Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Eve E. Gardner"'
Autor:
Tristan Kempston, Megan E. Callaghan, Curt J. Essenburg, Eve E. Gardner, Roderick T. Bronson, Elizabeth A. Tovar, Ashley N. Turner, Bryn Eagleson, Anil K. Challa, Zachary Madaj, Matthew Steensma, Megan J. Bowman, Robert A. Kesterson, Carrie R. Graveel, Patrick S. Dischinger
Publikováno v:
NPJ Breast Cancer
npj Breast Cancer, Vol 4, Iss 1, Pp 1-14 (2018)
npj Breast Cancer, Vol 4, Iss 1, Pp 1-14 (2018)
The key negative regulatory gene of the RAS pathway, NF1, is mutated or deleted in numerous cancer types and is associated with increased cancer risk and drug resistance. Even though women with neurofibromatosis (germline NF1 mutations) have a substa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ba9909f4a2d4dd60a54f50da808449d
https://doi.org/10.1038/s41523-018-0080-8
https://doi.org/10.1038/s41523-018-0080-8
Autor:
Zachary Madaj, Curt J. Essenburg, Patrick S. Dischinger, Robert A. Kesterson, Matthew Steensma, Tristan Kempston, Elizabeth A. Tovar, Ashley N. Turner, Carrie R. Graveel, Eve E. Gardner, Megan J. Bowman, Bryn Eagleson, Megan E. Callaghan, Anil K. Challa, Roderick T. Bronson
Publikováno v:
Molecular Cancer Research. 16:B43-B43
Neurofibromatosis type 1 (NF1) is a common tumor predisposition syndrome caused by germline mutations in the NF1 gene that affects1 in 3,000 births. The NF1 gene encodes for neurofibromin, a GTPase that negatively regulates RAS. Women with NF1 have a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f10ac4b3c7c4cced9d4342b0e40695d7
https://doi.org/10.1158/1557-3125.advbc17-b43
https://doi.org/10.1158/1557-3125.advbc17-b43