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Larger active site in an ancestral hydroxynitrile lyase increases catalytically promiscuous esterase activity.

Autor: Jones, Bryan J.¹ (AUTHOR), Evans III, Robert L.¹ (AUTHOR), Mylrea, Nathan J.¹ (AUTHOR), Chaudhury, Debayan¹ (AUTHOR), Luo, Christine¹ (AUTHOR), Guan, Bo¹ (AUTHOR), Pierce, Colin T.¹ (AUTHOR), Gordon, Wendy R.¹ (AUTHOR), Wilmot, Carrie M.¹ (AUTHOR), Kazlauskas, Romas J.¹ (AUTHOR) rjk@umn.edu

Publikováno v: PLoS ONE. 6/30/2020, Vol. 15 Issue 6, p1-29. 29p.

Crystal structure of the Wheat dwarf virus Rep domain.

Autor: Everett BA; Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, Minnesota, USA., Litzau LA; Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, Minnesota, USA., Tompkins K; Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, Minnesota, USA., Shi K; Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, Minnesota, USA., Nelson A; Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, Minnesota, USA., Aihara H; Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, Minnesota, USA., Evans Iii RL; Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, Minnesota, USA., Gordon WR; Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, Minnesota, USA.

Publikováno v: Acta crystallographica. Section F, Structural biology communications [Acta Crystallogr F Struct Biol Commun] 2019 Dec 01; Vol. 75 (Pt 12), pp. 744-749. Date of Electronic Publication: 2019 Nov 27.