Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Evan R. Himes"'
Autor:
Jeffrey S. Boyles, Dorota Sadowski, Scott Potter, Aleksandra Vukojicic, James Parker, William Y. Chang, Yanfei L. Ma, Mark G. Chambers, James Nelson, Barbra Barmettler, Eric M. Smith, Kara Kersjes, Evan R. Himes, Chaohua Lin, Jonathan Lucchesi, Jaladhi Brahmbhatt, Ramtin Sina, Jennifer A. Martin, Evan Maestri, Christopher M. Wiethoff, Gregory L. Dyas, Matthew D. Linnik, Songqing Na, Derrick R. Witcher, Alison Budelsky, Kira Rubtsova
Publikováno v:
JCI Insight, Vol 8, Iss 13 (2023)
B cells contribute to multiple aspects of autoimmune disorders, and B cell–targeting therapies, including B cell depletion, have been proven to be efficacious in treatment of multiple autoimmune diseases. However, the development of novel therapies
Externí odkaz:
https://doaj.org/article/71aa2cc4be704328879505e403536058
Autor:
Kylie A. Corry, Hongkang Zhou, Tatiana Brustovetsky, Evan R. Himes, Nicoletta Bivi, M. Ryne Horn, Yukiko Kitase, Joseph M. Wallace, Teresita Bellido, Nickolay Brustovetsky, Jiliang Li
Publikováno v:
Bone Reports, Vol 11, Iss , Pp - (2019)
Signal transducer and activator of transcription 3 (Stat3) is a member of the Stat family of proteins involved in signaling in many different cell types, including osteocytes. Osteocytes are considered major mechanosensing cells in bone due to their
Externí odkaz:
https://doaj.org/article/6bddb5fdd5124e1c8669a20c252aee8c
Autor:
Safa F. Mohamad, Linlin Xu, Joydeep Ghosh, Paul J. Childress, Irushi Abeysekera, Evan R. Himes, Hao Wu, Marta B. Alvarez, Korbin M. Davis, Alexandra Aguilar-Perez, Jung Min Hong, Angela Bruzzaniti, Melissa A. Kacena, Edward F. Srour
Publikováno v:
Blood Advances, Vol 1, Iss 26, Pp 2520-2528 (2017)
Abstract: Networking between hematopoietic stem cells (HSCs) and cells of the hematopoietic niche is critical for stem cell function and maintenance of the stem cell pool. We characterized calvariae-resident osteomacs (OMs) and their interaction with
Externí odkaz:
https://doaj.org/article/89476a8aba184a4a89e2166a32d286fb
Autor:
Evan R. Himes, Kevin A. Maupin, Joydeep Ghosh, Louis M. Pelus, Christie M. Orschell, Paul Childress, Alexa Fisher, Marta B. Alvarez, Jung Min Hong, Irushi Abeysekera, Edward F. Srour, Pratibha Singh, Artur P. Plett, Safa F. Mohamad, Carol H. Sampson, Melissa A. Kacena, Angela Bruzzaniti, Hui Lin Chua
Publikováno v:
Bone
Osteoblast number and activity decreases with aging, contributing to the age-associated decline of bone mass, but the mechanisms underlying changes in osteoblast activity are not well understood. Here, we show that the age-associated bone loss critic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed75ee58449e23bdae08dea993e4a6de
https://doi.org/10.1016/j.bone.2019.07.010
https://doi.org/10.1016/j.bone.2019.07.010
Autor:
Rebecca K. Davidson, Jiliang Li, Andrew V. Nguyen, Hiroki Yokota, Tomas E. Meijome, Shinya Takigawa, Evan R. Himes, M. Ryne Horn, Melissa A. Kacena, Andy Chen, Joseph M. Wallace
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 7, p e0236891 (2020)
PLoS ONE, Vol 15, Iss 7, p e0236891 (2020)
Signal Transducer and Activator of Transcription 3 (STAT3) has recently been shown to be involved in bone development and has been implicated in bone diseases, such as Job's Syndrome. Bone growth and changes have been known for many years to differ b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78db88ae4b2f97501dc9afe92a4f4b84
http://europepmc.org/articles/PMC7392311
http://europepmc.org/articles/PMC7392311
Autor:
Vruti Patel, Evan R. Himes, Jung Min Hong, Pierre P. Eleniste, Sumana Posritong, Patrick W. McIntyre, Melissa A. Kacena, Jennifer L. Wu, Angela Bruzzaniti
Publikováno v:
Molecular and Cellular Endocrinology. 474:35-47
Bone remodeling is controlled by the actions of bone-degrading osteoclasts and bone-forming osteoblasts (OBs). Aging and loss of estrogen after menopause affects bone mass and quality. Estrogen therapy, including selective estrogen receptor modulator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daa84882468a5468c3ea134daa075fdb
https://doi.org/10.1016/j.mce.2018.02.005
https://doi.org/10.1016/j.mce.2018.02.005
Autor:
Joseph M. Wallace, Yukiko Kitase, Hongkang Zhou, Jiliang Li, Tatiana Brustovetsky, Evan R. Himes, Nickolay Brustovetsky, M. Ryne Horn, Nicoletta Bivi, Kylie A. Corry, Teresita Bellido
Publikováno v:
Bone Reports
Bone Reports, Vol 11, Iss, Pp-(2019)
Bone Reports, Vol 11, Iss, Pp-(2019)
Signal transducer and activator of transcription 3 (Stat3) is a member of the Stat family of proteins involved in signaling in many different cell types, including osteocytes. Osteocytes are considered major mechanosensing cells in bone due to their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6de75ee437855a81336e6d315b630a7a
http://europepmc.org/articles/PMC6700265
http://europepmc.org/articles/PMC6700265
Autor:
Joydeep Ghosh, Hao Wu, Linlin Xu, Evan R. Himes, Edward F. Srour, Marta B. Alvarez, Safa F. Mohamad, Jung Min Hong, Korbin M. Davis, Paul Childress, Angela Bruzzaniti, Irushi Abeysekera, Alexandra Aguilar-Perez, Melissa A. Kacena
Publikováno v:
Blood advances. 1(26)
Networking between hematopoietic stem cells (HSCs) and cells of the hematopoietic niche is critical for stem cell function and maintenance of the stem cell pool. We characterized calvariae-resident osteomacs (OMs) and their interaction with megakaryo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8125a651935ad613d1def7f9d575b26e
https://pubmed.ncbi.nlm.nih.gov/29296903
https://pubmed.ncbi.nlm.nih.gov/29296903
Autor:
Melissa A. Kacena, Jenna T. Baughman, Heather Largura, Angela Bruzzaniti, Pierre P. Eleniste, Vruti Patel, Sumana Posritong, Odette Zero, Evan R. Himes, Matthew J. Hamilton, Ying Hua Cheng
Osteoblast differentiation and migration are necessary for bone formation during bone remodeling. Mice lacking the proline-rich tyrosine kinase Pyk2 (Pyk2-KO) have increased bone mass, in part due to increased osteoblast proliferation. Megakaryocytes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af6cf276d1ce364653e41bdcf65e5815
https://europepmc.org/articles/PMC4821770/
https://europepmc.org/articles/PMC4821770/
Autor:
Yong-Xin Sun, Guoli Dai, Lei Li, Pei Zhang, Kylie A. Corry, Evan R. Himes, Yang Yang, Jiliang Li, Cristina Layla Mihuti, Cecilia Nelson
Publikováno v:
Bone. 74
Nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcription factor expressed in many cell types, including osteoblasts, osteocytes, and osteoclasts. Nrf2 has been considered a master regulator of cytoprotective genes against oxidative and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fd7a1baaaa41e14f21f21e5455209e9
https://pubmed.ncbi.nlm.nih.gov/25576674
https://pubmed.ncbi.nlm.nih.gov/25576674