Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Evan S. Bardot"'
Autor:
Chee-Huat Linus Eng, Benjamin D. Simons, J. Nichols, John C. Marioni, Ricard Argelaguet, James Briscoe, Tim Lohoff, Evan S. Bardot, Carolina Guibentif, Nico Pierson, Shankar Srinivas, Bertie Gottgens, Wolf Reik, Jonathan A. Griffiths, Richard C. V. Tyser, Anna-Katerina Hadjantonakis, Shila Ghazanfar, Noushin Koulena, Long Cai, A. Missarova
Transcriptional and epigenetic profiling of single-cells has advanced our knowledge of the molecular bases of gastrulation and early organogenesis. However, current approaches rely on dissociating cells from tissues, thereby losing the crucial spatia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfc611d53780940717e1583850650218
https://doi.org/10.1101/2020.11.20.391896
https://doi.org/10.1101/2020.11.20.391896
Autor:
Andrew J. Sharp, Evan S. Bardot, Nadeera Wickramasinghe, Michael Rendl, Bharati Jadhav, Amélie Rezza, Nicole Dubois
During development multiple progenitor populations contribute to the formation of the four-chambered heart and its diverse lineages. However, the underlying mechanisms that result in the specification of these progenitor populations are not yet fully
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::294a8c8f31099b18b91c76a620a7ab0c
https://doi.org/10.1101/2020.02.20.958348
https://doi.org/10.1101/2020.02.20.958348
Autor:
Nicole Dubois, Evan S. Bardot
Publikováno v:
Cell
Collateral arteries are an uncommon vessel subtype that can provide alternate blood flow to preserve tissue following vascular occlusion. Some patients with heart disease develop collateral coronary arteries, and this correlates with increased surviv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86e9a84571fee7f2823d5ec38fd5d49a
https://europepmc.org/articles/PMC8240015/
https://europepmc.org/articles/PMC8240015/
Publikováno v:
Developmental Dynamics. 245:1130-1144
Scientists have studied organs and their development for centuries and, along that path, described models and mechanisms explaining the developmental principles of organogenesis. In particular, with respect to the heart, new fundamental discoveries a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0fb3c299de9363a043b8f72e20fa893c
https://doi.org/10.1002/dvdy.24441
https://doi.org/10.1002/dvdy.24441
Publikováno v:
Mech Dev
During mouse embryonic development a mass of pluripotent epiblast tissue is transformed during gastrulation to generate the three definitive germ layers: endoderm, mesoderm, and ectoderm. During gastrulation, a spatiotemporally controlled sequence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7af5db6faa5794089a2a20c08d02eea3
https://doi.org/10.1016/j.mod.2020.103617
https://doi.org/10.1016/j.mod.2020.103617
Autor:
Wendy Keung, Kevin D. Costa, Peter Backeris, Evan S. Bardot, Camie W.Y. Chan, Bryce V. Johnson, Patrick K. W. Chan, Ronald A. Li, Andy O.-T. Wong, Timothy J. Cashman
Tissue engineers and stem cell biologists have made exciting progress toward creating simplified models of human heart muscles or aligned monolayers to help bridge a longstanding gap between experimental animals and clinical trials. However, no exist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1c272d7e49721ef3c3154026097d751
https://europepmc.org/articles/PMC6561506/
https://europepmc.org/articles/PMC6561506/
Publikováno v:
Journal of Visualized Experiments.
The use of ever-advancing imaging techniques has contributed broadly to our increased understanding of embryonic development. Pre-implantation development and organogenesis are two areas of research that have benefitted greatly from these advances, d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c55b080b38c8aaa70f0d0472cba96a3
https://doi.org/10.3791/56446
https://doi.org/10.3791/56446
Autor:
Stanley Artap, Nicole Dubois, Bharati Jadhav, Songyan Han, Valerie Gouon-Evans, Ingo Burtscher, Heiko Lickert, Evan S. Bardot, Andrew J. Sharp, Francis J. Santoriello, Damelys Calderon, Kakit Cheung, Jonathan I. Epstein, Rajan Jain
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Nat. Commun. 8:14428 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Nat. Commun. 8:14428 (2017)
The recent identification of progenitor populations that contribute to the developing heart in a distinct spatial and temporal manner has fundamentally improved our understanding of cardiac development. However, the mechanisms that direct atrial vers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8075918698d279e542450cdcf8a4ee81
http://europepmc.org/articles/PMC5316866
http://europepmc.org/articles/PMC5316866
Autor:
Wendy Keung, Ronald A. Li, Evan S. Bardot, Timothy J. Cashman, Bryce V. Johnson, Camie W. Chan, Patrick K. W. Chan, Andy O.-T. Wong, Kevin D. Costa, Peter Backeris
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 99:106595
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d114e50720ac1d581097da68ff87a7f
https://doi.org/10.1016/j.vascn.2019.05.178
https://doi.org/10.1016/j.vascn.2019.05.178
Autor:
Evan S. Bardot, Jose M. Silva, Carolina N. Perdigoto, Víctor Valdés, Silvia K. Nicolis, Jisheng Zhang, Stephen Hearn, Elena Ezhkova
Publikováno v:
The EMBO Journal. 32:1990-2000
While the Polycomb complex is known to regulate cell identity in ES cells, its role in controlling tissue-specific stem cells is not well understood. Here we show that removal of Ezh1 and Ezh2, key Polycomb subunits, from mouse skin results in a mark
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8e73d4026c52ac8576a07565aa1023d
https://doi.org/10.1038/emboj.2013.110
https://doi.org/10.1038/emboj.2013.110