Výsledky vyhledávání - "Evelien Naessens"

Akademický článek

Diaryl ethers with carboxymethoxyphenacyl motif as potent HIV-1 reverse transcriptase inhibitors with improved solubility

Autor: Tomasz Frączek, Rafał Kamiński, Agnieszka Krakowiak, Evelien Naessens, Bruno Verhasselt, Piotr Paneth

Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 9-16 (2018)

In search of new non-nucleoside reverse transcriptase inhibitors (NNRTIs) with improved solubility, two series of novel diaryl ethers with phenacyl moiety were designed and evaluated for their HIV-1 reverse transcriptase inhibition potentials. All co

Externí odkaz: https://doaj.org/article/55073517fbfe4b95b24591fc8af6d0c0

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

HIV Triggers a cGAS-Dependent, Vpu- and Vpr-Regulated Type I Interferon Response in CD4+ T Cells

Autor: Jolien Vermeire, Ferdinand Roesch, Daniel Sauter, Réjane Rua, Dominik Hotter, Anouk Van Nuffel, Hanne Vanderstraeten, Evelien Naessens, Veronica Iannucci, Alessia Landi, Wojciech Witkowski, Ann Baeyens, Frank Kirchhoff, Bruno Verhasselt

Publikováno v: Cell Reports, Vol 17, Iss 2, Pp 413-424 (2016)

Several pattern-recognition receptors sense HIV-1 replication products and induce type I interferon (IFN-I) production under specific experimental conditions. However, it is thought that viral sensing and IFN induction are virtually absent in the mai

Externí odkaz: https://doaj.org/article/28681999f7c64ed3858dee947ca2ac9f

Zobrazit plný text záznamu

Akademický článek

Vpx-Independent Lentiviral Transduction and shRNA-Mediated Protein Knock-Down in Monocyte-Derived Dendritic Cells.

Autor: Wojciech Witkowski, Jolien Vermeire, Alessia Landi, Evelien Naessens, Hanne Vanderstraeten, Hans Nauwynck, Herman Favoreel, Bruno Verhasselt

Publikováno v: PLoS ONE, Vol 10, Iss 7, p e0133651 (2015)

The function of dendritic cells (DCs) in the immune system is based on their ability to sense and present foreign antigens. Powerful tools to research DC function and to apply in cell-based immunotherapy are either silencing or overexpression of gene

Externí odkaz: https://doaj.org/article/51652d2e10af4437b7819875c1cab063

Zobrazit plný text záznamu

Akademický článek

Lipoprotein lipase SNPs rs13702 and rs301 correlate with clinical outcome in chronic lymphocytic leukemia patients.

Autor: Ans Rombout, Basile Stamatopoulos, Laurence Lagneaux, Sofie Lust, Fritz Offner, Evelien Naessens, Hanne Vanderstraeten, Bruno Verhasselt, Jan Philippé

Publikováno v: PLoS ONE, Vol 10, Iss 3, p e0121526 (2015)

Chronic lymphocytic leukemia (CLL) is the most common leukemia in the Western world and is characterized by a heterogeneous clinical course. This variability in clinical course has spiked the search for prognostic markers able to predict patient evol

Externí odkaz: https://doaj.org/article/6226959c33774814af0730e377f1757a

Zobrazit plný text záznamu

Akademický článek

Correction: CLL Cells Respond to B-Cell Receptor Stimulation with a MicroRNA/mRNA Signature Associated with MYC Activation and Cell Cycle Progression.

Autor: Valerie Pede, Ans Rombout, Jolien Vermeire, Evelien Naessens, Pieter Mestdagh, Nore Robberecht, Hanne Vanderstraeten, Nadine Van Roy, Jo Vandesompele, Frank Speleman, Jan Philippé, Bruno Verhasselt

Publikováno v: PLoS ONE, Vol 9, Iss 1 (2014)

Externí odkaz: https://doaj.org/article/b244738001264afd90fbaae4a715e530

Zobrazit plný text záznamu

Akademický článek

CLL cells respond to B-Cell receptor stimulation with a microRNA/mRNA signature associated with MYC activation and cell cycle progression.

Publikováno v: PLoS ONE, Vol 8, Iss 4, p e60275 (2013)

Chronic lymphocytic leukemia (CLL) is a disease with variable clinical outcome. Several prognostic factors such as the immunoglobulin heavy chain variable genes (IGHV) mutation status are linked to the B-cell receptor (BCR) complex, supporting a role

Externí odkaz: https://doaj.org/article/bc19cb6061144035a4121c92fad38b19

Zobrazit plný text záznamu

Akademický článek

Quantification of reverse transcriptase activity by real-time PCR as a fast and accurate method for titration of HIV, lenti- and retroviral vectors.

Autor: Jolien Vermeire, Evelien Naessens, Hanne Vanderstraeten, Alessia Landi, Veronica Iannucci, Anouk Van Nuffel, Tom Taghon, Massimo Pizzato, Bruno Verhasselt

Publikováno v: PLoS ONE, Vol 7, Iss 12, p e50859 (2012)

Quantification of retroviruses in cell culture supernatants and other biological preparations is required in a diverse spectrum of laboratories and applications. Methods based on antigen detection, such as p24 for HIV, or on genome detection are viru

Externí odkaz: https://doaj.org/article/bf70130907834298a42cbc81ef5420e4

Zobrazit plný text záznamu

Akademický článek

Rho GTPase Cdc42 is essential for human T-cell development

Autor: Kaatje Smits, Veronica Iannucci, Veronique Stove, Peter Van Hauwe, Evelien Naessens, Pieter J. Meuwissen, Kevin K. Ariën, Mostafa Bentahir, Jean Plum, Bruno Verhasselt

Publikováno v: Haematologica, Vol 95, Iss 3 (2010)

Background Rho GTPases are involved in the regulation of many cell functions, including some related to the actin cytoskeleton. Different Rho GTPases have been shown to be important for T-cell development in mice. However, their role in human T-cell

Externí odkaz: https://doaj.org/article/7cb738978d41463eb3312e01ad0ca006

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání