Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Evan P Booy"'
Autor:
Edis Dzananovic, Astha, Grzegorz Chojnowski, Soumya Deo, Evan P Booy, Pauline Padilla-Meier, Kevin McEleney, Janusz M Bujnicki, Trushar R Patel, Sean A McKenna
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186849 (2017)
Highly structured RNA derived from viral genomes is a key cellular indicator of viral infection. In response, cells produce the interferon inducible RNA-dependent protein kinase (PKR) that, when bound to viral dsRNA, phosphorylates eukaryotic initiat
Externí odkaz:
https://doaj.org/article/84fd847862b04e2c823b1f4366e567eb
Autor:
Emmanuel O Ariyo, Evan P Booy, Trushar R Patel, Edis Dzananovic, Ewan K McRae, Markus Meier, Kevin McEleney, Jorg Stetefeld, Sean A McKenna
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144510 (2015)
Nucleic acids rich in guanine are able to fold into unique structures known as G-quadruplexes. G-quadruplexes consist of four tracts of guanylates arranged in parallel or antiparallel strands that are aligned in stacked G-quartet planes. The structur
Externí odkaz:
https://doaj.org/article/09bafcf3bcda4fa283619b50b11332a5
Autor:
Soumya Deo, Trushar R Patel, Edis Dzananovic, Evan P Booy, Khalid Zeid, Kevin McEleney, Stephen E Harding, Sean A McKenna
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92545 (2014)
West Nile virus (WNV) has a positive sense RNA genome with conserved structural elements in the 5' and 3' -untranslated regions required for polyprotein production. Antiviral immunity to WNV is partially mediated through the production of a cluster o
Externí odkaz:
https://doaj.org/article/c340459956e04d00b0b3f472c7a1ecaf
Publikováno v:
Journal of Nucleic Acids, Vol 2017 (2017)
Guanine quadruplexes (G4s) are four-stranded secondary structures of nucleic acids which are stabilized by noncanonical hydrogen bonding systems between the nitrogenous bases as well as extensive base stacking, or pi-pi, interactions. Formation of th
Externí odkaz:
https://doaj.org/article/662a9fbabf7b4efc8bedde280078f228
Publikováno v:
RNA. :rna.079649.123
The SRP9/SRP14 heterodimer is a central component of signal recognition particle (SRP) RNA (7SL) processing and Alu retrotransposition. In this study, we sought to establish the role of nuclear SRP9/SRP14 in the transcriptional regulation of 7SL and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad417cf6db723e743987756b5e485587
https://doi.org/10.1261/rna.079649.123
https://doi.org/10.1261/rna.079649.123
Publikováno v:
Biochemistry and Cell Biology. 98:70-82
Human 2′–5′ oligoadenylate synthetases (OAS) are a family of interferon-inducible proteins that, upon activation by double-stranded RNA, polymerize ATP into 2′–5′ linked oligoadenylates. In this study, we probed the RNA cofactor specifici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14db81eb4a3d88bc3bbd2fc823d8cb01
https://doi.org/10.1139/bcb-2019-0060
https://doi.org/10.1139/bcb-2019-0060
Publikováno v:
The Journal of Biological Chemistry
BC200 is a noncoding RNA elevated in a broad spectrum of tumor cells that is critical for cell viability, invasion, and migration. Overexpression studies have implicated BC200 and the rodent analog BC1 as negative regulators of translation in both ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9804f920a4de4611fea5ce19f2963b30
http://europepmc.org/articles/PMC7949042
http://europepmc.org/articles/PMC7949042
Autor:
Evan P. Booy, Taegi Choi, Daniel Gussakovsky, Ewan K.S. McRae, Sean A. McKenna, Peyman Ezzati
Publikováno v:
Nucleic Acids Research
BC200 is a long non-coding RNA primarily expressed in brain but aberrantly expressed in various cancers. To gain a further understanding of the function of BC200, we performed proteomic analyses of the BC200 ribonucleoprotein (RNP) by transfection of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8577d99356cefa62c1e9028e4c94865e
https://doi.org/10.1093/nar/gky860
https://doi.org/10.1093/nar/gky860
Autor:
Ewan K.S. McRae, Natalie Krahn, Kevin McEleney, Aniel Moya-Torres, George L. Orriss, Jörg Stetefeld, Trushar R. Patel, Matthew McDougall, Markus Meier, Evan P. Booy, Sean A. McKenna
Publikováno v:
Nucleic Acids Research
The identification of four-stranded G-quadruplexes (G4s) has highlighted the fact that DNA has additional spatial organisations at its disposal other than double-stranded helices. Recently, it became clear that the formation of G4s is not limited to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99f26ed58e603c0bdb28a8ff835f3cdf
https://doi.org/10.1093/nar/gky307
https://doi.org/10.1093/nar/gky307
Autor:
Jörg Stetefeld, Trushar R. Patel, Sean A. McKenna, Markus Meier, Natalie Krahn, Evan P. Booy, Darren L. Gemmill, Amit Koul, Nikhat Lubna
Publikováno v:
Biophysical Journal
Oligoadenylate synthetases (OASs) are a family of interferon-inducible enzymes that require double-stranded RNA (dsRNA) as a cofactor. Upon binding dsRNA, OAS undergoes a conformational change and is activated to polymerize ATP into 2′-5′-oligoad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09c2a5ea21a961c037632edef3b14358
https://pubmed.ncbi.nlm.nih.gov/32413313
https://pubmed.ncbi.nlm.nih.gov/32413313