Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Eve M. Taylor"'
Autor:
Tim Mayall, Richard J. Webby, Michael Lock, John E Ervin, Richard N. Greenberg, Glenn Ishioka, Eve M Taylor, Peter F. Wright, Marc Gurwith, John J. Treanor, Jeff Alexander, Cynthia Strout
Publikováno v:
The Lancet Infectious Diseases
Summary Background Replication-competent virus vector vaccines might have advantages compared with non-replicating vector vaccines. We tested the safety and immunogenicity of an oral adenovirus serotype 4 vector vaccine candidate (Ad4-H5-Vtn) express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd3e7af6d780aca9e3d7d86550075481
http://europepmc.org/articles/PMC3576519
http://europepmc.org/articles/PMC3576519
Publikováno v:
European Journal of Pharmacology. 534:187-193
We investigated the ability of Neotrofin, an agent that enhances endogenous nerve growth factor (NGF) levels, to prevent phenotypic, functional and structural changes that occur in the peripheral nerve of streptozotocin-diabetic rats. Eight weeks of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6c9c83799a7806129558341de5e2fd9
https://doi.org/10.1016/j.ejphar.2006.01.047
https://doi.org/10.1016/j.ejphar.2006.01.047
Publikováno v:
Psychopharmacology. 166:400-407
AIT-082 (Neotrofin), a hypoxanthine derivative, has been shown to improve memory in both animals and humans. In animals, adrenal hormones modulate the efficacy of many memory-enhancing compounds, including piracetam and tacrine (Cognex). To investiga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0cf0558b6208306324ab8cab141adbf
https://doi.org/10.1007/s00213-002-1350-5
https://doi.org/10.1007/s00213-002-1350-5
Autor:
Xiaojun Wang, Mark M. Foreman, Mahin D. Maines, Eve M. Taylor, Leslie A. Khawli, Nils Hauptmann
Publikováno v:
Brain Research. 962:1-14
There is evidence that heme oxygenase plays a role in cellular defense against reactive oxygen species and thereby has neuroprotective effects. We examined the interaction of Neotrofin, a cognitive-enhancing and neuroprotective drug, with the heme ox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2463ed218cbc3a1654501477571e39e2
https://doi.org/10.1016/s0006-8993(02)03670-3
https://doi.org/10.1016/s0006-8993(02)03670-3
Autor:
Eve M. Taylor
Publikováno v:
Clinical Pharmacokinetics. 41:81-92
The development of drugs to treat disorders of the CNS requires consideration of achievable brain concentrations. Factors that influence the brain concentrations of drugs include the rate of transport into the brain across the blood-brain barrier (BB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12087cb6dbfaa7470dca0bd33b2e9f6d
https://doi.org/10.2165/00003088-200241020-00001
https://doi.org/10.2165/00003088-200241020-00001
Publikováno v:
Journal of Neurochemistry. 57:1584-1592
Transferrin (Tf) and iron uptake by the brain were measured in rats using 59Fe-125I-Tf and 131I-albumin (to correct for the plasma content of 59Fe and 125I-Tf in the organs). The rats were aged from 15 to 63 days and were fed (a) a low-iron diet (iro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::617ef40ea007ec01dfe40a0dc32ebd4e
https://doi.org/10.1111/j.1471-4159.1991.tb06355.x
https://doi.org/10.1111/j.1471-4159.1991.tb06355.x
Autor:
Evan H. Morgan, Eve M. Taylor
Publikováno v:
Developmental Brain Research. 55:35-42
The uptake of transferrin and iron by the brain, liver and femurs was investigated in rats using 125I-59Fe-transferrin (Tf), and 131I-albumin in order to measure the plasma content of the organs. Measurements in rats ranging in age from birth to 70 d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::419d572e1e1e6024d9abb30430aaf2a5
https://doi.org/10.1016/0165-3806(90)90103-6
https://doi.org/10.1016/0165-3806(90)90103-6
Autor:
Rongzi Yan, Eve M. Taylor
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 30(5)
Neotrofin (AIT-082; leteprinim potassium) is transported out of brain by a saturable mechanism and in this study the mechanisms mediating this efflux were evaluated. Intracerebroventricular coadministration of [(14)C]Neotrofin with verapamil, a P-gly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::115692c4584924af39c94f1c4d988e76
https://pubmed.ncbi.nlm.nih.gov/11950780
https://pubmed.ncbi.nlm.nih.gov/11950780