Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Evan S, Snitkin"'
Autor:
Qiwen Dong, Huaiying Lin, Marie-Maude Allen, Julian R. Garneau, Jonathan K. Sia, Rita C. Smith, Fidel Haro, Tracy McMillen, Rosemary L. Pope, Carolyn Metcalfe, Victoria Burgo, Che Woodson, Nicholas Dylla, Claire Kohout, Anitha Sundararajan, Evan S. Snitkin, Vincent B. Young, Louis-Charles Fortier, Mini Kamboj, Eric G. Pamer
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112861- (2023)
Summary: Clostridioides difficile produces toxins that damage the colonic epithelium, causing colitis. Variation in disease severity is poorly understood and has been attributed to host factors and virulence differences between C. difficile strains.
Externí odkaz:
https://doaj.org/article/e4b8e0b177bf436b902ce1c02e6ae79c
Autor:
Jay Vornhagen, Emily K. Roberts, Lavinia Unverdorben, Sophia Mason, Alieysa Patel, Ryan Crawford, Caitlyn L. Holmes, Yuang Sun, Alexandra Teodorescu, Evan S. Snitkin, Lili Zhao, Patricia J. Simner, Pranita D. Tamma, Krishna Rao, Keith S. Kaye, Michael A. Bachman
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Patient variables, such as comorbidities, partially explain which patients will progress to Klebsiella infection, with colonization of the gut acting as a reservoir. Little is known, however, regarding Klebsiella genes that may increase risk of disea
Externí odkaz:
https://doaj.org/article/9fca71bb880145e79855025ffb4001fa
Autor:
Arwen E. Frick-Cheng, Anna Sintsova, Sara N. Smith, Ali Pirani, Evan S. Snitkin, Harry L. T. Mobley
Publikováno v:
mBio, Vol 13, Iss 3 (2022)
ABSTRACT More than half of women will experience a urinary tract infection (UTI), with uropathogenic Escherichia coli (UPEC) causing ~80% of uncomplicated cases. Iron acquisition systems are essential for uropathogenesis, and UPEC strains encode high
Externí odkaz:
https://doaj.org/article/44c625d9a85448c6b49a3823b1ef5635
Autor:
Ryan D. Crawford, Evan S. Snitkin
Publikováno v:
BMC Bioinformatics, Vol 22, Iss 1, Pp 1-10 (2021)
Abstract Background The quantity of genomic data is expanding at an increasing rate. Tools for phylogenetic analysis which scale to the quantity of available data are required. To address this need, we present cognac, a user-friendly software package
Externí odkaz:
https://doaj.org/article/d015fd73dff04d3dabe8e331920223f2
Autor:
Sarah E. Sansom, Emily Benedict, Stephanie N. Thiede, Bala Hota, Alla Aroutcheva, Darjai Payne, Chad Zawitz, Evan S. Snitkin, Stefan J. Green, Robert A. Weinstein, Kyle J. Popovich
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 1 (2021)
ABSTRACT Methicillin-resistant Staphylococcus aureus (MRSA) is a leading cause of health care-associated (HA) and community-associated (CA) infections. USA300 strains are historically CA-MRSA, while USA100 strains are HA-MRSA. Here, we update an anti
Externí odkaz:
https://doaj.org/article/8069c774db7446e893b58ebe3148e77d
Autor:
Mark T. Anderson, Aric N. Brown, Ali Pirani, Sara N. Smith, Amanda L. Photenhauer, Yuang Sun, Evan S. Snitkin, Michael A. Bachman, Harry L. T. Mobley
Publikováno v:
mBio, Vol 12, Iss 4 (2021)
ABSTRACT Bloodstream infections (BSI) are a major public health burden due to high mortality rates and the cost of treatment. The impact of BSI is further compounded by a rise in antibiotic resistance among Gram-negative species associated with these
Externí odkaz:
https://doaj.org/article/ddd4a91eb3004209a0e9be83e9243df5
Autor:
Zena Lapp, Jennifer H. Han, Jenna Wiens, Ellie J. C. Goldstein, Ebbing Lautenbach, Evan S. Snitkin
Publikováno v:
mSystems, Vol 6, Iss 2 (2021)
ABSTRACT Carbapenem-resistant Klebsiella pneumoniae (CRKP) is a critical-priority antibiotic resistance threat that has emerged over the past several decades, spread across the globe, and accumulated resistance to last-line antibiotic agents. While C
Externí odkaz:
https://doaj.org/article/e8a14616b13a4fc7a207d161292ad7e2
Autor:
Hannah D. Steinberg, Evan S. Snitkin
Publikováno v:
mSphere, Vol 5, Iss 6 (2020)
ABSTRACT Illness caused by the pathogen Clostridioides difficile is widespread and can range in severity from mild diarrhea to sepsis and death. Strains of C. difficile isolated from human infections exhibit great genetic diversity, leading to the hy
Externí odkaz:
https://doaj.org/article/466239aadb084103b01db1dea3ded1f6
Autor:
Anna Sintsova, Arwen E Frick-Cheng, Sara Smith, Ali Pirani, Sargurunathan Subashchandrabose, Evan S Snitkin, Harry Mobley
Publikováno v:
eLife, Vol 8 (2019)
Uropathogenic Escherichia coli (UPEC) is the major causative agent of uncomplicated urinary tract infections (UTIs). A common virulence genotype of UPEC strains responsible for UTIs is yet to be defined, due to the large variation of virulence factor
Externí odkaz:
https://doaj.org/article/43dc7bcd0bed4eff969fec9a9b401e29
Autor:
Theresa Mau, Samantha S. Eckley, Ingrid L. Bergin, Katie Saund, Jason S. Villano, Kimberly C. Vendrov, Evan S. Snitkin, Vincent B. Young, Raymond Yung
Publikováno v:
mSphere, Vol 4, Iss 2 (2019)
ABSTRACT Between October 2016 and June 2017, a C57BL/6J mouse colony that was undergoing a pre- and perinatal methyl donor supplementation diet intervention to study the impact of parental nutrition on offspring susceptibility to disease was found to
Externí odkaz:
https://doaj.org/article/19c8e35455f045948cb484f50caff1d2