Comparison of methods for predicting COVID-19-related death in the general population using the OpenSAFELY platform

Autor: Williamson, EJ, Tazare, J, Bhaskaran, K, McDonald, HI, Walker, AJ, Tomlinson, L, Wing, K, Bacon, S, Bates, C, Curtis, HJ, Forbes, HJ, Minassian, C, Morton, CE, Nightingale, E, Mehrkar, A, Evans, D, Nicholson, BD, Leon, DA, Inglesby, P, MacKenna, B, Davies, NG, DeVito, NJ, Drysdale, H, Cockburn, J, Hulme, WJ, Morley, J, Douglas, I, Rentsch, CT, Mathur, R, Wong, A, Schultze, A, Croker, R, Parry, J, Hester, F, Harper, S, Grieve, R, Harrison, DA, Steyerberg, EW, Eggo, RM, Diaz-Ordaz, K, Keogh, R, Evans, SJW, Smeeth, L, Goldacre, B

Publikováno v: Williamson, E J, Tazare, J, Bhaskaran, K, McDonald, H I, Walker, A J, Tomlinson, L, Wing, K, Bacon, S, Bates, C, Curtis, H J, Forbes, H J, Minassian, C, Morton, C E, Nightingale, E, Mehrkar, A, Evans, D, Nicholson, B D, Leon, D A, Inglesby, P, MacKenna, B, Davies, N G, DeVito, N J, Drysdale, H, Cockburn, J, Hulme, W J, Morley, J, Douglas, I, Rentsch, C T, Mathur, R, Wong, A, Schultze, A, Croker, R, Parry, J, Hester, F, Harper, S, Grieve, R, Harrison, D A, Steyerberg, E W, Eggo, R M, Diaz-Ordaz, K, Keogh, R, Evans, S J W & Smeeth, L & Goldacre, B 2022, ' Comparison of methods for predicting COVID-19-related death in the general population using the OpenSAFELY platform ', Diagnostic and Prognostic Research, vol. 6, no. 1, pp. 6 . https://doi.org/10.1186/s41512-022-00120-2

Background Obtaining accurate estimates of the risk of COVID-19-related death in the general population is challenging in the context of changing levels of circulating infection. Methods We propose a modelling approach to predict 28-day COVID-19-rela

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d07ce44570a9ce3555ebaa3b38522674
https://pubmed.ncbi.nlm.nih.gov/35197114

Overall and cause-specific hospitalisation and death after COVID-19 hospitalisation in England: cohort study in OpenSAFELY using linked primary care, secondary care and death registration data

Autor: Frank Hester, Christopher T Rentsch, Alex J Walker, Helen J Curtis, Peter Inglesby, Laurie A. Tomlinson, Elizabeth A. Williamson, Sam Harper, Ben Goldacre, Caroline E Morton, Amir Mehrkar, John Parry, Wong Ay, Anna Schultze, William J Hulme, Seb Bacon, Rosalind M Eggo, Charlotte Warren-Gash, Krishnan Bhaskaran, Rohini Mathur, Brian MacKenna, Liam Smeeth, V Mahalingasivam, Daniel Grint, David M. Evans, Chris Bates, Evans Sjw., Kevin Wing, George Hickman, Ian J. Douglas, Helen Mcdonald, Jonathan Cockburn

BackgroundThere is concern about medium to long-term adverse outcomes following acute COVID-19, but little relevant evidence exists. We aimed to investigate whether risks of hospital admission and death, overall and by specific cause, are raised foll

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dc5357932f986d95d6f068c9dd3d4d82
https://doi.org/10.1101/2021.07.16.21260628

OpenSAFELY: impact of national guidance on switching from warfarin to direct oral anticoagulants (DOACs) in early phase of COVID-19 pandemic in England

Autor: Tom Ward, Richard Croker, Evans Sjw., Rosalind M Eggo, Seb Bacon, John Parry, Kevin Wing, Henry Drysdale, Rohini Mathur, Simon Davy, Liam Smeeth, Anna Schultze, Frank Hester, Brian MacKenna, Amir Mehrkar, Chris Bates, Wong Ays., Laurie A. Tomlinson, Christopher T Rentsch, William J Hulme, Alex J Walker, Caroline E Morton, Jonathan Cockburn, David M. Evans, Krishnan Bhaskaran, Sam Harper, Helen Mcdonald, Ben Goldacre, Elizabeth A. Williamson, Helen J Curtis, Peter Inglesby, George Hickman, Ian J. Douglas, Harriet Forbes

Publikováno v: MedRxiv

BackgroundEarly in the COVID-19 pandemic the NHS recommended that appropriate patients anticoagulated with warfarin should be switched to direct acting oral anticoagulants (DOACs), requiring less frequent blood testing. Subsequently, a national safet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1965f6419a256be29c4d1fcd2f213d95
https://researchonline.lshtm.ac.uk/id/eprint/4659198/1/2020.12.03.20243535v1.full.pdf

Risk of COVID-19-related death among patients with chronic obstructive pulmonary disease or asthma prescribed inhaled corticosteroids:an observational cohort study using the OpenSAFELY platform

Autor: Schultze, A, Walker, AJ, MacKenna, B, Morton, CE, Bhaskaran, K, Brown, JP, Rentsch, CT, Williamson, E, Drysdale, H, Croker, R, Bacon, S, Hulme, W, Bates, C, Curtis, HJ, Mehrkar, A, Evans, D, Inglesby, P, Cockburn, J, McDonald, HI, Tomlinson, L, Mathur, R, Wing, K, Wong, AYS, Forbes, H, Parry, J, Hester, F, Harper, S, Evans, SJW, Quint, J, Smeeth, L, Douglas, IJ, Goldacre, B, OpenSAFELY Collaborative

Publikováno v: Schultze, A, Rentsch, C T, Goldacre, B, al., E & Collaborative, OAFELY 2020, ' Risk of COVID-19-related death among patients with chronic obstructive pulmonary disease or asthma prescribed inhaled corticosteroids : an observational cohort study using the OpenSAFELY platform ', Lancet Respiratory Medicine, vol. 8, no. 11, pp. 1106-1120 . https://doi.org/10.1016/s2213-2600(20)30415-x
The Lancet. Respiratory Medicine
Schultze, A, Walker, A J, MacKenna, B, Morton, C E, Bhaskaran, K, Brown, J P, Rentsch, C T, Williamson, E, Drysdale, H, Croker, R, Bacon, S, Hulme, W, Bates, C, Curtis, H J, Mehrkar, A, Evans, D, Inglesby, P, Cockburn, J, McDonald, H I, Tomlinson, L, Mathur, R, Wing, K, Wong, A Y S, Forbes, H, Parry, J, Hester, F, Harper, S, Evans, S J W, Quint, J, Smeeth, L & Douglas, I J & Goldacre, B 2020, ' Risk of COVID-19-related death among patients with chronic obstructive pulmonary disease or asthma prescribed inhaled corticosteroids : an observational cohort study using the OpenSAFELY platform ', The Lancet Respiratory Medicine, vol. 8, no. 11, pp. 1106-1120 . https://doi.org/10.1016/S2213-2600(20)30415-X

Background: Early descriptions of patients admitted to hospital during the COVID-19 pandemic showed a lower prevalence of asthma and chronic obstructive pulmonary disease (COPD) than would be expected for an acute respiratory disease like COVID-19, l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e977ffd82e12b52945645c976b2be09
https://hdl.handle.net/1983/169dbb52-48ab-4b98-8650-efd237f6e5d6

Deconstructing statistical questions: discussion

Autor: NELDER, JA, GREENFIELD, T, LENZ, HJ, CHATFIELD, C, PREECE, DA, LUNNEBORG, CE, JONES, MC, GOWER, J, STONE, RA, FESSEY, MC, EVANS, SJW, LEWIS, T, EHRENBERG, ASC, FINNEY, DJ, HERZBERG, AM, LOVIE, P, LOVIE, AD, MACKAY, RJ, OLDFORD, RW, Molenaar, IW, OBRIEN, PC, ROUANET, H, SMITH, TMF, TUKEY, J, WISE, M, ZIGHERA, J

Publikováno v: Journal of the Royal Statistical Society. Series A: Statistics in Society, 157, 338-356. Wiley

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::012eb6ab211c94d45c513bb811add3ef
https://research.rug.nl/en/publications/25f6d783-9ab9-472d-8448-3692eb733625