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Onychomycosis, the Active Invasion of a Normal Nail Unit by a Dermatophytic Versus the Colonization of an Existing Abnormal Nail Unit by Environmental Fungus

Autor: Nardo, Zaias, Sandra X, Escovar, Martin N, Zaiac, Roxana, Edwards, Melisa, Dutra, Adrian, Pona, Eve Del, Rio, Plopaylin, Jungcharoensukying

Publikováno v: Skinmed. 18(1)

Onychomycosis was described by early investigators as the presence of an abnormal nail unit and a member of the order Mycota, producing the abnormality. This interpretation has caused more than 50 years of confusion in the dermatologic literature. Un

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2de9701f9013756e7d214f79e337c15e
https://pubmed.ncbi.nlm.nih.gov/32167451

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Advances in Single-Patient Trials for Drug Treatment Optimization and Risk Management

Autor: Sidney L. Weiss, Donald P. Reitberg, Eve del Rio

Publikováno v: Drug Information Journal. 39:119-124

Experts in evidence-based medicine consider single-patient trials or “n-of-1” studies to be the highest form of evidence for making individual patient drug treatment decisions. Single-patient trial-based risk management programs for chronic care

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::14cf12473c547a263614480e3e3fb816
https://doi.org/10.1177/009286150503900202

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Efficacy and safety of clemastine-pseudoephedrine-acetaminophen versus pseudoephedrine-acetaminophen in the treatment of seasonal allergic rhinitis in a 1-day, placebo-controlled park study

Autor: Kay Weiler, Robert R. O'Connor, Eli O. Meltzer, Morris S. Gold, Eve del Rio, Thomas B. Casale, Donald Paul Reitberg, John M. Weiler

Publikováno v: Annals of Allergy, Asthma & Immunology. 90:79-86

Allergic rhinitis afflicts more than 40 million people in the United States and is a leading cause of reduced productivity at work and in school. Patients with allergic rhinitis have a wide range of symptoms that are often treated with oral combinati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::573647144e32d80576da2437fd24ab81
https://doi.org/10.1016/s1081-1206(10)63618-6

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Validation of a Single-Patient Drug Trial Methodology for Personalized Management of Gastroesophageal Reflux Disease

Autor: Barbara Wolfe, Eve del Rio, Avishai Mendelson, Sidney L. Weiss, Frederic J. Huser, Donald Paul Reitberg, Tamer A. Elbaga

Publikováno v: Journal of Managed Care Pharmacy. 8:459-468

Single-patient trials (SPTs) are randomized, often multiple-crossover trials where patients serve as their own control to determine their appropriate treatment. Historically, SPTs have been individually customized, requiring significant time and cost

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::384a3b5f6dd1a1a5d3c002222dcb63e9
https://doi.org/10.18553/jmcp.2002.8.6.459

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Single-Patient Drug Trial Methodology for Allergic Rhinitis

Autor: Eve del Rio, Donald P. Reitberg, Sidney L. Weiss, Gerbert Rebell, Nardo Zaias

Publikováno v: Annals of Pharmacotherapy. 36:1366-1374

BACKGROUND: Historically, single-patient trials (SPTs) have been specifically designed for each patient, requiring significant time and effort for execution. There has been no previous attempt to standardize an SPT for routine commercial availability

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2cbac86817e046c2250ac6697297467b
https://doi.org/10.1345/aph.1c031

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