Výsledky vyhledávání - "Evelien L. J. M. Smits"

Akademický článek

A systematic review on poly(I:C) and poly-ICLC in glioblastoma: adjuvants coordinating the unlocking of immunotherapy

Autor: Jorrit De Waele, Tias Verhezen, Sanne van der Heijden, Zwi N. Berneman, Marc Peeters, Filip Lardon, An Wouters, Evelien L. J. M. Smits

Publikováno v: Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-20 (2021)

Abstract Immunotherapy is currently under intensive investigation as a potential breakthrough treatment option for glioblastoma. Given the anatomical and immunological complexities surrounding glioblastoma, lymphocytes that infiltrate the brain to de

Externí odkaz: https://doaj.org/article/4e74d57df4f94a0fbb9a416bc7ae9cce

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Akademický článek

Efficient and Non-genotoxic RNA-Based Engineering of Human T Cells Using Tumor-Specific T Cell Receptors With Minimal TCR Mispairing

Autor: Diana Campillo-Davo, Fumihiro Fujiki, Johan M. J. Van den Bergh, Hans De Reu, Evelien L. J. M. Smits, Herman Goossens, Haruo Sugiyama, Eva Lion, Zwi N. Berneman, Viggo Van Tendeloo

Publikováno v: Frontiers in Immunology, Vol 9 (2018)

Genetic engineering of T cells with tumor specific T-cell receptors (TCR) is a promising strategy to redirect their specificity against cancer cells in adoptive T cell therapy protocols. Most studies are exploiting integrating retro- or lentiviral ve

Externí odkaz: https://doaj.org/article/c139e17698ca4d20b686af4b4ae43c01

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Akademický článek

Poly(I:C) enhances the susceptibility of leukemic cells to NK cell cytotoxicity and phagocytosis by DC.

Autor: Eva Lion, Sébastien Anguille, Zwi N Berneman, Evelien L J M Smits, Viggo F I Van Tendeloo

Publikováno v: PLoS ONE, Vol 6, Iss 6, p e20952 (2011)

α active specific immunotherapy aims at stimulating the host's immune system to recognize and eradicate malignant cells. The concomitant activation of dendritic cells (DC) and natural killer (NK) cells is an attractive modality for immune-based ther

Externí odkaz: https://doaj.org/article/af87beb1555644ce8817074f2c6565a6

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Loading of acute myeloid leukemia cells with poly(I:C) by electroporation

Autor: Eva, Lion, Charlotte M, de Winde, Viggo F I, Van Tendeloo, Evelien L J M, Smits

Publikováno v: Methods in molecular biology (Clifton, N.J.). 1139

In this chapter, we describe the technique of electroporation as an efficient method to load primary leukemic cells with the double-stranded RNA (dsRNA) analogue, polyriboinosinic polyribocytidylic acid (poly(I:C)), and detail on the delicate freezin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f9640eb4b398abfe18e548f350e82bfd
https://pubmed.ncbi.nlm.nih.gov/24619684

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