Effluent and serum protein N-glycosylation is associated with inflammation and peritoneal membrane transport characteristics in peritoneal dialysis patients

Autor: Evelina Ferrantelli, Karima Farhat, Agnes L. Hipgrave Ederveen, Karli R. Reiding, Robert H. J. Beelen, Frans J. van Ittersum, Manfred Wuhrer, Viktoria Dotz

Publikováno v: Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)

Abstract Mass spectrometric glycomics was used as an innovative approach to identify biomarkers in serum and dialysate samples from peritoneal dialysis (PD) patients. PD is a life-saving treatment worldwide applied in more than 100,000 patients suffe

Externí odkaz: https://doaj.org/article/c3bd45e874fd4b6eb24f1f6192150d5e

Effluent and serum protein N-glycosylation is associated with inflammation and peritoneal membrane transport characteristics in peritoneal dialysis patients

Autor: Agnes L. Hipgrave Ederveen, Viktoria Dotz, Evelina Ferrantelli, Manfred Wuhrer, Frans J. van Ittersum, Karli R. Reiding, Karima Farhat, Robert H.J. Beelen

Publikováno v: Scientific Reports, 8
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific reports, 8(1). Nature Publishing Group
Scientific Reports, 8(1):979, 1-11. Nature Publishing Group
Ferrantelli, E, Farhat, K, Ederveen, A L H, Reiding, K R, Beelen, R H J, Van Ittersum, F J, Wuhrer, M & Dotz, V 2018, ' Effluent and serum protein N-glycosylation is associated with inflammation and peritoneal membrane transport characteristics in peritoneal dialysis patients ', Scientific Reports, vol. 8, no. 1, 979 . https://doi.org/10.1038/s41598-018-19147-x
Ferrantelli, E, Farhat, K, Ederveen, A L H, Reiding, K R, Beelen, R H J, Van Ittersum, F J, Wuhrer, M & Dotz, V 2018, ' Effluent and serum protein N-glycosylation is associated with inflammation and peritoneal membrane transport characteristics in peritoneal dialysis patients ', Scientific Reports, vol. 8, no. 1, 979, pp. 1-11 . https://doi.org/10.1038/s41598-018-19147-x
Scientific Reports, 8(1):979. Nature Publishing Group

Mass spectrometric glycomics was used as an innovative approach to identify biomarkers in serum and dialysate samples from peritoneal dialysis (PD) patients. PD is a life-saving treatment worldwide applied in more than 100,000 patients suffering from

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4de4dd11b4d14d72bf91f8b8531256cc
https://research.vu.nl/en/publications/e39e1092-48ad-4c76-9565-35d6073a6a2d

The dipeptide alanyl-glutamine ameliorates peritoneal fibrosis and attenuates IL-17 dependent pathways during peritoneal dialysis

Autor: Eelco D. Keuning, Manuel López-Cabrera, Evelina Ferrantelli, Marc Vila Cuenca, Georgios Liappas, Thomas L. Foster, Robert H.J. Beelen, Marc G. Vervloet

Publikováno v: Kidney International, 89(3), 625-635. Nature Publishing Group
Ferrantelli, E, Liappas, G, Cuenca, M V, Keuning, E D, Foster, T L, Vervloet, M G, Lopez-Cabrera, M & Beelen, R H J 2016, ' The dipeptide alanyl-glutamine ameliorates peritoneal fibrosis and attenuates IL-17 dependent pathways during peritoneal dialysis ', Kidney International, vol. 89, no. 3, pp. 625-635 . https://doi.org/10.1016/j.kint.2015.12.005

Peritoneal dialysis (PD) can result in chronic inflammation and progressive peritoneal membrane damage. Alanyl-Glutamine (Ala-Gln), a dipeptide with immunomodulatory effects, improved resistance of mesothelial cells to PD fluids. Recently, interleuki

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac68f44ba1e9b41dc34eb02275f26fa5
https://doi.org/10.1016/j.kint.2015.12.005

Differences in peritoneal response after exposure to low-GDP bicarbonate/lactate-buffered dialysis solution compared to conventional dialysis solution in a uremic mouse model

Autor: W. Talhout, Evelina Ferrantelli, Marc G. Vervloet, P. M. ter Wee, F. J. van Ittersum, M. Vila Cuenca, Robert H.J. Beelen, Nanne J. Paauw, Eelco D. Keuning

Publikováno v: Vila Cuenca, M, Keuning, E D, Talhout, W, Paauw, N J, van Ittersum, F J, ter Wee, P M, Beelen, R H J, Vervloet, M G & Ferrantelli, E 2018, ' Differences in peritoneal response after exposure to low-GDP bicarbonate/lactate-buffered dialysis solution compared to conventional dialysis solution in a uremic mouse model ', INTERNATIONAL UROLOGY AND NEPHROLOGY, vol. 50, no. 6, pp. 1151-1161 . https://doi.org/10.1007/s11255-018-1872-3
International Urology and Nephrology
INTERNATIONAL UROLOGY AND NEPHROLOGY, 50(6), 1151-1161. Springer Netherlands

Background: Long-term exposure of conventional peritoneal dialysis (PD) fluid is associated with structural membrane alterations and technique failure. Previously, it has been shown that infiltrating IL-17-secreting CD4+T cells and pro-fibrotic M2 ma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b091970e92332874862497cf4e170041
https://research.vumc.nl/en/publications/84b2a920-0c71-482a-b2ec-0bed55f5480d

EUROPEAN TRAINING AND RESEARCH IN PERITONEAL DIALYSIS: SCIENTIFIC OBJECTIVES, TRAINING, IMPLEMENTATION AND IMPACT OF THE PROGRAMME

Autor: Evelina Ferrantelli, Tanja van Wier-van der Schaaf, Thomas L. Foster, Robert H.J. Beelen

Publikováno v: Journal of Renal Care. 40:34-39

SUMMARY Background Peritoneal dialysis (PD) offers many advantages over hospital-based haemodialysis, including better quality of life. Despite this, there is a general under-utilisation of PD in Europe, which, to some extent, can be attributed to a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7ffe25787cf755cdb63b532532e526f7
https://doi.org/10.1002/jorc.12041