Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Evelina Folkesson"'
Autor:
B. Cristoffer Sakshaug, Evelina Folkesson, Tonje Husby Haukaas, Torkild Visnes, Åsmund Flobak
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-18 (2023)
Abstract While chemotherapy alone or in combination with radiotherapy and surgery are important modalities in the treatment of colorectal cancer, their widespread use is not paired with an abundance of diagnostic tools to match individual patients wi
Externí odkaz:
https://doaj.org/article/53feb7283f5d42c5b146b8c8dd6112ab
Autor:
Åsmund Flobak, John Zobolas, Miguel Vazquez, Tonje S. Steigedal, Liv Thommesen, Asle Grislingås, Barbara Niederdorfer, Evelina Folkesson, Martin Kuiper
Publikováno v:
Frontiers in Systems Biology, Vol 3 (2023)
Treatment with combinations of drugs carries great promise for personalized therapy for a variety of diseases. We have previously shown that synergistic combinations of cancer signaling inhibitors can be identified based on a logical framework, by ma
Externí odkaz:
https://doaj.org/article/aaa85615ca6e41e4903f1202121a5938
Publikováno v:
Frontiers in Systems Biology, Vol 3 (2023)
Drug combinations have been proposed to combat drug resistance in cancer, but due to the large number of possible drug targets, in vitro testing of all possible combinations of drugs is challenging. Computational models of a disease hold great promis
Externí odkaz:
https://doaj.org/article/d9ff8c0e77264f3ab637172d892f4cc1
Autor:
Evelina Folkesson, Barbara Niederdorfer, Vu To Nakstad, Liv Thommesen, Geir Klinkenberg, Astrid Lægreid, Åsmund Flobak
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-2 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/ee22fedb649e487bb2c164209c05ebd1
Logical modeling: Combining manual curation and automated parameterization to predict drug synergies
Autor:
Grislingås A, John Zobolas, Tonje S. Steigedal, Miguel Vazquez, Åsmund Flobak, Liv Thommesen, Barbara Niederdorfer, Evelina Folkesson, Martin Kuiper
Treatment with drug combinations carries great promise for personalized therapy. We have previously shown that drug synergies targeting cancer can manually be identified based on a logical framework. We now demonstrate how automated adjustments of mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c07847d5dcad23a10af7472153d368e9
https://doi.org/10.1101/2021.06.28.450165
https://doi.org/10.1101/2021.06.28.450165
Autor:
Barbara Niederdorfer, Geir Klinkenberg, Vu To Nakstad, Åsmund Flobak, Astrid Lægreid, Evelina Folkesson, Liv Thommesen
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-2 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-2 (2020)
Drug combinations have been proposed to combat drug resistance, but putative treatments are challenged by low bench-to-bed translational efficiency. To explore the effect of cell culture format and readout methods on identification of synergistic dru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8035062a4ad07f70821f80f4a891e3c9
http://europepmc.org/articles/PMC7688975
http://europepmc.org/articles/PMC7688975
Autor:
Åsmund Flobak, Astrid Lægreid, Barbara Niederdorfer, Liv Thommesen, Evelina Folkesson, Geir Klinkenberg, Vu To Nakstad
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Drug combinations have been proposed to combat drug resistance, but putative treatments are challenged by low bench-to-bed translational efficiency. To explore the effect of cell culture format and readout methods on identification of synergistic dru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dac3b8e6d6ed9edb981d9b977fc6d18
https://doi.org/10.1038/s41598-020-68441-0
https://doi.org/10.1038/s41598-020-68441-0