Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Evan N. Graf"'
Autor:
Evan N. Graf, Elizabeth M. Doncheck, David A. Baker, Benjamin F. Cravatt, Cecilia J. Hillard, John R. Mantsch, Daisuke Ogasawara, Yan Li, Jayme R. McReynolds, Qing-song Liu, Oliver Vranjkovic
Publikováno v:
Biological Psychiatry. 84:85-94
Background Clinical reports suggest that rather than directly driving cocaine use, stress may create a biological context within which other triggers for drug use become more potent. We hypothesize that stress-induced increases in corticosterone “s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::979b06c494780a64ad842a9cd98c3909
https://doi.org/10.1016/j.biopsych.2017.09.024
https://doi.org/10.1016/j.biopsych.2017.09.024
Publikováno v:
Hormones and Behavior. 82:1-10
The neurodevelopmental fetal alcohol spectrum disorder (FASD) is characterized by cognitive and behavioral deficits in the offspring. Conferring the deficits to the next generation would increase overall FASD disease burden and prevention of this tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27d55ddcef145402505fdf069104a1ff
https://doi.org/10.1016/j.yhbeh.2016.04.002
https://doi.org/10.1016/j.yhbeh.2016.04.002
Publikováno v:
Psychoneuroendocrinology. 45:187-191
Insulin-like growth factor 2 (Igf2) regulates development, memory and adult neurogenesis in the hippocampus. Calorie restriction (CR) is known to modulate non-neuronal Igf2 expression intergenerationally, but its effect has not been evaluated on brai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ab1d1b3e6aecdafa16db03d575d1f06
https://doi.org/10.1016/j.psyneuen.2014.04.002
https://doi.org/10.1016/j.psyneuen.2014.04.002
Autor:
Daniel S. Wheeler, Robert A. Wheeler, Mykel A. Robble, Evan N. Graf, Jayme R. McReynolds, Paul J. Gasser, John R. Mantsch, David A. Baker, Oliver Vranjkovic, Jonathan E. Hill, Amanda L. Ebben
Publikováno v:
Journal of Neuroscience. 33:11800-11810
Stressful life events are important contributors to relapse in recovering cocaine addicts, but the mechanisms by which they influence motivational systems are poorly understood. Studies suggest that stress may "set the stage" for relapse by increasin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5521f4cf88a43970db25cfba4491058d
https://doi.org/10.1523/jneurosci.1969-13.2013
https://doi.org/10.1523/jneurosci.1969-13.2013
Autor:
Michael A. Hoks, David A. Baker, Colin Bohr, Jean Baumgardner, John R. Mantsch, Evan N. Graf, Jose Sierra, Oliver Vranjkovic
Publikováno v:
Neuropsychopharmacology. 36:1444-1454
Understanding the neurobiological processes that contribute to the establishment and expression of stress-induced regulation of cocaine use in addicted individuals is important for the development of new and better treatment approaches. It has been p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c5a4c56ee37e82a7adb9079225b748f
https://doi.org/10.1038/npp.2011.28
https://doi.org/10.1038/npp.2011.28
Publikováno v:
Frontiers in Genetics
Frontiers in Genetics, Vol 5 (2014)
Frontiers in Genetics, Vol 5 (2014)
Fetal alcohol spectrum disorder (FASD) presents a collection of symptoms representing physiological and behavioral phenotypes caused by maternal alcohol consumption. Symptom severity is modified by genetic differences in fetal susceptibility and resi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fde864fa6ea01e374797a2062d7610f
https://doi.org/10.3389/fgene.2014.00261
https://doi.org/10.3389/fgene.2014.00261
Consequences of prenatal exposure to ethanol (E) include morphological, physiological, and cognitive deficits and are collectively classified as fetal alcohol spectrum disorders. Adult prenatal E exposed offspring show insulin resistance, and given t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee61e4d4e959e77c62113074681536da
https://europepmc.org/articles/PMC4073969/
https://europepmc.org/articles/PMC4073969/
Publikováno v:
Translational Psychiatry
In this study, we sought to learn whether adverse events such as chronic restraint stress (CRS), or ‘nurture’ in the form of environmental enrichment (EE), could modify depression-like behavior and blood biomarker transcript levels in a genetic r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77f4fd2bcb0925fb4ef49deaae024b2d
https://doi.org/10.1038/tp.2016.28
https://doi.org/10.1038/tp.2016.28
Autor:
Jordan M. Blacktop, Nathan Ferda, David A. Baker, John R. Mantsch, Geng Lee, Chad Seubert, Evan N. Graf
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 31(31)
Stressful events are determinants of relapse in recovering cocaine addicts. Excessive cocaine use may increase susceptibility to stressor-induced relapse through alterations in brain corticotropin-releasing factor (CRF) regulation of neurocircuitry i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::676d18cee6e70dac8f356ec173dc1899
https://pubmed.ncbi.nlm.nih.gov/21813699
https://pubmed.ncbi.nlm.nih.gov/21813699
Autor:
Evan N. Graf, Christopher R. Mueller, Colin Bohr, Samantha Wisniewski, Shi-Jiang Li, Oliver Vranjkovic, David A. Baker, John R. Mantsch, Zheng Yang, Yazmin Figueroa-Guzman
Publikováno v:
Drug and alcohol dependence. 116(1-3)
Cocaine addiction is characterized by a persistently heightened susceptibility to drug relapse. For this reason, the identification of medications that prevent drug relapse is a critical goal of drug abuse research. Drug re-exposure, the onset of str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06d3aa9bf1364ab590bd8e414fc02009
https://pubmed.ncbi.nlm.nih.gov/21196089
https://pubmed.ncbi.nlm.nih.gov/21196089