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Publikováno v:
The FASEB Journal. 33
Autor:
Karyn O'neil, Robert V. Kolakowski, Steven G. Nadler, Kulkarni Swapnil, Addis Russell C, Joshua Gorsky, Xin Yao, Evana Mortezavi, Rebecca Meyer
Publikováno v:
Cancer Research. 80:1825-1825
KRAS has been the quintessential undruggable oncogene for many years. Although there have been recently described small molecule inhibitors of KRAS, these molecules only target a specific mutant form, KRAS G12C. The KRAS G12C mutation represents just