Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Eveline A. Bouwens"'
Autor:
Eduard H.T.M. Ebberink, Eveline A.M. Bouwens, Esther Bloem, Mariëtte Boon-Spijker, Maartje van den Biggelaar, Jan Voorberg, Alexander B. Meijer, Koen Mertens
Publikováno v:
Haematologica, Vol 102, Iss 4 (2017)
Factor VIII C-domains are believed to have specific functions in cofactor activity and in interactions with von Willebrand factor. We have previously shown that factor VIII is co-targeted with von Willebrand factor to the Weibel-Palade bodies in bloo
Externí odkaz:
https://doaj.org/article/249218b0d5384c50aed37bce608c5f9a
Autor:
Maartje van den Biggelaar, Eveline A.M. Bouwens, Neeltje A. Kootstra, Robert P. Hebbel, Jan Voorberg, Koen Mertens
Publikováno v:
Haematologica, Vol 94, Iss 5 (2009)
Background Gene therapy provides an attractive alternative for protein replacement therapy in hemophilia A patients. Recent studies have shown the potential benefit of directing factor (F)VIII gene delivery to cells that also express its natural carr
Externí odkaz:
https://doaj.org/article/f9e7283f999c4472951cf03fe65dc90d
Publikováno v:
Journal of Thrombosis and Haemostasis. 11:242-253
The protein C pathway provides multiple important functions to maintain a regulated balance between haemostasis and host defence systems in response to vascular and inflammatory injury. The anticoagulant protein C pathway is designed to regulate coag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92a14a42976076c50a29abd58594062d
https://doi.org/10.1111/jth.12247
https://doi.org/10.1111/jth.12247
Autor:
Eveline A. Bouwens, Laurent Burnier, Ranjeet Kumar Sinha, John H. Griffin, Laurent O. Mosnier
Publikováno v:
Blood
Activated protein C (APC) exerts endothelial cytoprotective actions that require protease-activated receptor 1 (PAR1), whereas thrombin acting via PAR1 causes endothelial disruptive, proinflammatory actions. APC's activities, but not thrombin's, requ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee226cafc5a45b3d50efeb43a106f5d6
Autor:
Louise Turner, Thor G. Theander, Monique F. Stins, José Hermida, Eveline A. Bouwens, Ibai Tamayo, Christian W. Wang, Thomas Lavstsen, Laurent O. Mosnier, Jens E.V. Petersen
Publikováno v:
Thromb Haemost
SummaryThe Endothelial Protein C receptor (EPCR) is essential for the anticoagulant and cytoprotective functions of the Protein C (PC) system. Selected variants of the malaria parasite protein, Plasmodium falciparum Erythrocyte Membrane Protein 1 (Pf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3469dbd20125c66e06f88921eabfb6e9
https://europepmc.org/articles/PMC8142631/
https://europepmc.org/articles/PMC8142631/
Publikováno v:
Thrombosis and haemostasis. 114(6)
SummaryThe protein C (PC) system conveys beneficial anticoagulant and cytoprotective effects in numerous in vivo disease models. The endothelial protein C receptor (EPCR) plays a central role in these pathways as cofactor for PC activation and by enh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e038b3bd200f119d55388112550d0dd9
https://pubmed.ncbi.nlm.nih.gov/26272345
https://pubmed.ncbi.nlm.nih.gov/26272345
Autor:
José Hermida, Monique F. Stins, Eveline A. Bouwens, Louis Turner, Jens E.V. Petersen, Ibai Tamayo, Christian W. Wang, Thomas Lavstsen, Laurent O. Mosnier, Thor G. Theander
Publikováno v:
ResearcherID
Introduction: The endothelial protein C receptor (EPCR) is essential for the functions of the protein C system. EPCR enhances the activation of protein C and facilitates the activation of protease activated receptors 1 and 3 by activated protein C (A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da7d5c11d6fcb17880b80f732df7a12b
https://doi.org/10.1182/blood.v124.21.577.577
https://doi.org/10.1182/blood.v124.21.577.577
Autor:
John H. Griffin, Eveline A. Bouwens, Laurent O. Mosnier, Ranjeet Kumar Sinha, Laurent Burnier
Publikováno v:
Blood. 120:497-497
Abstract 497 Activated protein C (APC) exerts cytoprotective activities on vascular endothelium that require protease-activated receptor 1 (PAR1) whereas thrombin acting via PAR1 causes endothelial disruptive, proinflammatory actions. Last year our l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c25c2be7771d8ad9434e158c3ff5fab
https://doi.org/10.1182/blood.v120.21.497.497
https://doi.org/10.1182/blood.v120.21.497.497