Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Evan Onusko"'
Autor:
Evan Onusko, Michael R McDermott, Nathan Robbins, Guansheng Liu, Evangelia G Kranias, Jack Rubinstein, Sheryl E Koch
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0230386 (2020)
Probenecid has been used for decades in the treatment of gout but recently has also been found to improve outcomes in patients with heart failure via stimulation of the transient receptor potential vanilloid 2 (TRPV2) channel in cardiomyocytes. This
Externí odkaz:
https://doaj.org/article/594e8b50cc3f4a2cace73ed4c6e98bca
Autor:
Mindi Naticchioni, Rajiv Karani, Margaret A Smith, Evan Onusko, Nathan Robbins, Min Jiang, Tatiana Radzyukevich, Logan Fulford, Xu Gao, Ryan Apel, Judith Heiny, Jack Rubinstein, Sheryl E Koch
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0136901 (2015)
The myocardial response to exercise is an adaptive mechanism that permits the heart to maintain cardiac output via improved cardiac function and development of hypertrophy. There are many overlapping mechanisms via which this occurs with calcium hand
Externí odkaz:
https://doaj.org/article/4751311f17d44395a63516911f0a520e
Autor:
Jack Rubinstein, Guan-Sheng Liu, Evangelia G. Kranias, Nathan Robbins, Sheryl E. Koch, Evan Onusko, Michael R. McDermott
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0230386 (2020)
PLoS ONE
PLoS ONE
Probenecid has been used for decades in the treatment of gout but recently has also been found to improve outcomes in patients with heart failure via stimulation of the transient receptor potential vanilloid 2 (TRPV2) channel in cardiomyocytes. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eeb94fc3ae01244c4a4b330fdb1cdc40
https://doaj.org/article/594e8b50cc3f4a2cace73ed4c6e98bca
https://doaj.org/article/594e8b50cc3f4a2cace73ed4c6e98bca
Autor:
Evan Onusko, Samuel Slone, Steve Kraynik, Sheryl E. Koch, Umesh Singh, Jack Rubinstein, Michael Tranter
Publikováno v:
The FASEB Journal. 28
Transient receptor potential vanilloid 2 (TRPV2) is a ligand-gated ion channel that is expressed in cadiomyocytes and increases contractility following stimulation with probenecid, an agonist for T...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eded8be85a2708c73346e5a43f9ab5fa
https://doi.org/10.1096/fasebj.28.1_supplement.545.4
https://doi.org/10.1096/fasebj.28.1_supplement.545.4