bb318d8633d9e3
https://doi.org/10.1158/1541-7786.c.6540292.v1
https://doi.org/10.1158/1541-7786.c.6540292.v1
Autor:
Eveline S.J.M. de Bont, Jan Jacob Schuringa, Willem A. Kamps, Tiny Meeuwsen-de Boer, Kim R. Kampen, Arja ter Elst, Alida C. Weidenaar
Although most children with acute myeloid leukemia (AML) achieve complete remission, the relapse rate is 30% to 40%. Because it is thought that leukemia-initiating cells (LIC) are responsible for AML relapses, targeting these cells might improve outc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ba60250d51f4f14df6d8a8b268685cb
https://doi.org/10.1158/1541-7786.c.6541785
https://doi.org/10.1158/1541-7786.c.6541785
Autor:
Eveline S.J.M. de Bont, Jan Jacob Schuringa, Willem A. Kamps, Tiny Meeuwsen-de Boer, Kim R. Kampen, Arja ter Elst, Alida C. Weidenaar
XLSX file - 21K, Specific primers for RT-PCR.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cebe235894755ee4644295d4229de5a
https://doi.org/10.1158/1541-7786.22517631.v1
https://doi.org/10.1158/1541-7786.22517631.v1
Autor:
Eveline S.J.M. de Bont, Jan Jacob Schuringa, Willem A. Kamps, Tiny Meeuwsen-de Boer, Kim R. Kampen, Arja ter Elst, Alida C. Weidenaar
PDF file - 85K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2698d46afdac020af8400ebc650702a6
https://doi.org/10.1158/1541-7786.22517634.v1
https://doi.org/10.1158/1541-7786.22517634.v1
Autor:
Eveline S.J.M. de Bont, Jan Jacob Schuringa, Willem A. Kamps, Tiny Meeuwsen-de Boer, Kim R. Kampen, Arja ter Elst, Alida C. Weidenaar
PDF file - 147K, Effect of VEGFA-addition, Bevacizumab, specific VEGFR-inhibitor and MK2206 on CD34+ sorted pediatric AML cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::329c2e2072c0b41869aa5def903c733e
https://doi.org/10.1158/1541-7786.22517637.v1
https://doi.org/10.1158/1541-7786.22517637.v1