Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Evangeline D. Motley"'
Autor:
Treniqka S. Walters, Deneshia J. McIntosh, Shalonda M. Ingram, Lakeisha Tillery, Evangeline D. Motley, Ifeanyi J. Arinze, Smita Misra
Publikováno v:
Cellular Physiology and Biochemistry, Vol 55, Iss 2, Pp 141-159 (2021)
Externí odkaz:
https://doaj.org/article/97c4496483ac43b18dade1b9cf9b57b6
Publikováno v:
The FASEB Journal. 34:1-1
Autor:
Akinari Hinoki, Timothy A. Fields, Kunie Eguchi, Heigoro Shirai, Evangeline D. Motley, Vabren L. Watts, Hiroyuki Suzuki, Satoru Eguchi, Laura N. Stemmle
Publikováno v:
Hypertension. 53:182-188
Protease-activated receptors (PARs), such as PAR1 and PAR2, have been implicated in the regulation of endothelial NO production. We hypothesized that PAR1 and PAR2 distinctly regulate the activity of endothelial NO synthase through the selective phos
Publikováno v:
Hypertension. 66
Protease-activated receptors (PARs) have been shown to regulate endothelial nitric oxide synthase (eNOS) through the activation of specific sites on the enzyme. It has been established that phosphorylation of eNOS-Ser-1177 leads to the production of
Autor:
Sudhir Dhobale, Haruhiko Ohtsu, Sadaharu Higuchi, Kunie Eguchi, Satoru Eguchi, Evangeline D. Motley, Gerald D. Frank, Hiroyuki Suzuki
Publikováno v:
Endocrinology. 147:5914-5920
Enhanced angiotensin II (AngII) action has been implicated in endothelial dysfunction that is characterized as decreased nitric oxide availability. Although endothelial cells have been reported to express AngII type 1 (AT1) receptors, the exact role
Autor:
William T. Gerthoffer, Hikaru Ueno, Satoru Eguchi, Elethia A. Woolfolk, Hidekatsu Nakashima, Evangeline D. Motley, Haruhiko Ohtsu
Publikováno v:
American Journal of Physiology-Cell Physiology. 289:C1286-C1294
ANG II promotes remodeling of vascular smooth muscle cells (VSMCs) in cardiovascular diseases. It has been shown to activate p21-activated kinase (PAK)1, a critical component of signaling pathways implicated in growth and migration. However, the deta
Publikováno v:
Antioxidants & Redox Signaling. 7:1053-1061
Although there is an abundance of evidence suggesting that insulin resistance plays a significant role in the vasculature, the precise mechanistic role involved still remains unclear. In this review, we discuss the current background of insulin resis
Autor:
Hirotoshi Utsunomiya, Nobuki Gato, Kunie Eguchi, Susumu Takekoshi, Hisao Utatsu, Mizuo Mifune, Gerald D. Frank, Trinita G. Fitzgerald, Satoru Eguchi, Evangeline D. Motley
Publikováno v:
Life Sciences. 72:659-667
Bainiku-ekisu, the fruit-juice concentrate of the Oriental plum (Prunus mume) has recently been shown to improve human blood fluidity. We have shown that angiotensin II (AngII) stimulates growth of vascular smooth muscle cells (VSMCs) through epiderm
Autor:
Motoi Ohba, Evangeline D. Motley, Gerald D. Frank, Satoru Eguchi, Shuichi Saito, Tadashi Inagami, Hirotoshi Utsunomiya, Mizuo Mifune
Publikováno v:
Journal of Biological Chemistry. 277:44695-44700
Reactive oxygen species are involved in the mitogenic signal transduction cascades initiated by several growth factors and play a critical role in mediating cardiovascular diseases. Interestingly, H(2)O(2) induces tyrosine phosphorylation and trans-a
Autor:
Peter J. Dempsey, Evangeline D. Motley, Satoru Eguchi, Shuichi Saito, Hirotoshi Utsunomiya, Tadashi Inagami, Gerald D. Frank
Publikováno v:
Biochemical and Biophysical Research Communications. 294:1023-1029
In vascular smooth muscle cells (VSMCs), angiotensin II (AngII) induces transactivation of the EGF receptor (EGFR) which involves a metalloprotease that stimulates processing of heparin-binding EGF from its precursor. However, the identity and pharma