Zobrazeno 1 - 10
of 303
pro vyhledávání: '"Evan Y, Snyder"'
Publikováno v:
STAR Protocols, Vol 5, Iss 2, Pp 103025- (2024)
Summary: The Rice-Vannucci model in rodent pups is subject to substantial loss of animals, result inconsistency, and high lab-to-lab variability in extent and composition of induced injury. This protocol allows for highly predictable and reproducible
Externí odkaz:
https://doaj.org/article/ac4d03ed669946dfb5c8b52c9deee080
Autor:
Wen-Ning Zhao, Brian T. D. Tobe, Namrata D. Udeshi, Lucius L. Xuan, Cameron D. Pernia, Daniel P. Zolg, Amanda J. Roberts, Deepak Mani, Sarah R. Blumenthal, Iren Kurtser, Debasis Patnaik, Irina Gaisina, Joshua Bishop, Steven D. Sheridan, Jasmin Lalonde, Steven A. Carr, Evan Y. Snyder, Stephen J. Haggarty
Publikováno v:
Translational Psychiatry, Vol 10, Iss 1, Pp 1-18 (2020)
Abstract The effective treatment of bipolar disorder (BD) represents a significant unmet medical need. Although lithium remains a mainstay of treatment for BD, limited knowledge regarding how it modulates affective behavior has proven an obstacle to
Externí odkaz:
https://doaj.org/article/3adcd41d1c9642cb98771f72e34b370f
Publikováno v:
Cell Transplantation, Vol 30 (2021)
When using human induced pluripotent stem cells (hiPSCs) to achieve hair follicle (HF) replacement, we found it best to emulate the earliest fundamental developmental processes of gastrulation, ectodermal lineage commitment, and dermogenesis. Viewing
Externí odkaz:
https://doaj.org/article/c8d737f06fd643ea93d5231e5a1014f7
Nna1 gene deficiency triggers Purkinje neuron death by tubulin hyperglutamylation and ER dysfunction
Autor:
Jianxue Li, Evan Y. Snyder, Fenny H.F. Tang, Renata Pasqualini, Wadih Arap, Richard L. Sidman
Publikováno v:
JCI Insight, Vol 5, Iss 19 (2020)
Posttranslational glutamylation/deglutamylation balance in tubulins influences dendritic maturation and neuronal survival of cerebellar Purkinje neurons (PNs). PNs and some additional neuronal types degenerate in several spontaneous, independently oc
Externí odkaz:
https://doaj.org/article/ae2da415ddf04f47b7b57947e2315661
Autor:
Hanna Sabelström, Rebecca Petri, Ksenya Shchors, Rahul Jandial, Christin Schmidt, Rohit Sacheva, Selma Masic, Edith Yuan, Trenten Fenster, Michael Martinez, Supna Saxena, Theodore P. Nicolaides, Shirin Ilkhanizadeh, Mitchel S. Berger, Evan Y. Snyder, William A. Weiss, Johan Jakobsson, Anders I. Persson
Publikováno v:
Cell Reports, Vol 28, Iss 8, Pp 2064-2079.e11 (2019)
Summary: Identifying cellular programs that drive cancers to be stem-like and treatment resistant is critical to improving outcomes in patients. Here, we demonstrate that constitutive extracellular signal-regulated kinase 1/2 (ERK1/2) activation sust
Externí odkaz:
https://doaj.org/article/057d899aad464389833a8cc12ce5d423
Autor:
Ilyas Singec, Andrew M. Crain, Junjie Hou, Brian T.D. Tobe, Maria Talantova, Alicia A. Winquist, Kutbuddin S. Doctor, Jennifer Choy, Xiayu Huang, Esther La Monaca, David M. Horn, Dieter A. Wolf, Stuart A. Lipton, Gustavo J. Gutierrez, Laurence M. Brill, Evan Y. Snyder
Publikováno v:
Stem Cell Reports, Vol 7, Iss 3, Pp 527-542 (2016)
Controlled differentiation of human embryonic stem cells (hESCs) can be utilized for precise analysis of cell type identities during early development. We established a highly efficient neural induction strategy and an improved analytical platform, a
Externí odkaz:
https://doaj.org/article/03e02bec095e4ecea0312b9f57adc932
Autor:
Sandra L. Leibel, Rachael N. McVicar, Rabi Murad, Elizabeth M. Kwong, Alex E. Clark, Asuka Alvarado, Bethany A. Grimmig, Ruslan Nuryyev, Randee E. Young, Jamie Casey Lee, Weiqi Peng, Yanfang Peipei Zhu, Eric Griffis, Cameron J. Nowell, Kang Liu, Brian James, Suzie Alarcon, Atul Malhotra, Linden J. Gearing, Paul J. Hertzog, Cheska Marie Galapate, Koen M.O. Galenkamp, Cosimo Commisso, Davey M. Smith, Xin Sun, Aaron F. Carlin, Ben A. Croker, Evan Y. Snyder
Publikováno v:
bioRxiv
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) causes an acute respiratory distress syndrome (ARDS) that resembles surfactant deficient RDS. Using a novel multi-cell type, human induced pluripotent stem cell (hiPSC)-derived lung organoi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::176b7be3e6c03821db5f1393dae1180d
https://doi.org/10.1101/2023.01.26.525578
https://doi.org/10.1101/2023.01.26.525578
Publikováno v:
Cell Transplantation, Vol 27 (2018)
The interaction of SDF-1α (also known as CXCL12) with the CXCR4 receptor plays a critical role in the retention of hematopoietic stem cells (HSCs) in bone marrow. The viral macrophage inflammatory protein-II (vMIP-II), a human herpesvirus-8 (HHV-8)-
Externí odkaz:
https://doaj.org/article/7e7874ae681e4dde9e963abf8b172167
Autor:
Lisette M. Acevedo, Jeffrey N. Lindquist, Breda M. Walsh, Peik Sia, Flavio Cimadamore, Connie Chen, Martin Denzel, Cameron D. Pernia, Barbara Ranscht, Alexey Terskikh, Evan Y. Snyder, David A. Cheresh
Publikováno v:
Stem Cell Reports, Vol 4, Iss 6, Pp 1075-1088 (2015)
To gain insight into the cellular and molecular cues that promote neurovascular co-patterning at the earliest stages of human embryogenesis, we developed a human embryonic stem cell model to mimic the developing epiblast. Contact of ectoderm-derived
Externí odkaz:
https://doaj.org/article/06246247775f42d7b312dc2b3d07c835
Autor:
Yoshihiko Nakamura, Takafumi Nakano, Ji Hyun Park, Masayoshi Tanaka, Wenlu Li, Elga Esposito, Bum Ju Ahn, Violeta Durán-Laforet, Rakhi Desai, Ikbal Sencan, Sava Sakadžić, Eng H. Lo, Evan Y. Snyder, Marcin Tabaka, Kazuhide Hayakawa
SummaryThe neural crest (NC) is a transient structure in vertebrate embryogenesis comprising highly migratory multipotent stem cells that give rise to a diverse array of cell types in organs throughout the body, including initiating neurovascular pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79c841a79d4eeff51d8d1a2847e43adb
https://doi.org/10.1101/2022.12.30.522316
https://doi.org/10.1101/2022.12.30.522316