Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Evangelia, Bolli"'
Autor:
Evangelia Bolli, Maximilian Scherger, Sana M. Arnouk, Ana Rita Pombo Antunes, David Straßburger, Moritz Urschbach, Judith Stickdorn, Karen De Vlaminck, Kiavash Movahedi, Hans Joachim Räder, Sophie Hernot, Pol Besenius, Jo A. Van Ginderachter, Lutz Nuhn
Publikováno v:
Advanced Science, Vol 8, Iss 10, Pp n/a-n/a (2021)
Abstract Tumor‐associated macrophages (TAMs) promote the immune suppressive microenvironment inside tumors and are, therefore, considered as a promising target for the next generation of cancer immunotherapies. To repolarize their phenotype into a
Externí odkaz:
https://doaj.org/article/cac8fa4c5d6f47508fc134a4bcd703ea
Autor:
Bart Neyns, Damya Laoui, Julia Katharina Schwarze, Helena Van Damme, Bruno Dombrecht, Máté Kiss, Heleen Roose, Eva Van Overmeire, Daliya Kancheva, Liesbet Martens, Aleksandar Murgaski, Pauline Madeleine Rachel Bardet, Gillian Blancke, Maude Jans, Evangelia Bolli, Maria Solange Martins, Yvon Elkrim, Kiavash Movahedi, Niels Vandamme, Sebahat Ocak, Isabelle Scheyltjens, Lars Vereecke, Frank Aboubakar Nana, Pascal Merchiers, Jo Agnes Van Ginderachter
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 2 (2021)
Background Modulation and depletion strategies of regulatory T cells (Tregs) constitute valid approaches in antitumor immunotherapy but suffer from severe adverse effects due to their lack of selectivity for the tumor-infiltrating (ti-)Treg populatio
Externí odkaz:
https://doaj.org/article/f3b73327b159432399d5c58c01682dd6
Autor:
Damya Laoui, Jo A. Van Ginderachter, Mohamed Lamkanfi, Andy Wullaert, Alain Beschin, Massimiliano Mazzone, Diether Lambrechts, Geert van Loo, Geert Raes, Louis Boon, Amelie Fossoul, Ayla Debraekeleer, Jan Brughmans, Maryse Schmoetten, Yvon Elkrim, Sana M. Arnouk, Pauline M.R. Bardet, Jiri Keirsse, Evangelia Bolli, Samantha Pretto, Manuel Ehling, Junbin Qian, Aleksandar Murgaski, Helena Van Damme, Els Lebegge, Pedro H.V. Saavedra, Lieselotte Vande Walle, Máté Kiss
Supplementary Figures 1-11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ac555aa6d9d63833368748b3be0a555
https://doi.org/10.1158/2326-6066.22543494
https://doi.org/10.1158/2326-6066.22543494
Autor:
Damya Laoui, Jo A. Van Ginderachter, Mohamed Lamkanfi, Andy Wullaert, Alain Beschin, Massimiliano Mazzone, Diether Lambrechts, Geert van Loo, Geert Raes, Louis Boon, Amelie Fossoul, Ayla Debraekeleer, Jan Brughmans, Maryse Schmoetten, Yvon Elkrim, Sana M. Arnouk, Pauline M.R. Bardet, Jiri Keirsse, Evangelia Bolli, Samantha Pretto, Manuel Ehling, Junbin Qian, Aleksandar Murgaski, Helena Van Damme, Els Lebegge, Pedro H.V. Saavedra, Lieselotte Vande Walle, Máté Kiss
IL1β is a central mediator of inflammation. Secretion of IL1β typically requires proteolytic maturation by the inflammasome and formation of membrane pores by gasdermin D (GSDMD). Emerging evidence suggests an important role for IL1β in promoting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17834bb72b19f02c483a544d32dc5d61
https://doi.org/10.1158/2326-6066.c.6550290
https://doi.org/10.1158/2326-6066.c.6550290
Autor:
Jina Ko, Martin Wilkovitsch, Juhyun Oh, Rainer H. Kohler, Evangelia Bolli, Mikael J. Pittet, Claudio Vinegoni, David B. Sykes, Hannes Mikula, Ralph Weissleder, Jonathan C. T. Carlson
Publikováno v:
Nat Biotechnol
Cells in complex organisms undergo frequent functional changes, but few methods allow comprehensive longitudinal profiling of living cells. Here we introduce scission-accelerated fluorophore exchange (SAFE), a method for multiplexed temporospatial im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::032b742d047621608767c7cfd5cbd273
https://doi.org/10.1038/s41587-022-01339-6
https://doi.org/10.1038/s41587-022-01339-6
Autor:
Damya Laoui, Jiri Keirsse, Yannick Morias, Eva Van Overmeire, Xenia Geeraerts, Yvon Elkrim, Mate Kiss, Evangelia Bolli, Qods Lahmar, Dorine Sichien, Jens Serneels, Charlotte L. Scott, Louis Boon, Patrick De Baetselier, Massimiliano Mazzone, Martin Guilliams, Jo A. Van Ginderachter
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-17 (2016)
Dendritic cells are antigen-presenting cells consisting of distinct subsets originating from different lineages. Here, the authors identify the subsets of dendritic cells populating the tumour tissue in both mice and humans and find they have opposin
Externí odkaz:
https://doaj.org/article/a203b2adbb4344c7be80bcf4c68f425a
Autor:
Maximilian Scherger, Evangelia Bolli, Ana Rita Pombo Antunes, Sana Arnouk, Judith Stickdorn, Alexandra Van Driessche, Hansjörg Schild, Stephan Grabbe, Bruno G. De Geest, Jo A. Van Ginderachter, Lutz Nuhn
Publikováno v:
Cells, Vol 9, Iss 10, p 2222 (2020)
To target nanomedicines to specific cells, especially of the immune system, nanobodies can be considered as an attractive tool, as they lack the Fc part as compared to traditional antibodies and, thus, prevent unfavorable Fc-receptor mediated mistarg
Externí odkaz:
https://doaj.org/article/da8008b0c0bf450e8efd7d18830ad2da
Autor:
Jeremy Gungabeesoon, Nicolas A. Gort-Freitas, Máté Kiss, Evangelia Bolli, Marius Messemaker, Marie Siwicki, Mehdi Hicham, Ruben Bill, Peter Koch, Chiara Cianciaruso, Florent Duval, Christina Pfirschke, Michael Mazzola, Solange Peters, Krisztian Homicsko, Christopher Garris, Ralph Weissleder, Allon M. Klein, Mikael J. Pittet
Publikováno v:
Cell. 186:1448-1464.e20
Neutrophils accumulate in solid tumors, and their abundance correlates with poor prognosis. Neutrophils are not homogeneous, however, and could play different roles in cancer therapy. Here, we investigate the role of neutrophils in immunotherapy, lea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4243a20d97fd467032576bb1217ffbc
https://doi.org/10.1016/j.cell.2023.02.032
https://doi.org/10.1016/j.cell.2023.02.032
Autor:
Nicolas A. Gort-Freitas, Christina Pfirschke, Anna Kohl, Doron Merkler, Marie Siwicki, Yoshiko Iwamoto, Chiara Cianciaruso, Rapolas Zilionis, Marius Messemaker, Sara I. Pai, John E. Mindur, Montserrat Fraga, Pierre-Yves Dietrich, Angela E. Zou, Alexander Coukos, Christine Sempoux, Yi-Jang Lin, Nilesh Talele, Cecile Piot, Thibaud Koessler, Alexandre Wicky, Rakesh K. Jain, Yunkang Lin, Mikael J. Pittet, Rainer H. Kohler, Ruben Bill, Christopher Garris, Camilla Engblom, Jeremy Gungabeesoon, Allon M. Klein, Claudio deVito, Olivier Michielin, Ralph Weissleder, Evangelia Bolli, Genevieve M. Gerhard, Mari Mino-Kenudson
Publikováno v:
Sci Immunol
Science Immunology, Vol. 6, No 61 (2021) P. eabi7083
Science Immunology, Vol. 6, No 61 (2021) P. eabi7083
Immunotherapy is revolutionizing cancer treatment but is often restricted by toxicities. What distinguishes adverse events from concomitant antitumor reactions is poorly understood. Here, using anti-CD40-treatment in mice as a model of Th1-promoting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b9db22b1b089ff465f17caa910096aa
https://doi.org/10.1126/sciimmunol.abi7083
https://doi.org/10.1126/sciimmunol.abi7083
Autor:
Ana Rita Pombo Antunes, Tony Lahoutte, Ahmet Krasniqi, Emile J. Clappaert, Aleksandar Murgaski, Kiavash Movahedi, Marnik Vuylsteke, Amanda Gonçalves, Geert Stangé, Nick Devoogdt, Jo A. Van Ginderachter, Geert Raes, Matthias D'Huyvetter, Evangelia Bolli, Danielle Berus, Sana M. Arnouk
Publikováno v:
Journal of Controlled Release. 314:1-11
Radioimmunotherapy (RIT) aims to deliver a high radiation dose to cancer cells, while minimizing the exposure of normal cells. Typically, monoclonal antibodies are used to target the radionuclides to cancer cell surface antigens. However, antibodies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1457d1668ae746271e47c55fe72d4720
https://doi.org/10.1016/j.jconrel.2019.10.024
https://doi.org/10.1016/j.jconrel.2019.10.024