Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Eveline, Snelders"'
Autor:
Ben Auxier, Alfons J M Debets, Felicia Adelina Stanford, Johanna Rhodes, Frank M Becker, Francisca Reyes Marquez, Reindert Nijland, Paul S Dyer, Matthew C Fisher, Joost van den Heuvel, Eveline Snelders
Publikováno v:
PLoS Biology, Vol 21, Iss 9, p e3002278 (2023)
Sexual reproduction involving meiosis is essential in most eukaryotes. This produces offspring with novel genotypes, both by segregation of parental chromosomes as well as crossovers between homologous chromosomes. A sexual cycle for the opportunisti
Externí odkaz:
https://doaj.org/article/6466b45940c740e1b63f9aee85743c67
Autor:
Jianhua Zhang, Paul E. Verweij, Antonius J. M. M. Rijs, Alfons J. M. Debets, Eveline Snelders
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2022)
With population genetic evidence of recombination ongoing in the natural Aspergillus fumigatus population and a sexual cycle demonstrated in the laboratory the question remained what the natural niche for A. fumigatus sex is. Composting plant-waste m
Externí odkaz:
https://doaj.org/article/536f7872b65e4887bcb61ed53772757f
Autor:
Sijmen E. Schoustra, Alfons J.M. Debets, Antonius J.M.M. Rijs, Jianhua Zhang, Eveline Snelders, Peter C. Leendertse, Willem J.G. Melchers, Anton G. Rietveld, Bas J. Zwaan, Paul E. Verweij
Publikováno v:
Emerging Infectious Diseases, Vol 25, Iss 7, Pp 1347-1353 (2019)
Azole resistance is a major concern for treatment of infections with Aspergillus fumigatus. Environmental resistance selection is a main route for Aspergillus spp. to acquire azole resistance. We investigated the presence of environmental hotspots fo
Externí odkaz:
https://doaj.org/article/770107f78d774edc881ad9a2470b4788
Autor:
Tobias Engel, Paul E. Verweij, Joost van den Heuvel, Dechen Wangmo, Jianhua Zhang, Alfons J.M. Debets, Eveline Snelders
Publikováno v:
ERJ Open Research, Vol 6, Iss 4 (2020)
Aspergillus fumigatus is a saprobic fungus that causes a range of pulmonary diseases, some of which are characterised by fungal persistence such as is observed in cystic fibrosis (CF) patients. Creation of genetic variation is critical for A. fumigat
Externí odkaz:
https://doaj.org/article/de3d9b80d4fd468483906cd11dd6106d
Publikováno v:
Emerging Infectious Diseases, Vol 25, Iss 1, Pp 176-178 (2019)
We investigated azole resistance in Aspergillus fumigatus in a tertiary reference hospital in the Netherlands during 1994–2016. The 5-year patient-adjusted proportion of resistance increased from 0.79% for 1996–2001 to 4.25% for 2002–2006, 7.17
Externí odkaz:
https://doaj.org/article/338bff355b5842c59b519610e2ac166b
Publikováno v:
Journal of Fungi, Vol 7, Iss 8, p 599 (2021)
In order to successfully infect or colonize human hosts or survive changing environments, Aspergillus fumigatus needs to adapt through genetic changes or phenotypic plasticity. The genomic changes are based on the capacity of the fungus to produce ge
Externí odkaz:
https://doaj.org/article/b1c87bcc885a45ed9e5e313aa050b52a
Autor:
Ben Auxier, Jianhua Zhang, Francisca Reyes Marquez, Kira Senden, Joost van den Heuvel, Duur K. Aanen, Eveline Snelders, Alfons J.M. Debets
In fungi, a phenomenon termed heterokaryon incompatibility restricts hyphal fusion to occur within an individual since fusion between individuals leads to cell death. Generally, the genes involved are found to be under balancing selection from negati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f610a60c00cb621b6994cbc2bea619e5
https://doi.org/10.1101/2022.11.25.517501
https://doi.org/10.1101/2022.11.25.517501
Triazole resistance in the airborne human fungal pathogenAspergillus fumigatusis a significant human health problem as the environmental use of triazoles has selected for cross-resistance to life-saving clinical triazoles in medicine. Despite the env
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6af9d6a30532819b0480cd3202b93b8
https://doi.org/10.1101/2022.11.03.515058
https://doi.org/10.1101/2022.11.03.515058
Autor:
Jianhua Zhang, Eveline Snelders, Bas J. Zwaan, Sijmen E. Schoustra, Jacques F. Meis, Karin van Dijk, Ferry Hagen, Martha T. van der Beek, Greetje A. Kampinga, Jan Zoll, Willem J. G. Melchers, Paul E. Verweij, Alfons J. M. Debets
Publikováno v:
mBio, Vol 8, Iss 3 (2017)
ABSTRACT This study investigated the dynamics of Aspergillus fumigatus azole-resistant phenotypes in two compost heaps with contrasting azole exposures: azole free and azole exposed. After heat shock, to which sexual but not asexual spores are highly
Externí odkaz:
https://doaj.org/article/946ea22cd3ba44e9814688dad8dc166a
Autor:
Paul E. Verweij, Alfons J. M. Debets, Tobias Engel, Joost van den Heuvel, Jianhua Zhang, Eveline Snelders, Dechen Wangmo
Publikováno v:
ERJ Open Research 6 (2020) 4
ERJ Open Research, 6, 4
ERJ Open Research, Vol 6, Iss 4 (2020)
ERJ Open Research, 6
ERJ Open Research, 6(4)
ERJ Open Research, 6, 4
ERJ Open Research, Vol 6, Iss 4 (2020)
ERJ Open Research, 6
ERJ Open Research, 6(4)
Aspergillus fumigatusis a saprobic fungus that causes a range of pulmonary diseases, some of which are characterised by fungal persistence such as is observed in cystic fibrosis (CF) patients. Creation of genetic variation is critical forA. fumigatus