Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Evangelos Prokakis"'
Autor:
Evangelos Prokakis, Husam Bamahmoud, Shaishavi Jansari, Lena Fritsche, Alexander Dietz, Angela Boshnakovska, Peter Rehling, Steven A. Johnsen, Julia Gallwas, Florian Wegwitz
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Background Breast cancer (BC) is the most frequent tumor entity in women worldwide with a high chance of therapeutic response in early- and non-metastatic disease stages. Among all BC subtypes, triple-negative BC (TNBC) is the most challengi
Externí odkaz:
https://doaj.org/article/f99aa535c8c1441896abb3b0036937e9
Autor:
Evangelos Prokakis, Shaishavi Jansari, Angela Boshnakovska, Maria Wiese, Kathrin Kusch, Christof Kramm, Christian Dullin, Peter Rehling, Markus Glatzel, Klaus Pantel, Harriet Wikman, Steven A. Johnsen, Julia Gallwas, Florian Wegwitz
Publikováno v:
Cell Death and Disease, Vol 14, Iss 9, Pp 1-17 (2023)
Abstract Triple-negative breast cancer (TNBC) is the most difficult breast cancer subtype to treat due to the lack of targeted therapies. Cancer stem cells (CSCs) are strongly enriched in TNBC lesions and are responsible for the rapid development of
Externí odkaz:
https://doaj.org/article/45a4565c3aba4ddb93e42ef339891e35
Autor:
Marcel Werner, Anna Dyas, Iwan Parfentev, Geske E. Schmidt, Iga K. Mieczkowska, Lukas C. Müller-Kirschbaum, Claudia Müller, Stefan Kalkhof, Oliver Reinhardt, Henning Urlaub, Frauke Alves, Julia Gallwas, Evangelos Prokakis, Florian Wegwitz
Publikováno v:
Cell Death and Disease, Vol 13, Iss 9, Pp 1-11 (2022)
Abstract Basal-like breast cancer (BLBC) is a highly aggressive breast cancer subtype frequently associated with poor prognosis. Due to the scarcity of targeted treatment options, conventional cytotoxic chemotherapies frequently remain the standard o
Externí odkaz:
https://doaj.org/article/8323616185d34c74b6e02a3d92901d16
Autor:
Iga K. Mieczkowska, Garyfallia Pantelaiou-Prokaki, Evangelos Prokakis, Geske E. Schmidt, Lukas C. Müller-Kirschbaum, Marcel Werner, Madhobi Sen, Taras Velychko, Katharina Jannasch, Christian Dullin, Joanna Napp, Klaus Pantel, Harriet Wikman, Maria Wiese, Christof M. Kramm, Frauke Alves, Florian Wegwitz
Publikováno v:
Cell Death and Disease, Vol 12, Iss 12, Pp 1-13 (2021)
Abstract Breast cancer (BC) is the most common cancer occurring in women but also rarely develops in men. Recent advances in early diagnosis and development of targeted therapies have greatly improved the survival rate of BC patients. However, the ba
Externí odkaz:
https://doaj.org/article/20c0c3f49a9e491b86d9b16315f3a86d
Autor:
Garyfallia Pantelaiou‐Prokaki, Oliver Reinhardt, Nadine S. Georges, David J. Agorku, Olaf Hardt, Evangelos Prokakis, Iga K. Mieczkowska, Wolfgang Deppert, Florian Wegwitz, Frauke Alves
Publikováno v:
International Journal of Cancer
Basal-like breast cancer (BLBC) is the most aggressive and heterogeneous breast cancer (BC) subtype. Conventional chemotherapies represent next to surgery the most frequently employed treatment options. Unfortunately, resistant tumor phenotypes often
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c40d3fd86e9a304ad41f7a3dd38fbbbd
https://hdl.handle.net/21.11116/0000-000C-AB89-921.11116/0000-000C-CB37-2
https://hdl.handle.net/21.11116/0000-000C-AB89-921.11116/0000-000C-CB37-2
Autor:
Evangelos Prokakis, Robyn Laura Kosinsky, Anna Dyas, Regina Grün, Florian Wegwitz, Upasana Bedi, Steven A. Johnsen, Zahra Basir Kazerouni, Sonja Fritzsche
Publikováno v:
Oncogene
The Ubiquitin-Specific Protease 22 (USP22) is a deubiquitinating subunit of the mammalian SAGA transcriptional co-activating complex. USP22 was identified as a member of the so-called “death-from-cancer” signature predicting therapy failure in ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b3e1dc47436fd740b8adc7a5365743d
https://doi.org/10.1038/s41388-021-01814-5
https://doi.org/10.1038/s41388-021-01814-5
Autor:
Evangelos Prokakis, Steven A. Johnsen, Ana P. Kutschat, Moyuru Yamada, Koji Tanaka, Patricia Böttcher, Xin Wang, Yuichiro Doki, Feda H. Hamdan
Publikováno v:
Cell Death and Differentiation
Esophageal squamous cell carcinoma (ESCC) is the predominant subtype of esophageal cancer with a particularly high prevalence in certain geographical regions and a poor prognosis with a 5-year survival rate of 15–25%. Despite numerous studies chara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b524def14cae7acc6aab0b1e182a78a5
https://doi.org/10.1038/s41418-021-00751-w
https://doi.org/10.1038/s41418-021-00751-w
Autor:
Steven A. Johnsen, Klaus Pantel, Anastasija Pejkovska, Markus Glatzel, Florian Wegwitz, Robyn Laura Kosinsky, Evangelos Prokakis, Harriet Wikman
Publikováno v:
Cell Death and Disease, Vol 11, Iss 10, Pp 1-14 (2020)
Cell Death & Disease
Cell Death & Disease
The HER2-positive breast cancer subtype (HER2+-BC) displays a particularly aggressive behavior. Anti-HER2 therapies have significantly improved the survival of patients with HER2+-BC. However, a large number of patients become refractory to current t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9828b424db7a0f7bb84c0bdbed965ce3
http://link.springer.com/article/10.1038/s41419-020-03081-w
http://link.springer.com/article/10.1038/s41419-020-03081-w
Autor:
Garyfallia Pantelaiou-Prokaki, Taras Velychko, Maria Wiese, Christian Dullin, Iga K Mieczkowska, Florian Wegwitz, Katharina Jannasch, Geske Schmidt, Joanna Napp, Klaus Pantel, Frauke Alves, Harriet Wikman, Marcel Werner, Madhobi Sen, Lukas C Müller-Kirschbaum, Evangelos Prokakis, Christof M. Kramm
Publikováno v:
Cell Death and Disease, Vol 12, Iss 12, Pp 1-13 (2021)
Cell Death & Disease
Cell Death & Disease
Breast cancer (BC) is the most common cancer occurring in women but also rarely develops in men. Recent advances in early diagnosis and development of targeted therapies have greatly improved the survival rate of BC patients. However, the basal-like
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1ed7e7c6595a406677cbf9053a4ff1d
https://doi.org/10.1038/s41419-021-04407-y
https://doi.org/10.1038/s41419-021-04407-y
Autor:
Garyfallia Pantelaiou-Prokaki, Iga Mieczkowska, Geske E. Schmidt, Sonja Fritzsche, Evangelos Prokakis, Julia Gallwas, Florian Wegwitz
Publikováno v:
Clinical Epigenetics
Background Basal-like breast cancer (BLBC) is one of the most aggressive malignant diseases in women with an increased metastatic behavior and poor prognosis compared to other molecular subtypes of breast cancer. Resistance to chemotherapy is the mai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95a9075fe5213340400bd0cd6337fe8b
https://pubmed.ncbi.nlm.nih.gov/35016723
https://pubmed.ncbi.nlm.nih.gov/35016723