Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Evdokia Pasheva"'
Publikováno v:
BioDiscovery, Vol 24, Iss , Pp 1-13 (2022)
HMGB1/RAGE is identified as a ligand-receptor pair that plays an important role in tumorogenesis. HMGB1 and RAGE levels are higher in most human tumors and their overexpression is associated with tumor progression. The causes of breast cancer are sti
Externí odkaz:
https://doaj.org/article/5c77b60e29bf418f98097754aa2dc396
Publikováno v:
Biotechnology & Biotechnological Equipment, Vol 33, Iss 1, Pp 645-650 (2019)
p53 is usually regarded as a tumour suppressor protein but its constant activation may result in pro-tumorigenic inflammation. The activation of p53 can be provoked by an increase in its concentration as a result of high level transcription, by trans
Externí odkaz:
https://doaj.org/article/21190274a52941bbb2dc3102d0b322a6
Autor:
Maria Schröder, Maria Petrova, Zlatina Vlahova, Georgi M. Dobrikov, Ivaylo Slavchev, Evdokia Pasheva, Iva Ugrinova
Publikováno v:
Biomedicines, Vol 10, Iss 6, p 1353 (2022)
The successful design of antitumour drugs often combines in one molecule different biologically active subunits that can affect various regulatory pathways in the cell and thus achieve higher efficacy. Two ferrocene derivatives, DK-164 and CC-78, wit
Externí odkaz:
https://doaj.org/article/dd61c85736e648348b1d16e1a100b390
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 8, p 2451 (2018)
Two paramagnetic PdIII complexes of hematoporphyrin IX ((7,12-bis(1-hydroxyethyl)-3,8,13,17-tetramethyl-21H-23H-porphyn-2,18-dipropionic acid), Hp), namely a dinuclear one [PdIII2(Hp-3H)Cl3(H2O)5]·2PdCl2, Pd1 and a mononuclear metalloporphyrin type
Externí odkaz:
https://doaj.org/article/185b2eedd42f47659ecb46a5d3099009
Publikováno v:
Proceedings of the Bulgarian Academy of Sciences. 75:1462-1468
HMGB1 protein is a DNA binding nuclear protein. Its properties to bind different non-B DNA conformations and also to bend linear DNA implicate the protein in many essential cellular processes as DNA replication, repair, transcription, remodelling, et
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::518f123401f6159c5010cbb3632ca274
https://doi.org/10.7546/crabs.2022.10.08
https://doi.org/10.7546/crabs.2022.10.08
Publikováno v:
Proceedings of the Bulgarian Academy of Sciences. 75:827-834
The Receptor of Advanced Glycated End products (RAGE) could exist in two forms, a membrane bound and a soluble one. RAGE is highly expressed during embryonic development and decreases in all tissues except the lung in adult organisms. Lung RAGE media
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e26dc7953f32705be4d744f4704a140b
https://doi.org/10.7546/crabs.2022.06.06
https://doi.org/10.7546/crabs.2022.06.06
Publikováno v:
Proceedings of the Bulgarian Academy of Sciences. 75:694-699
The receptor for advanced glycation end products (RAGE) is a cell surface multiligand receptor of the immunoglobulin superfamily. The interest of the researchers to RAGE was enhanced by the fact that it is expressed at low levels under normal physiol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::091941e19fe04271c9c5e7a2e7d6bf1d
https://doi.org/10.7546/crabs.2022.05.09
https://doi.org/10.7546/crabs.2022.05.09
Publikováno v:
International Journal of Biological Sciences, Vol 7, Iss 6, Pp 691-699 (2011)
The role of lysines 2 and 81 as target sites for acetylation in full-length HMGB1 and truncated tail-less protein, respectively, has been studied by mutation analysis for the abilities of these proteins to bind and bend DNA. The DNA bending ability o
Externí odkaz:
https://doaj.org/article/a24ba742eacb4c98bfc2afb6c6f47aed
Publikováno v:
Biotechnology & Biotechnological Equipment, Vol 33, Iss 1, Pp 645-650 (2019)
p53 is usually regarded as a tumour suppressor protein but its constant activation may result in pro-tumorigenic inflammation. The activation of p53 can be provoked by an increase in its concentration as a result of high level transcription, by trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2e55e20c25056ab5d719962ed312cdb
https://doaj.org/article/21190274a52941bbb2dc3102d0b322a6
https://doaj.org/article/21190274a52941bbb2dc3102d0b322a6
