Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Evangeline R. Jackson"'
Autor:
Alyssa Noll, Carrie Myers, Matthew C. Biery, Michael Meechan, Sophie Tahiri, Asmitha Rajendran, Michael E. Berens, Danyelle Paine, Sara Byron, Jiaming Zhang, Conrad Winter, Fiona Pakiam, Sarah E.S. Leary, Bonnie L. Cole, Evangeline R. Jackson, Matthew D. Dun, Jessica B. Foster, Myron K. Evans, Siobhan S. Pattwell, James M. Olson, Nicholas A. Vitanza
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 43, Iss , Pp 100921- (2023)
Constitutional mismatch repair deficiency (CMMRD) is a cancer predisposition syndrome associated with the development of hypermutant pediatric high-grade glioma, and confers a poor prognosis. While therapeutic histone deacetylase (HDAC) inhibition of
Externí odkaz:
https://doaj.org/article/8fcbb6db42434d30a54c41c71234e4ad
Autor:
Evangeline R. Jackson, Ryan J. Duchatel, Dilana E. Staudt, Mika L. Persson, Abdul Mannan, Sridevi Yadavilli, Sarah Parackal, Shaye Game, Wai Chin Chong, W. Samantha N. Jayasekara, Marion Le Grand, Padraic S. Kearney, Alicia M. Douglas, Izac J. Findlay, Zacary P. Germon, Holly P. McEwen, Tyrone S. Beitaki, Adjanie Patabendige, David A. Skerrett-Byrne, Brett Nixon, Nathan D. Smith, Bryan Day, Neevika Manoharan, Sumanth Nagabushan, Jordan R. Hansford, Dinisha Govender, Geoff B. McCowage, Ron Firestein, Meegan Howlett, Raelene Endersby, Nicholas G. Gottardo, Frank Alvaro, Sebastian M. Waszak, Martin R. Larsen, Yolanda Colino-Sanguino, Fatima Valdes-Mora, Andria Rakotomalala, Samuel Meignan, Eddy Pasquier, Nicolas André, Esther Hulleman, David D. Eisenstat, Nicholas A. Vitanza, Javad Nazarian, Carl Koschmann, Sabine Mueller, Jason E. Cain, Matthew D. Dun
Publikováno v:
Cancer Research. :OF1-OF17
Diffuse midline gliomas (DMG), including diffuse intrinsic pontine gliomas (DIPG), are the most lethal of childhood cancers. Palliative radiotherapy is the only established treatment, with median patient survival of 9 to 11 months. ONC201 is a DRD2 a
Autor:
Tabitha McLachlan, William C. Matthews, Evangeline R. Jackson, Dilana E. Staudt, Alicia M. Douglas, Izac J. Findlay, Mika L. Persson, Ryan J. Duchatel, Abdul Mannan, Zacary P. Germon, Matthew D. Dun
Publikováno v:
Molecular Cancer Research. 20:1711-1723
B-cell lymphoma 6 (BCL6) is a protooncogene in adult and pediatric cancers, first identified in diffuse large B-cell lymphoma (DLBCL) where it acts as a repressor of the tumor suppressor TP53, conferring survival, protection, and maintenance of lymph
Autor:
Matthew D. Dun, Jason E. Cain, Sabine Mueller, Carl Koschmann, Javad Nazarian, Nicholas A. Vitanza, David D. Eisenstat, Esther Hulleman, Nicolas André, Eddy Pasquier, Samuel Meignan, Andria Rakotomalala, Fatima Valdes-Mora, Yolanda Colino-Sanguino, Martin R. Larsen, Sebastian M. Waszak, Frank Alvaro, Nicholas G. Gottardo, Raelene Endersby, Meegan Howlett, Ron Firestein, Geoff B. McCowage, Dinisha Govender, Jordan R. Hansford, Sumanth Nagabushan, Neevika Manoharan, Bryan Day, Nathan D. Smith, Brett Nixon, David A. Skerrett-Byrne, Adjanie Patabendige, Tyrone S. Beitaki, Holly P. McEwen, Zacary P. Germon, Izac J. Findlay, Alicia M. Douglas, Padraic S. Kearney, Marion Le Grand, W. Samantha N. Jayasekara, Wai Chin Chong, Shaye Game, Sarah Parackal, Sridevi Yadavilli, Abdul Mannan, Mika L. Persson, Dilana E. Staudt, Ryan J. Duchatel, Evangeline R. Jackson
All Supplementary Figures and their captions.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d9e68dc3c6f26e99f51f1fbaa7e5b3a
https://doi.org/10.1158/0008-5472.22892044
https://doi.org/10.1158/0008-5472.22892044
Autor:
Matthew D. Dun, Jason E. Cain, Sabine Mueller, Carl Koschmann, Javad Nazarian, Nicholas A. Vitanza, David D. Eisenstat, Esther Hulleman, Nicolas André, Eddy Pasquier, Samuel Meignan, Andria Rakotomalala, Fatima Valdes-Mora, Yolanda Colino-Sanguino, Martin R. Larsen, Sebastian M. Waszak, Frank Alvaro, Nicholas G. Gottardo, Raelene Endersby, Meegan Howlett, Ron Firestein, Geoff B. McCowage, Dinisha Govender, Jordan R. Hansford, Sumanth Nagabushan, Neevika Manoharan, Bryan Day, Nathan D. Smith, Brett Nixon, David A. Skerrett-Byrne, Adjanie Patabendige, Tyrone S. Beitaki, Holly P. McEwen, Zacary P. Germon, Izac J. Findlay, Alicia M. Douglas, Padraic S. Kearney, Marion Le Grand, W. Samantha N. Jayasekara, Wai Chin Chong, Shaye Game, Sarah Parackal, Sridevi Yadavilli, Abdul Mannan, Mika L. Persson, Dilana E. Staudt, Ryan J. Duchatel, Evangeline R. Jackson
Diffuse midline gliomas (DMG), including diffuse intrinsic pontine gliomas (DIPG), are the most lethal of childhood cancers. Palliative radiotherapy is the only established treatment, with median patient survival of 9 to 11 months. ONC201 is a DRD2 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e2ec734b3b0e0b8ca6a532d4cfa2040
https://doi.org/10.1158/0008-5472.c.6651055.v1
https://doi.org/10.1158/0008-5472.c.6651055.v1
Autor:
Ryan J. Duchatel, Evangeline R. Jackson, Sarah G. Parackal, Claire Sun, Paul Daniel, Abdul Mannan, Izac J. Findlay, Dilana Staudt, Zacary P. Germon, Sandra Laternser, Dylan Kiltschewskij, Padraic S. Kearney, M. Fairuz, B. Jamaluddin, Alicia M. Douglas, Tyrone Beitaki, Mika Persson, Elizabeth E. Manning, Heather C. Murray, Nicole M. Verrills, David A. Skerrett-Byrne, Brett Nixon, Susan Hua, Valdes-Mora Fatima, Maria Tsoli, David S. Ziegler, Murray J. Cairns, Eric Raabe, Nicholas A. Vitanza, Carl Koschmann, Frank Alvaro, Christopher V. Dayas, Christopher L. Tinkle, David D. Eisenstat, Ron Firestein, Sabine Mueller, Javad Nazarian, Jason E. Cain, Matthew D. Dun
Diffuse midline glioma (DMG), including tumors diagnosed in the brainstem (diffuse intrinsic pontine glioma – DIPG), are uniformly fatal brain tumors that lack effective pharmacological treatment. Analysis of pooled CRISPR-Cas9 loss-of-function gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7761ac079918d3d90d3ed9557966419d
https://doi.org/10.1101/2023.04.17.537256
https://doi.org/10.1101/2023.04.17.537256
Autor:
Dilana E. Staudt, Heather C. Murray, David A. Skerrett-Byrne, Nathan D. Smith, M. Fairuz B. Jamaluddin, Richard G. S. Kahl, Ryan J. Duchatel, Zacary P. Germon, Tabitha McLachlan, Evangeline R. Jackson, Izac J. Findlay, Padraic S. Kearney, Abdul Mannan, Holly P. McEwen, Alicia M. Douglas, Brett Nixon, Nicole M. Verrills, Matthew D. Dun
Publikováno v:
Clinical Proteomics. 20
Autor:
Dilana E. Staudt, Heather C. Murray, David A. Skerrett-Byrne, Nathan D. Smith, M. Fairuz B. Jamaluddin, Richard G. S. Kahl, Ryan J. Duchatel, Zacary P. Germon, Tabitha McLachlan, Evangeline R. Jackson, Izac J. Findlay, Padraic S. Kearney, Abdul Mannan, Holly P. McEwen, Alicia M. Douglas, Brett Nixon, Nicole M. Verrills, Matthew D. Dun
Publikováno v:
Clinical Proteomics. 19
Global high-throughput phosphoproteomic profiling is increasingly being applied to cancer specimens to identify the oncogenic signaling cascades responsible for promoting disease initiation and disease progression; pathways that are often invisible t
Autor:
Dilana E. Staudt, Heather C. Murray, David A. Skerrett-Byrne, Nathan D. Smith, Muhammad F. Jamaluddin, Richard G.S. Kahl, Ryan J. Duchatel, Zacary Germon, Tabitha McLachlan, Evangeline R. Jackson, Izac J. Findlay, Padraic S. Kearney, Abdul Mannan, Holly P. McEwen, Alicia M. Douglas, Brett Nixon, Nicole M. Verrills, Matthew D. Dun
Global high-throughput profiling of oncogenic signaling pathways by phosphoproteomics is increasingly being applied to cancer specimens. Such quantitative unbiased phosphoproteomic profiling of cancer cells identifies oncogenic signaling cascades tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e940bd40cd1c6cf6772047149b4a68b
https://doi.org/10.1101/2022.04.22.489124
https://doi.org/10.1101/2022.04.22.489124
Autor:
Zacary P. Germon, Jonathan R. Sillar, Abdul Mannan, Ryan J. Duchatel, Dilana Staudt, Heather C. Murray, Izac J. Findlay, Evangeline R. Jackson, Holly P. McEwen, Alicia M. Douglas, Tabitha McLachlan, John E. Schjenken, David A. Skerrett-Bryne, Honggang Huang, Marcella N. Melo-Braga, Maximilian W. Plank, Frank Alvaro, Janis Chamberlain, Geoff De Iuliis, R. John Aitken, Brett Nixon, Andrew H. Wei, Anoop K. Enjeti, Richard B. Lock, Martin R. Larsen, Heather Lee, Charles E. de Bock, Nicole M. Verrills, Matthew D. Dun
FLT3-mutations are diagnosed in 25-30% of patients with acute myeloid leukemia (AML) and are associated with a poor prognosis. AML is associated with the overproduction of reactive oxygen species (ROS), which drives genomic instability through the ox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f75d81b0516ba95d61b81471b0b9c4a
https://doi.org/10.1101/2022.03.09.483687
https://doi.org/10.1101/2022.03.09.483687