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Short nucleotide polymorphic insertions in the MCL-1 promoter affect gene expression

Autor: Keith Bonham, Igor Moshynskyy, Tania Qureshi, Anurag Saxena, Evan Neuls, Mark Bosch, Michael Voralia, Oksana Moshynska

Publikováno v: Cancer Letters. 251:114-131

We have recently reported novel short nucleotide (six and eighteen) polymorphic insertions, in the MCL-1 promoter and their association with higher mRNA and protein levels. The aim of the present study was to test the hypothesis that these insertions

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea180a4a85772676bb1246abef96ba56
https://doi.org/10.1016/j.canlet.2006.11.007

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G125A Single Nucleotide Polymorphism (SNP) in 5′-UTR of the Tumor Suppressor Gene Bax Affects Its Transcriptional Regulation

Autor: Evan Neuls, Anurag Saxena, Oksana Moshynska, Keith Bonham

Publikováno v: Blood. 108:2250-2250

Lower expression of Bax protein in various human malignancies is associated with poor response to treatment and shorter disease-free survival. We (Cancer Lett2002; 187:199–205) and others (J Clin Oncol; 23:1514–21) have shown the association of a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::66280320e98e9dc2ee240a0bfdafbfb0
https://doi.org/10.1182/blood.v108.11.2250.2250

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