Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Eve Lapouble"'
Autor:
Cécile Thirant, Agathe Peltier, Simon Durand, Amira Kramdi, Caroline Louis-Brennetot, Cécile Pierre-Eugène, Margot Gautier, Ana Costa, Amandine Grelier, Sakina Zaïdi, Nadège Gruel, Irène Jimenez, Eve Lapouble, Gaëlle Pierron, Déborah Sitbon, Hervé J. Brisse, Arnaud Gauthier, Paul Fréneaux, Sandrine Grossetête, Laura G. Baudrin, Virginie Raynal, Sylvain Baulande, Angela Bellini, Jaydutt Bhalshankar, Angel M. Carcaboso, Birgit Geoerger, Hermann Rohrer, Didier Surdez, Valentina Boeva, Gudrun Schleiermacher, Olivier Delattre, Isabelle Janoueix-Lerosey
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Noradrenergic and mesenchymal identities have been characterized in neuroblastoma cell lines according to their epigenetic landscapes and core regulatory circuitries. However, their relationship and relative contribution in patient tumors re
Externí odkaz:
https://doaj.org/article/04ed19984e944c97b2d0494d3dadfd31
Autor:
Birgit Geoerger, Aurélien Marabelle, Gaelle Pierron, Nadege Gruel, Arnaud Gauthier, Olivier Delattre, Gudrun Schleiermacher, Ana Costa, Cécile Thirant, Amira Kramdi, Cécile Pierre-Eugène, Caroline Louis-Brennetot, Orphée Blanchard, Didier Surdez, Eve Lapouble, Deborah Sitbon, Hervé Brisse, Paul Fréneaux, Mylène Bohec, Virginie Raynal, Sylvain Baulande, Renaud Leclere, Gabriel Champenois, Andre Nicolas, Didier Meseure, Angela Bellini, Fatima Mechta-Grigoriou, Laurie Menger, Isabelle Janoueix-Lerosey
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 8 (2022)
Background High-risk neuroblastoma is a pediatric cancer with still a dismal prognosis, despite multimodal and intensive therapies. Tumor microenvironment represents a key component of the tumor ecosystem the complexity of which has to be accurately
Externí odkaz:
https://doaj.org/article/94bfccd475c140a08e383b0eb1c1e8c1
Autor:
Peter Peneder, Adrian M. Stütz, Didier Surdez, Manuela Krumbholz, Sabine Semper, Mathieu Chicard, Nathan C. Sheffield, Gaelle Pierron, Eve Lapouble, Marcus Tötzl, Bekir Ergüner, Daniele Barreca, André F. Rendeiro, Abbas Agaimy, Heidrun Boztug, Gernot Engstler, Michael Dworzak, Marie Bernkopf, Sabine Taschner-Mandl, Inge M. Ambros, Ola Myklebost, Perrine Marec-Bérard, Susan Ann Burchill, Bernadette Brennan, Sandra J. Strauss, Jeremy Whelan, Gudrun Schleiermacher, Christiane Schaefer, Uta Dirksen, Caroline Hutter, Kjetil Boye, Peter F. Ambros, Olivier Delattre, Markus Metzler, Christoph Bock, Eleni M. Tomazou
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Liquid biopsies enable minimally invasive applications for diagnosis and treatment monitoring. Here the authors analyse fragmentation patterns of circulating tumour DNA on multiple levels and develop a bioinformatic tool, LIQUORICE, to accurately det
Externí odkaz:
https://doaj.org/article/00ea02e3e86d482ea6b429b513216011
Autor:
Shu-Hong Lin, Joshua N Sampson, Thomas G P Grünewald, Didier Surdez, Stephanie Reynaud, Olivier Mirabeau, Eric Karlins, Rebeca Alba Rubio, Sakina Zaidi, Sandrine Grossetête-Lalami, Stelly Ballet, Eve Lapouble, Valérie Laurence, Jean Michon, Gaelle Pierron, Heinrich Kovar, Udo Kontny, Anna González-Neira, Javier Alonso, Ana Patino-Garcia, Nadège Corradini, Perrine Marec Bérard, Jeremy Miller, Neal D Freedman, Nathaniel Rothman, Brian D Carter, Casey L Dagnall, Laurie Burdett, Kristine Jones, Michelle Manning, Kathleen Wyatt, Weiyin Zhou, Meredith Yeager, David G Cox, Robert N Hoover, Javed Khan, Gregory T Armstrong, Wendy M Leisenring, Smita Bhatia, Leslie L Robison, Andreas E Kulozik, Jennifer Kriebel, Thomas Meitinger, Markus Metzler, Manuela Krumbholz, Wolfgang Hartmann, Konstantin Strauch, Thomas Kirchner, Uta Dirksen, Lisa Mirabello, Margaret A Tucker, Franck Tirode, Lindsay M Morton, Stephen J Chanock, Olivier Delattre, Mitchell J Machiela
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0237792 (2020)
BackgroundEwing sarcoma (EwS) is a rare, aggressive solid tumor of childhood, adolescence and young adulthood associated with pathognomonic EWSR1-ETS fusion oncoproteins altering transcriptional regulation. Genome-wide association studies (GWAS) have
Externí odkaz:
https://doaj.org/article/f21a3cae3175421296c803674a427eeb
Autor:
Mitchell J. Machiela, Thomas G. P. Grünewald, Didier Surdez, Stephanie Reynaud, Olivier Mirabeau, Eric Karlins, Rebeca Alba Rubio, Sakina Zaidi, Sandrine Grossetete-Lalami, Stelly Ballet, Eve Lapouble, Valérie Laurence, Jean Michon, Gaelle Pierron, Heinrich Kovar, Nathalie Gaspar, Udo Kontny, Anna González-Neira, Piero Picci, Javier Alonso, Ana Patino-Garcia, Nadège Corradini, Perrine Marec Bérard, Neal D. Freedman, Nathaniel Rothman, Casey L. Dagnall, Laurie Burdett, Kristine Jones, Michelle Manning, Kathleen Wyatt, Weiyin Zhou, Meredith Yeager, David G. Cox, Robert N. Hoover, Javed Khan, Gregory T. Armstrong, Wendy M. Leisenring, Smita Bhatia, Leslie L. Robison, Andreas E. Kulozik, Jennifer Kriebel, Thomas Meitinger, Markus Metzler, Wolfgang Hartmann, Konstantin Strauch, Thomas Kirchner, Uta Dirksen, Lindsay M. Morton, Lisa Mirabello, Margaret A. Tucker, Franck Tirode, Stephen J. Chanock, Olivier Delattre
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
Ewing sarcoma (EWS) is a rare pediatric bone cancer typically involving the EWSR1-FLI1 fusion. Here the authors perform a genome-wide association study and report three new EWS risk loci that reside near GGAA repeat sequences, and identify candidate
Externí odkaz:
https://doaj.org/article/0ac8edbb89d948f498acb3404c1156e8
Autor:
Hervé J Brisse, Thomas Blanc, Gudrun Schleiermacher, Véronique Mosseri, Pascale Philippe-Chomette, Isabelle Janoueix-Lerosey, Gaelle Pierron, Eve Lapouble, Michel Peuchmaur, Paul Fréneaux, Louise Galmiche, Nathalie Algret, Matthieu Peycelon, Jean Michon, Olivier Delattre, Sabine Sarnacki
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0185190 (2017)
This study investigated relationships between neuroblastomas (NBs) imaging phenotypes, tumor genomic profile and patient outcome.This IRB-approved retrospective observational study included 133 NB patients (73 M, 60 F; median age 15 months, range 0-1
Externí odkaz:
https://doaj.org/article/1b693ed6eed64a0787baf2f73533e744
Publikováno v:
The Scientific World Journal, Vol 7, Pp 83-86 (2007)
The mutation extra-toes (Gli3Xt-J) on chromosome (Chr) 13 of the mouse is known to be involved in the development of the skeleton. The only visible manifestation is the presence of an extra digit on each hind foot. Here we report evidence from severa
Externí odkaz:
https://doaj.org/article/a9d2b407a5d64a05a134a70bec145bd9
Autor:
Anne Guimier, Sandrine Ferrand, Gaëlle Pierron, Jérôme Couturier, Isabelle Janoueix-Lerosey, Valérie Combaret, Véronique Mosseri, Estelle Thebaud, Marion Gambart, Dominique Plantaz, Aurélien Marabelle, Carole Coze, Xavier Rialland, Sylvie Fasola, Eve Lapouble, Paul Fréneaux, Michel Peuchmaur, Jean Michon, Olivier Delattre, Gudrun Schleiermacher
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101990 (2014)
Somatically acquired genomic alterations with MYCN amplification (MNA) are key features of neuroblastoma (NB), the most common extra-cranial malignant tumour of childhood. Little is known about the frequency, clinical characteristics and outcome of N
Externí odkaz:
https://doaj.org/article/07118125c58b4eaa9b23cd4a6b966103
Autor:
Olivier Delattre, Jinghui Zhang, Michael Dyer, James Downing, Ivo Gut, Perrine Marec-Bérard, Jean Michon, Valérie Laurence, Sheila Shurtleff, Richard K. Wilson, Elaine R. Mardis, Li Ding, Marta Gut, John Easton, Bhavin Vadodaria, Pankaj Gupta, Gordon Lemmon, Sakina Zaidi, Odile Oberlin, Gaelle Pierron, Xiang Chen, Gang Wu, Erin Hedlund, Thomas Rio-Frio, Stéphanie Reynaud, Michael Rusch, Sandrine Grossetête-Lalami, Eve Lapouble, Zhaojie Zhang, Armita Bahrami, Marie Cécile Le Deley, Matthew Parker, Xiaotu Ma, Didier Surdez, Franck Tirode
Supplementary Table 1 describes the clinical characteristics of patients.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1685b01b2bf8a787a868b5b88f43ad87
https://doi.org/10.1158/2159-8290.22530101
https://doi.org/10.1158/2159-8290.22530101
Autor:
Olivier Delattre, Jinghui Zhang, Michael Dyer, James Downing, Ivo Gut, Perrine Marec-Bérard, Jean Michon, Valérie Laurence, Sheila Shurtleff, Richard K. Wilson, Elaine R. Mardis, Li Ding, Marta Gut, John Easton, Bhavin Vadodaria, Pankaj Gupta, Gordon Lemmon, Sakina Zaidi, Odile Oberlin, Gaelle Pierron, Xiang Chen, Gang Wu, Erin Hedlund, Thomas Rio-Frio, Stéphanie Reynaud, Michael Rusch, Sandrine Grossetête-Lalami, Eve Lapouble, Zhaojie Zhang, Armita Bahrami, Marie Cécile Le Deley, Matthew Parker, Xiaotu Ma, Didier Surdez, Franck Tirode
Supplementary Table 4 provides the precise description of all STAG2 mutations in Ewing sarcoma.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dc0bf65ff741163625f08fba76af8f2
https://doi.org/10.1158/2159-8290.22530092
https://doi.org/10.1158/2159-8290.22530092