Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Evangeline Deer"'
Autor:
Nathan Campbell, Evangeline Deer, Dylan Solise, Denise C. Cornelius, Ty Turner, Lorena M. Amaral, Owen Herrock, Ariel Jordan, Shivani Shukla, Tarek Ibrahim, Babbette LaMarca
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 4 (2024)
Background Preeclampsia, new‐onset hypertension during pregnancy alongside other organ dysfunction, is the leading cause of mortality for the mother and low birth weight for the baby. Low birth weight contributes to high risk of cardiovascular diso
Externí odkaz:
https://doaj.org/article/bc9482f48b3540708e4f48b304e77a8e
Autor:
Kristin E. Reeve, Evangeline Deer, Lorena M. Amaral, Denise C. Cornelius, Owen Herrock, Ashlyn C. Harmon, Nathan Campbell, Sarah Fitzgerald, Tarek Ibrahim, Gerd Wallukat, Ralf Dechend, Babbette LaMarca
Publikováno v:
Exploration of Medicine, Vol 3, Iss 1, Pp 99-111 (2022)
Aim: Preeclampsia (PE) is a hypertensive disorder of pregnancy associated with activated CD4+ T cells and autoantibodies to angiotensin II type 1 receptor (AT1-AA). We have previously shown that CD4+ T cells isolated from women with PE cause hyperte
Externí odkaz:
https://doaj.org/article/21e8269691c24173b12a14b15a263737
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Preeclampsia (PE) is a leading cause of maternal and fetal mortality worldwide. The immune system plays a critical role in normal pregnancy progression; however, inappropriate inflammatory responses have been consistently linked with PE pathophysiolo
Externí odkaz:
https://doaj.org/article/fb7bac62904b483ea8784d19ecab91aa
Autor:
Mark W. Cunningham, Aswathi Jayaram, Evangeline Deer, Lorena M. Amaral, Venkata Ramana Vaka, Tarek Ibrahim, Denise C. Cornelius, Babbette LaMarca
Publikováno v:
Hypertension in Pregnancy, Vol 39, Iss 4, Pp 399-404 (2020)
The RUPP rat model of Preeclampsia exhibits hypertension (MAP), cytolytic natural killer (cNK) cells, tumor necrosis factor alpha (TNF-α) and mitochondrial Reactive Oxygen Species (mt ROS). Objective: Does TNF-α blockade with ETAN (Etanercept) decr
Externí odkaz:
https://doaj.org/article/14cad01b54a040adabb98811b1c1884e
Publikováno v:
Antioxidants, Vol 11, Iss 2, p 210 (2022)
Despite considerable research efforts over the past few decades, the pathology of preeclampsia (PE) remains poorly understood with no new FDA-approved treatments. There is a substantial amount of work being conducted by investigators around the world
Externí odkaz:
https://doaj.org/article/d2af9bef6ec946699bd8ef20afe7c77b
Autor:
Evangeline Deer, Lorena M. Amaral, Nathan Campbell, Sarah Fitzgerald, Owen Herrock, Tarek Ibrahim, Babbette LaMarca
Publikováno v:
Cells, Vol 10, Iss 10, p 2797 (2021)
IL-2 is a cytokine released from CD4+T cells with dual actions and can either potentiate the inflammatory response or quell a chronic inflammatory response depending on its circulating concentration. IL-2 is elevated in many chronic inflammatory cond
Externí odkaz:
https://doaj.org/article/0843f3705248410a8834db4fb71f6dfc
Autor:
Evangeline Deer, Jalisa Jones, Denise C. Cornelius, Kyleigh Comley, Owen Herrock, Nathan Campbell, Sarah Fitzgerald, Tarek Ibrahim, Babbette LaMarca, Lorena M. Amaral
Publikováno v:
Cells, Vol 10, Iss 11, p 2817 (2021)
Preeclampsia (PE) is characterized by new onset hypertension in association with placental ischemia, reduced fetal weight, elevated soluble fms-like tyrosine kinase-1 (sFlt-1), and placental mitochondrial (mt) dysfunction and oxidative stress (ROS).
Externí odkaz:
https://doaj.org/article/2dd90e6416b74dd1a0a18ea6cb2c6f3e
Autor:
Sarah Fitzgerald, Evangeline Deer, James Hogg, Denise C. Cornelius, Ty Turner, Lorena M. Amaral, Ngoc Hoang, Kristin Edwards, Owen Herrock, Nathan Campbell, Tarek Ibrahim, Babbette LaMarca
Publikováno v:
Pregnancy Hypertension. 32:50-56
BACKGROUND Preeclampsia (PE), new-onset hypertension (HTN), and organ dysfunction during the second half of pregnancy, is associated with an increase in inflammatory immune cells, including T helper 17 (Th17) cells. Studies have demonstrated that mit
Autor:
Owen T. Herrock, Evangeline Deer, Lorena M. Amaral, Nathan Campbell, James Lemon, Nicole Ingram, Denise C. Cornelius, Ty W. Turner, Sarah Fitzgerald, Tarek Ibrahim, Ralf Dechend, Gerd Wallukat, Babbette LaMarca
Publikováno v:
American Journal of Physiology-Renal Physiology. 324:F179-F192
This study demonstrates that placental ischemia-stimulated B2 cells induce hypertension and circulating natural killer cell activation and angiotensin II type 1 receptor production in normal pregnant rats.
Autor:
Evangeline Deer, Owen Herrock, Nathan Campbell, Denise Cornelius, Sarah Fitzgerald, Lorena M. Amaral, Babbette LaMarca
Publikováno v:
Nature Reviews Nephrology. 19:257-270