Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Evelina Bertolotti"'
Autor:
Evelina Bertolotti, Dorit Hoffmann, Antonella Comitato, Andreas Rentsch, Frank Schwede, Friedrich W. Herberg, Philipp Henning, Eleonora Vighi, Valeria Marigo, Hans-Gottfried Genieser, Daniela Bertinetti
Publikováno v:
Oncotarget
Melanoma is one of the most aggressive cancers and displays high resistance to conventional chemotherapy underlining the need for new therapeutic strategies. The cGMP/PKG signaling pathway was detected in melanoma cells and shown to reduce migration,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1b20bee55b01a51afffe5245879533a
http://europepmc.org/articles/PMC5797051
http://europepmc.org/articles/PMC5797051
Publikováno v:
Journal of Morphology. 277:888-895
In most vertebrates, the regenerative capacity to restore lost/damage tissues to original structure and functionality decreases at some time during ontogenesis. To evaluate the role of the acquired immunity in the decline of regenerative potential, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::782a4040959b33568bbc4e4177e567c7
https://doi.org/10.1002/jmor.20542
https://doi.org/10.1002/jmor.20542
Autor:
Andreas Rentsch, Manoj Kulkarni, Dorit Hoffmann, Marius Ueffing, Dragana Trifunović, François Paquet-Durand, Angelique van den Heuvel, Patricia Veiga-Crespo, Thomas Euler, Eleonora Vighi, Arie Reijerkerk, Torsten Strasser, Pieter J. Gaillard, Frank Schwede, Valeria Marigo, Evelina Bertolotti, Per Ekström, Tobias Peters, Ayse Sahaboglu, Hans G. Genieser
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Development of treatments for hereditary degeneration of the retina (RD) is hampered by the vast genetic heterogeneity of this group of diseases and by the delivery of the drug to an organ protected by the blood–retina barrier. Here, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d3dedb4808a760437fa5d0992b44282
https://pubmed.ncbi.nlm.nih.gov/29531030
https://pubmed.ncbi.nlm.nih.gov/29531030
Autor:
Dorit Hoffmann, Antonella Comitato, Andreas Rentsch, Frank Schwede, Valeria Marigo, Hans-Gottfried Genieser, Evelina Bertolotti, Eleonora Vighi
Activation of the cGMP-dependent protein kinase G (PKG) can inhibit growth and/or induce apoptosis in colon cancer. In this study we evaluated the effects on cell viability, cell death and proliferation of novel dimeric cGMP analogues, compared to a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6720cc7ef5afc701848d11538e57aa8
https://hdl.handle.net/11380/1151591
https://hdl.handle.net/11380/1151591
Publikováno v:
Journal of Morphology. 274:956-964
Xenopus froglets can perfectly heal skin wounds without scarring. To explore whether this capacity is maintained as development proceeds, we examined the cellular responses during the repair of skin injury in 8- and 15-month-old Xenopus laevis. The m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10805da176573ed4ab70813f8713f746
https://doi.org/10.1002/jmor.20155
https://doi.org/10.1002/jmor.20155
In most vertebrates, the regenerative capacity to restore lost/damage tissues to original structure and functionality decreases at some time during ontogenesis. To evaluate the role of the acquired immunity in the decline of regenerative potential, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::4338e0741de4b0654cf074e3de294245
https://hdl.handle.net/11380/1111447
https://hdl.handle.net/11380/1111447
Publikováno v:
Progress in retinal and eye research. 42
Inherited maculopathies, age related macular degeneration and some forms of retinitis pigmentosa are associated with impaired function or loss of the retinal pigment epithelium (RPE). Among potential treatments, transplantation approaches are particu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c2b1e03c62bc565d3993f47ec145968
https://pubmed.ncbi.nlm.nih.gov/24933042
https://pubmed.ncbi.nlm.nih.gov/24933042
The capacity to heal wounds without scars is generally lost during the development in vertebrates. To explore the involvement of cells of the adaptive immune system in a scar-like tissue based repair, we studied the thymus in 15-month-old Xenopus aft
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9a8a452263bf10345bc04b0ff6eb146
https://hdl.handle.net/11380/1074707
https://hdl.handle.net/11380/1074707
Xenopus froglets can perfectly heal skin wounds without scarring. To explore whether this capacity is maintained as development proceeds, we examined the cellular responses during the repair of skin injury in 8- and 15-month-old Xenopus laevis. The m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b855d806191712954193be1b23386839
https://hdl.handle.net/11380/963493
https://hdl.handle.net/11380/963493
A morphofunctional analysis of the thymus from differently aged Xenopus laevis tadpoles during regeneration of the tail is reported. In stage 50 larvae, competent to regenerate, the appendage cut provoked thymic structural modifications that affected
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5533dffd1907fe7af505497703928332
https://hdl.handle.net/11380/742164
https://hdl.handle.net/11380/742164