In-target production of [11C]CH4 from a nitrogen/hydrogen gas target as a function of beam current, irradiation time, and target temperature

Autor: Semi Helin, Johan Rajander, Jussi Aromaa, Eveliina Arponen, Jatta S. Helin, Olof Solin

Publikováno v: EJNMMI Radiopharmacy and Chemistry, Vol 9, Iss 1, Pp 1-19 (2024)

Abstract Background Production of [11C]CH4 from gas targets is notorious for weak performance with respect to yield, especially when using high beam currents. Post-target conversion of [11C]CO2 to [11C]CH4 is a widely used roundabout method in 11C-ra

Externí odkaz: https://doaj.org/article/c3a3170e088d48a3ad8469f5dd8d312d

Aerobic Fitness Is Associated with Cerebral μ-Opioid Receptor Activation in Healthy Humans

Autor: TIINA SAANIJOKI, TATU KANTONEN, LAURA PEKKARINEN, KARI KALLIOKOSKI, JUSSI HIRVONEN, TUULIA MALÉN, LAURI TUOMINEN, JETRO J. TUULARI, EVELIINA ARPONEN, PIRJO NUUTILA, LAURI NUMMENMAA

Publikováno v: Medicine & Science in Sports & Exercise. 54:1076-1084

Central μ-opioid receptors (MORs) modulate affective responses to physical exercise. Individuals with higher aerobic fitness report greater exercise-induced mood improvements than those with lower fitness, but the link between cardiorespiratory fitn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d473a1842858ae6625a7859b0982e2c9
https://doi.org/10.1249/mss.0000000000002895

Aerobic fitness is associated with cerebral mu-opioid receptor availability and activation in healthy humans

Autor: Pirjo Nuutila, Kari K. Kalliokoski, Tiina Saanijoki, Laura Pekkarinen, Lauri Nummenmaa, Lauri Tuominen, Jussi Hirvonen, Tatu Kantonen, Eveliina Arponen, Jetro J. Tuulari

Central μ-opioid receptors (MORs) modulate affective responses to physical exercise. Individuals with higher aerobic fitness report greater exercise-induced mood improvements than those with lower fitness, but the link between cardiorespiratory fitn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ab3ad4946d1dbe771d08d1276fa59e9b
https://doi.org/10.1101/2020.12.13.20247627

Application of the PET Ligand 11C-ORM-13070 to Examine Receptor Occupancy by the Selective α2C-Adrenoceptor Antagonist ORM-12741: Translational Validation of Target Engagement in Rat and Human Brain

Autor: Mohammed Shahid, Juha O. Rinne, Mika Scheinin, Jere Virta, Päivi Marjamäki, Olof Solin, Eveliina Arponen, Jukka Sallinen, Katja Kuokkanen, Juha Rouru

Background Availability of the α2C -adrenoceptor (α2C-AR) positron emission tomography (PET) tracer, 11C -ORM-13070, and the selective α2C-AR antagonist ORM-12741 allows probing of the roles of this G-protein coupled receptor subtype in brain func

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a6ff85f0f659d131d0cf66fd4f68a17c
https://doi.org/10.21203/rs.3.rs-45308/v1

Brain Cholinergic Function and Response to Rivastigmine in Patients With Chronic Sequels of Traumatic Brain Injury: A PET Study

Autor: Pauliina Luoto, Jere Virta, Vesa Oikonen, Juha O. Rinne, Olli Tenovuo, Anna Östberg, Eveliina Arponen, Kjell Någren

Publikováno v: Östberg, A, Virta, J, Rinne, J O, Oikonen, V, Luoto, P, Någren, K, Arponen, E & Tenovuo, O 2018, ' Brain Cholinergic Function and Response to Rivastigmine in Patients With Chronic Sequels of Traumatic Brain Injury : A PET Study ', Journal of Head Trauma Rehabilitation, vol. 33, no. 1, pp. 25–32 . https://doi.org/10.1097/HTR.0000000000000279

OBJECTIVE:: To investigate quantitative positron emission tomography (PET) findings and to study whether the cholinergic function differs between respondents to cholinergic medication versus nonrespondents. SETTING:: Outpatient clinic and university

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c57bafaa9166c42ed800bdc2ca95f263
https://doi.org/10.1097/htr.0000000000000279