Zobrazeno 1 - 10
of 176
pro vyhledávání: '"Evandro Fei, Fang"'
Autor:
Anne-Brita Knapskog, Trine Holt Edwin, Per Magne Ueland, Arve Ulvik, Evandro Fei Fang, Rannveig Sakshaug Eldholm, Nathalie Bodd Halaas, Lasse M. Giil, Ingvild Saltvedt, Leiv Otto Watne, Mari Aksnes
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-14 (2024)
Abstract Background Sex differences in neuroinflammation could contribute to women’s increased risk of Alzheimer’s disease (AD), providing rationale for exploring sex-specific AD biomarkers. In AD, dysregulation of the kynurenine pathway (KP) con
Externí odkaz:
https://doaj.org/article/5756027d5d874a8f9b16adf7278e48c7
Autor:
Yuyao Tian, Sofie Lautrup, Patrick Wai Nok Law, Ngoc-Duy Dinh, Evandro Fei Fang, Wai-Yee Chan
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract Background Metabolic dysfunction is one of the main symptoms of Werner syndrome (WS); however, the underlying mechanisms remain unclear. Here, we report that loss of WRN accelerates adipogenesis at an early stage both in vitro (stem cells) a
Externí odkaz:
https://doaj.org/article/590e422dd0744c8aa85d87446ce950c2
Autor:
Yuyao Tian, Wuming Wang, Sofie Lautrup, Hui Zhao, Xiang Li, Patrick Wai Nok Law, Ngoc-Duy Dinh, Evandro Fei Fang, Hoi Hung Cheung, Wai-Yee Chan
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Short stature is a hallmark of Werner Syndrome, but the underlying mechanisms are not well studied. Here they report that WRN regulates bone development and growth by opening SHOX-G-quadruplexes via its helicase activity both in vitro and in vivo.
Externí odkaz:
https://doaj.org/article/5cf95fd306b348f2bda0e4413752072d
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Externí odkaz:
https://doaj.org/article/bb5ac9570cc44762bd0273bea2f08857
Publikováno v:
STAR Protocols, Vol 4, Iss 2, Pp 102250- (2023)
Summary: Here, we present an olfactory-dependent chemotaxis assay for evaluating changes in memory-like behavior in both wild-type and Alzheimer’s-disease-like C. elegans models. We describe steps for synchronizing and preparing C. elegans populati
Externí odkaz:
https://doaj.org/article/737020570c124c2da7a3bd3537c65f9c
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Externí odkaz:
https://doaj.org/article/edd8a92728eb452080622e4ba6ce86a2
Autor:
Francisco José Naranjo-Galindo, Ruixue Ai, Evandro Fei Fang, Hilde Loge Nilsen, Tanima SenGupta
Publikováno v:
Frontiers in Aging, Vol 3 (2022)
Since its introduction as a genetic model organism, Caenorhabditis elegans has yielded insights into the causes of aging. In addition, it has provided a molecular understanding of mechanisms of neurodegeneration, one of the devastating effects of agi
Externí odkaz:
https://doaj.org/article/8cd9ee72575047619756f7ac32b7d610
Autor:
Nengzhi Pang, Qianrong Hu, Yujia Zhou, Ying Xiao, Wenli Li, Yijie Ding, Yunan Chen, Mingtong Ye, Lei Pei, Qiuyan Li, Yingying Gu, Yan Sun, Evandro Fei Fang, Mianrong Chen, Zhenfeng Zhang, Lili Yang
Publikováno v:
Nutrients, Vol 15, Iss 6, p 1447 (2023)
Targeting Nicotinamide adenine dinucleotide (NAD) metabolism has emerged as a promising anti-cancer strategy; we aimed to explore the health benefits of boosting NAD levels with nicotinamide riboside (NR) on hepatocellular carcinoma (HCC). We establi
Externí odkaz:
https://doaj.org/article/15da507ddddb4129934b85edfb155325
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/e97f58e6f7f34069a7fc81e8e13bade7
Autor:
Shaoping Hu, Yuan Gao, Zhangming Niu, Yinghui Jiang, Lao Li, Xianglu Xiao, Minhao Wang, Evandro Fei Fang, Wade Menpes-Smith, Jun Xia, Hui Ye, Guang Yang
Publikováno v:
IEEE Access, Vol 8, Pp 118869-118883 (2020)
An outbreak of a novel coronavirus disease (i.e., COVID-19) has been recorded in Wuhan, China since late December 2019, which subsequently became pandemic around the world. Although COVID-19 is an acutely treated disease, it can also be fatal with a
Externí odkaz:
https://doaj.org/article/33ff80bdfafb4b9ebd7010bede8fd636