Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Evangelia Kotsikorou"'
Publikováno v:
Endocrine Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17eee4aed49bd804181fe6778d9f1e48
https://doi.org/10.1530/endoabs.90.oc12.1
https://doi.org/10.1530/endoabs.90.oc12.1
Autor:
Thomas D. Montgomery, Joanne Rae Buchbinder, Ellen S. Gawalt, Robbie J. Iuliucci, Andrew S. Koch, Evangelia Kotsikorou, Patrick E. Lackey, Min Soo Lim, Jeffrey Joseph Rohde, Alexander J. Rupprecht, Matthew N. Srnec, Brandon Vernier, Jeffrey D. Evanseck
Publikováno v:
Journal of Chemical Education. 99:2338-2350
Scientific success in the field of chemistry depends upon the mastery of a wide range of soft skills, most notably scientific writing and speaking. However, training for scientific communication is typically limited at the undergraduate level, where
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a192a33e1d2c1a894f5d9539bfb4a66
https://doi.org/10.1021/acs.jchemed.2c00113
https://doi.org/10.1021/acs.jchemed.2c00113
Publikováno v:
Journal of the Endocrine Society
The GPR119 receptor, a class A G-protein coupled receptor located in the pancreatic β cells, induces insulin production when activated. Due to its specific activity, the pharmaceutical industry has identified GPR119 as a target for the treatment for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3efcfbc25d8058cb42f2469197ac8ebe
http://europepmc.org/articles/PMC7209689
http://europepmc.org/articles/PMC7209689
Publikováno v:
Journal of the Endocrine Society
Exposure to endocrine disrupting chemicals (EDCs) affects the function of the androgen receptor (AR) causing reproductive system problems such as reduced sperm counts, increased infertility, testicular dysgenesis syndrome, and testicular and prostate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee8c0b5468bf2707ffcfbcfa152e1e79
http://europepmc.org/articles/PMC7207291
http://europepmc.org/articles/PMC7207291
Publikováno v:
Journal of the Endocrine Society
The androgen receptor (AR) plays an important role in the development of the male phenotype and traits. Some diphenyl compounds inhibit AR activity by binding to a hydrophobic surface binding site, BF3. A similar diphenyl structure is found in 4,4’
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::224a41ff1b2ad4865b9fc383cb0eadd6
http://europepmc.org/articles/PMC7208419
http://europepmc.org/articles/PMC7208419
Autor:
Evangelia Kotsikorou, John Hamilton
Publikováno v:
Journal of computational chemistry. 39(1)
The GPR119 receptor is a class A G protein-coupled receptor expressed mainly in pancreatic beta cells. Since GPR119 receptor activation ameliorates Type 2 Diabetes through an increase in glucose-dependent insulin release, the development of new GPR11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d053d0a5b3ba11cab1e2925e8790ae48
https://pubmed.ncbi.nlm.nih.gov/29023843
https://pubmed.ncbi.nlm.nih.gov/29023843
Autor:
Evangelia Kotsikorou, Haleli Sharir, Derek M. Shore, Dow P. Hurst, Diane L. Lynch, Karla E. Madrigal, Susanne Heynen-Genel, Loribelle B. Milan, Thomas D. Y. Chung, Herbert H. Seltzman, Yushi Bai, Marc G. Caron, Larry S. Barak, Mitchell P. Croatt, Mary E. Abood, Patricia H. Reggio
Publikováno v:
Biochemistry. 52:9456-9469
GPR55 is a class A G protein-coupled receptor (GPCR) that has been implicated in inflammatory pain, neuropathic pain, metabolic disorder, bone development, and cancer. Initially deorphanized as a cannabinoid receptor, GPR55 has been shown to be activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93aa44f92150bd51a8b6796e9db78f66
https://doi.org/10.1021/bi4008885
https://doi.org/10.1021/bi4008885
Autor:
Anne Gilliam, Evangelia Kotsikorou, Diane L. Lynch, Brian F. Thomas, Zhao-Hui Song, Michael Roche, Patricia H. Reggio, Pritesh Kumar, Dow P. Hurst, Frank Navas, Herbert H. Seltzman
Publikováno v:
Journal of Medicinal Chemistry. 56:6593-6612
Despite the therapeutic promise of the subnanomolar affinity cannabinoid CB2 antagonist, 5-(4-chloro-3-methylphenyl)-1-[(4-methylphenyl)methyl]-N-[(1S,2S,4R)-1,3,3-trimethylbicyclo[2.2.1]hept-2-yl]...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1bc41fe088619c1da567a26b070167de
https://doi.org/10.1021/jm400070u
https://doi.org/10.1021/jm400070u
Publikováno v:
Chemistry and Physics of Lipids. 164:131-143
Both L-α-lysophosphatidylinositol (LPI) and 2-arachidonoyl-sn-glycero-3-phosphoinositol (2-AGPI) have been reported to activate the putative cannabinoid receptor, GPR55. Recent microsecond time-scale molecular dynamics (MD) simulations and isothiocy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d06bcc2d7690bff4363511a6892ef63
https://doi.org/10.1016/j.chemphyslip.2010.12.003
https://doi.org/10.1016/j.chemphyslip.2010.12.003
Autor:
Alexander F. Hoffman, Carl R. Lupica, Patricia H. Reggio, Daniel P. Holt, Hayden T. Ravert, Evangelia Kotsikorou, Robert F. Dannals, Dow P. Hurst, Hong Fan, Andrew G. Horti
Publikováno v:
European Journal of Medicinal Chemistry. 44:593-608
Cyano analogs of Rimonabant with high binding affinity for the cerebral cannabinoid receptor (CB1) and with optimized lipophilicity have been synthesized as potential positron emission tomography (PET) ligands. The best ligands of the series are opti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ee4b8e2240ba2666874d8f6b6651eab
https://doi.org/10.1016/j.ejmech.2008.03.040
https://doi.org/10.1016/j.ejmech.2008.03.040